Spiroindolones, a potent compound class for the treatment of malaria M Rottmann, C McNamara, BKS Yeung, MCS Lee, B Zou, B Russell, ... science 329 (5996), 1175-1180, 2010 | 1199 | 2010 |
Bi-directional protein transport between the ER and Golgi MCS Lee, EA Miller, J Goldberg, L Orci, R Schekman Annu. Rev. Cell Dev. Biol. 20, 87-123, 2004 | 1096 | 2004 |
Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles EA Miller, TH Beilharz, PN Malkus, MCS Lee, S Hamamoto, L Orci, ... Cell 114 (4), 497-509, 2003 | 635 | 2003 |
Sar1p N-terminal helix initiates membrane curvature and completes the fission of a COPII vesicle MCS Lee, L Orci, S Hamamoto, E Futai, M Ravazzola, R Schekman Cell 122 (4), 605-617, 2005 | 605 | 2005 |
A novel multiple-stage antimalarial agent that inhibits protein synthesis B Baragaña, I Hallyburton, MCS Lee, NR Norcross, R Grimaldi, TD Otto, ... Nature 522 (7556), 315-320, 2015 | 434 | 2015 |
Targeting Plasmodium PI(4)K to eliminate malaria CW McNamara, MCS Lee, CS Lim, SH Lim, J Roland, A Nagle, O Simon, ... Nature 504 (7479), 248-253, 2013 | 433 | 2013 |
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery S Meister, DM Plouffe, KL Kuhen, GMC Bonamy, T Wu, SW Barnes, ... Science 334 (6061), 1372-1377, 2011 | 367 | 2011 |
Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue SH Adjalley, GL Johnston, T Li, RT Eastman, EH Ekland, AG Eappen, ... Proceedings of the National Academy of Sciences 108 (47), E1214-E1223, 2011 | 335 | 2011 |
(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium MB Jiménez-Díaz, D Ebert, Y Salinas, A Pradhan, AM Lehane, ... Proceedings of the National Academy of Sciences 111 (50), E5455-E5462, 2014 | 259 | 2014 |
Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase T Paquet, C Le Manach, DG Cabrera, Y Younis, PP Henrich, TS Abraham, ... Science translational medicine 9 (387), eaad9735, 2017 | 243 | 2017 |
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics AN Cowell, ES Istvan, AK Lukens, MG Gomez-Lorenzo, M Vanaerschot, ... Science 359 (6372), 191-199, 2018 | 217 | 2018 |
Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases J Straimer, MCS Lee, AH Lee, B Zeitler, AE Williams, JR Pearl, L Zhang, ... Nature methods 9 (10), 993-998, 2012 | 202 | 2012 |
Profiling the Essential Nature of Lipid Metabolism in Asexual Blood and Gametocyte Stages of Plasmodium falciparum S Gulati, EH Ekland, KV Ruggles, RB Chan, B Jayabalasingham, B Zhou, ... Cell Host & Microbe 18 (3), 371-381, 2015 | 170 | 2015 |
KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission KL Kuhen, AK Chatterjee, M Rottmann, K Gagaring, R Borboa, ... Antimicrobial agents and chemotherapy 58 (9), 5060-5067, 2014 | 163 | 2014 |
Ceramide biosynthesis is required for the formation of the oligomeric H+-ATPase Pma1p in the yeast endoplasmic reticulum MCS Lee, S Hamamoto, R Schekman Journal of Biological Chemistry 277 (25), 22395-22401, 2002 | 156 | 2002 |
Proteinase inhibitors from Nicotiana alata enhance plant resistance to insect pests RL Heath, G McDonald, JT Christeller, M Lee, K Bateman, J West, ... Journal of Insect Physiology 43 (9), 833-842, 1997 | 138 | 1997 |
Molecular mechanisms of COPII vesicle formation MCS Lee, EA Miller Seminars in cell & developmental biology 18 (4), 424-434, 2007 | 121 | 2007 |
A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue E Sonoiki, CL Ng, MCS Lee, D Guo, YK Zhang, Y Zhou, MRK Alley, ... Nature communications 8 (1), 1-11, 2017 | 120 | 2017 |
A broad analysis of resistance development in the malaria parasite VC Corey, AK Lukens, ES Istvan, MCS Lee, V Franco, P Magistrado, ... Nature communications 7 (1), 1-9, 2016 | 115 | 2016 |
UDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genes MYX Lim, G LaMonte, MCS Lee, C Reimer, BH Tan, V Corey, BF Tjahjadi, ... Nature microbiology 1 (12), 1-12, 2016 | 112 | 2016 |