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Hua Huang
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Neutrophil extracellular traps accumulate in peripheral blood vessels and compromise organ function in tumor-bearing animals
J Cedervall, Y Zhang, H Huang, L Zhang, J Femel, A Dimberg, AK Olsson
Cancer research 75 (13), 2653-2662, 2015
2272015
VEGF suppresses T‐lymphocyte infiltration in the tumor microenvironment through inhibition of NF‐κB‐induced endothelial activation
H Huang, E Langenkamp, M Georganaki, A Loskog, PF Fuchs, ...
The FASEB Journal 29 (1), 227-238, 2015
1792015
Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF‐A and TGFβ2 in vascular abnormalization
LC Dieterich, S Mellberg, E Langenkamp, L Zhang, A Zieba, H Salomäki, ...
The Journal of pathology 228 (3), 378-390, 2012
1692012
Key molecular alterations in endothelial cells in human glioblastoma uncovered through single-cell RNA sequencing
Y Xie, L He, R Lugano, Y Zhang, H Cao, Q He, M Chao, B Liu, Q Cao, ...
JCI insight 6 (15), 2021
852021
Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma
L van Hooren, A Vaccaro, M Ramachandran, K Vazaios, S Libard, ...
Nature Communications 12 (1), 4127, 2021
702021
Elevated expression of the C-type lectin CD93 in the glioblastoma vasculature regulates cytoskeletal rearrangements that enhance vessel function and reduce host survival
E Langenkamp, L Zhang, R Lugano, H Huang, TEA Elhassan, ...
Cancer research 75 (21), 4504-4516, 2015
702015
Sunitinib enhances the antitumor responses of agonistic CD40-antibody by reducing MDSCs and synergistically improving endothelial activation and T-cell recruitment
L van Hooren, M Georganaki, H Huang, SM Mangsbo, A Dimberg
Oncotarget 7 (31), 50277, 2016
412016
αB-crystallin/HspB5 regulates endothelial–leukocyte interactions by enhancing NF-κB-induced up-regulation of adhesion molecules ICAM-1, VCAM-1 and E-selectin
LC Dieterich, H Huang, S Massena, N Golenhofen, M Phillipson, ...
Angiogenesis 16, 975-983, 2013
332013
Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy
M Georganaki, M Ramachandran, S Tuit, NG Núñez, A Karampatzakis, ...
Oncoimmunology 9 (1), 1730538, 2020
282020
Fgfbp1 promotes blood-brain barrier development by regulating collagen IV deposition and maintaining Wnt/β-catenin signaling
A Cottarelli, M Corada, GV Beznoussenko, AA Mironov, MA Globisch, ...
Development 147 (16), dev185140, 2020
252020
Inflammation and neutrophil extracellular traps in cerebral cavernous malformation
ACY Yau, MA Globisch, FC Onyeogaziri, LL Conze, R Smith, ...
Cellular and Molecular Life Sciences 79 (4), 206, 2022
162022
ELTD1 deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma
H Huang, M Georganaki, LL Conze, B Laviña, L van Hooren, K Vemuri, ...
Neuro-oncology 24 (3), 398-411, 2022
102022
Wnt signaling regulates MFSD2A-dependent drug delivery through endothelial transcytosis in glioma
Y Xie, L He, Y Zhang, H Huang, F Yang, M Chao, H Cao, J Wang, Y Li, ...
Neuro-oncology 25 (6), 1073-1084, 2023
62023
αB-Crystallin regulates expansion of CD11b+ Gr-1+ immature myeloid cells during tumor progression
LC Dieterich, P Schiller, H Huang, EF Wawrousek, A Loskog, A Wanders, ...
The FASEB Journal 27 (1), 151, 2013
62013
SproutAngio: An open-source bioimage informatics tool for quantitative analysis of sprouting angiogenesis and lumen space
M Beter, A Abdollahzadeh, HH Pulkkinen, H Huang, F Orsenigo, ...
Scientific Reports 13 (1), 7279, 2023
32023
Agonistic CD40 antibody therapy induces tertiary lymphoid structures but impairs the response to immune checkpoint blockade in glioma
L van Hooren, A Vaccaro, M Ramachandran, K Vazaios, S Libard, ...
bioRxiv, 2021.01. 05.425377, 2021
22021
Multispectral imaging identifies CD93 as a tumor endothelial marker associated with vascular proliferation and poor patient survival in glioblastoma
K Vemuri, A Klemm, H Huang, L Wik, A Mezheyeuski, A Östman, A Smits, ...
2022
Abstract A128: Tumor endothelial cells say IDO to CD40-stimulating immunotherapy
A Dimberg, A Karampatzakis, S Tuit, M Ramachandran, G Fotaki, ...
Cancer Immunology Research 7 (2_Supplement), A128-A128, 2019
2019
Abstract A159: Agonistic CD40 antibody therapy induces formation of tertiary lymphoid structures in glioma and inhibits the response to immune-checkpoint blockade
L Hooren, A Vaccaro, M Georganaki, M Ramachandran, H Huang, J Lau, ...
Cancer Immunology Research 7 (2_Supplement), A159-A159, 2019
2019
Tumor endothelial up-regulation of IDO1 is an immunosuppressive feedback mechanism that limits the response to CD40-stimulating immunotherapy
M Georganaki, A Karampatzakis, S Tuit, G Fotaki, L van Hooren, H Huang, ...
2018
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