A statistical thermodynamic model of the protein ensemble VJ Hilser, B García-Moreno E, TG Oas, G Kapp, ST Whitten Chemical reviews 106 (5), 1545-1558, 2006 | 231 | 2006 |
Local conformational fluctuations can modulate the coupling between proton binding and global structural transitions in proteins ST Whitten, B García-Moreno E, VJ Hilser Proceedings of the National Academy of Sciences 102 (12), 4282-4287, 2005 | 192 | 2005 |
pH dependence of stability of staphylococcal nuclease: evidence of substantial electrostatic interactions in the denatured state ST Whitten, B García-Moreno E Biochemistry 39 (46), 14292-14304, 2000 | 179 | 2000 |
The role of protein conformational fluctuations in allostery, function, and evolution JO Wrabl, J Gu, T Liu, TP Schrank, ST Whitten, VJ Hilser Biophysical chemistry 159 (1), 129-141, 2011 | 126 | 2011 |
Functional residues serve a dominant role in mediating the cooperativity of the protein ensemble T Liu, ST Whitten, VJ Hilser Proceedings of the National Academy of Sciences 104 (11), 4347-4352, 2007 | 88 | 2007 |
Low pH immobilizes and kills human leukocytes and prevents transmission of cell-associated HIV in a mouse model SS Olmsted, KV Khanna, EM Ng, ST Whitten, ON Johnson, RB Markham, ... BMC infectious diseases 5, 1-9, 2005 | 69 | 2005 |
The origin of pH-dependent changes in m-values for the denaturant-induced unfolding of proteins ST Whitten, JO Wooll, R Razeghifard, EB Garcı́a-Moreno, VJ Hilser Journal of molecular biology 309 (5), 1165-1175, 2001 | 68 | 2001 |
Ensemble‐based signatures of energy propagation in proteins: A new view of an old phenomenon T Liu, ST Whitten, VJ Hilser Proteins: Structure, Function, and Bioinformatics 62 (3), 728-738, 2006 | 62 | 2006 |
COREX/BEST server: a web browser-based program that calculates regional stability variations within protein structures J Vertrees, P Barritt, S Whitten, VJ Hilser Bioinformatics 21 (15), 3318-3319, 2005 | 61 | 2005 |
Thermodynamic mechanism and consequences of the polyproline II (PII) structural bias in the denatured states of proteins JB Hamburger, JC Ferreon, ST Whitten, VJ Hilser Biochemistry 43 (30), 9790-9799, 2004 | 54 | 2004 |
Temperature effects on the hydrodynamic radius of the intrinsically disordered N‐terminal region of the p53 protein TD Langridge, MJ Tarver, ST Whitten Proteins: Structure, Function, and Bioinformatics 82 (4), 668-678, 2014 | 53 | 2014 |
Revealing the nature of the native state ensemble through cold denaturation ST Whitten, AJ Kurtz, MS Pometun, AJ Wand, VJ Hilser Biochemistry 45 (34), 10163-10174, 2006 | 51 | 2006 |
Molecular mechanisms of pH‐driven conformational transitions of proteins: Insights from continuum electrostatics calculations of acid unfolding CA Fitch, ST Whitten, VJ Hilser, B García‐Moreno E Proteins: Structure, Function, and Bioinformatics 63 (1), 113-126, 2006 | 45 | 2006 |
Hydrodynamic radii of intrinsically disordered proteins determined from experimental polyproline II propensities ME Tomasso, MJ Tarver, D Devarajan, ST Whitten PLoS computational biology 12 (1), e1004686, 2016 | 44 | 2016 |
Fungal metabolite ophiobolin A as a promising anti-glioma agent: In vivo evaluation, structure–activity relationship and unique pyrrolylation of primary amines R Dasari, M Masi, R Lisy, M Ferdérin, LR English, A Cimmino, V Mathieu, ... Bioorganic & medicinal chemistry letters 25 (20), 4544-4548, 2015 | 40 | 2015 |
Alanine and proline content modulate global sensitivity to discrete perturbations in disordered proteins RB Perez, A Tischer, M Auton, ST Whitten Proteins: Structure, Function, and Bioinformatics 82 (12), 3373-3384, 2014 | 35 | 2014 |
The proline/glycine-rich region of the biofilm adhesion protein Aap forms an extended stalk that resists compaction AE Yarawsky, LR English, ST Whitten, AB Herr Journal of molecular biology 429 (2), 261-279, 2017 | 28 | 2017 |
Denatured-state energy landscapes of a protein structural database reveal the energetic determinants of a framework model for folding S Wang, J Gu, SA Larson, ST Whitten, VJ Hilser Journal of molecular biology 381 (5), 1184-1201, 2008 | 27 | 2008 |
Exploring the impact of polyproline II (PII) conformational bias on the binding of peptides to the SEM‐5 SH3 domain ST Whitten, HW Yang, RO Fox, VJ Hilser Protein Science 17 (7), 1200-1211, 2008 | 27 | 2008 |
Intrinsic α helix propensities compact hydrodynamic radii in intrinsically disordered proteins LR English, EC Tilton, BJ Ricard, ST Whitten Proteins: Structure, Function, and Bioinformatics 85 (2), 296-311, 2017 | 22 | 2017 |