| Combined treatment with bortezomib plus bafilomycin A1 enhances the cytocidal effect and induces endoplasmic reticulum stress in U266 myeloma cells: crosstalk among proteasome … T Kawaguchi, K Miyazawa, S Moriya, T Ohtomo, XF Che, M Naito, M Itoh, ... International journal of oncology 38 (3), 643-654, 2011 | 135 | 2011 |
| Macrolide antibiotics block autophagy flux and sensitize to bortezomib via endoplasmic reticulum stress-mediated CHOP induction in myeloma cells S Moriya, XF Che, S Komatsu, A Abe, T Kawaguchi, A Gotoh, M Inazu, ... International journal of oncology 42 (5), 1541-1550, 2013 | 105 | 2013 |
| EGFR-independent autophagy induction with gefitinib and enhancement of its cytotoxic effect by targeting autophagy with clarithromycin in non-small cell lung cancer cells S Sugita, K Ito, Y Yamashiro, S Moriya, XF Che, T Yokoyama, M Hiramoto, ... Biochemical and biophysical research communications 461 (1), 28-34, 2015 | 70 | 2015 |
| The β-carboline alkaloid harmol induces cell death via autophagy but not apoptosis in human non-small cell lung cancer A549 cells A Abe, H Yamada, S Moriya, K Miyazawa Biological and Pharmaceutical Bulletin 34 (8), 1264-1272, 2011 | 63 | 2011 |
| Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines S Mukai, S Moriya, M Hiramoto, H Kazama, H Kokuba, XF Che, ... International journal of oncology 48 (1), 45-54, 2016 | 55 | 2016 |
| Targeting the integrated networks of aggresome formation, proteasome, and autophagy potentiates ER stress‑mediated cell death in multiple myeloma cells S Moriya, S Komatsu, K Yamasaki, Y Kawai, H Kokuba, A Hirota, XF Che, ... International journal of oncology 46 (2), 474-486, 2015 | 54 | 2015 |
| Clarithromycin enhances bortezomib-induced cytotoxicity via endoplasmic reticulum stress-mediated CHOP (GADD153) induction and autophagy in breast cancer cells S Komatsu, K Miyazawa, S Moriya, A Takase, M Naito, M Inazu, N Kohno, ... International journal of oncology 40 (4), 1029-1039, 2012 | 53 | 2012 |
| Abemaciclib induces atypical cell death in cancer cells characterized by formation of cytoplasmic vacuoles derived from lysosomes H Hino, N Iriyama, H Kokuba, H Kazama, S Moriya, N Takano, ... Cancer science 111 (6), 2132-2145, 2020 | 52 | 2020 |
| Combined treatment with SAHA, bortezomib, and clarithromycin for concomitant targeting of aggresome formation and intracellular proteolytic pathways enhances ER stress-mediated … S Komatsu, S Moriya, XF Che, T Yokoyama, N Kohno, K Miyazawa Biochemical and biophysical research communications 437 (1), 41-47, 2013 | 48 | 2013 |
| The cyclin-dependent kinase 4/6 inhibitor, abemaciclib, exerts dose-dependent cytostatic and cytocidal effects and induces autophagy in multiple myeloma cells N Iriyama, H Hino, S Moriya, M Hiramoto, Y Hatta, M Takei, K Miyazawa Leukemia & lymphoma 59 (6), 1439-1450, 2018 | 43 | 2018 |
| Comparison of autophagy inducibility in various tyrosine kinase inhibitors and their enhanced cytotoxicity via inhibition of autophagy in cancer cells in combined treatment … H Tanaka, H Hino, S Moriya, H Kazama, M Miyazaki, N Takano, ... Biochemistry and biophysics reports 22, 100750, 2020 | 29 | 2020 |
| Involvement of endoplasmic reticulum stress-mediated CHOP (GADD153) induction in the cytotoxicity of 2-aminophenoxazine-3-one in cancer cells S Moriya, K Miyazawa, T Kawaguchi, XF Che, A Tomoda International journal of oncology 39 (4), 981-988, 2011 | 28 | 2011 |
| Vitamin K2 induces non-apoptotic cell death along with autophagosome formation in breast cancer cell lines S Miyazawa, S Moriya, H Kokuba, H Hino, N Takano, K Miyazawa Breast Cancer 27, 225-235, 2020 | 27 | 2020 |
| Azithromycin enhances the cytotoxicity of DNA‐damaging drugs via lysosomal membrane permeabilization in lung cancer cells K Toriyama, N Takano, H Kokuba, H Kazama, S Moriya, M Hiramoto, ... Cancer Science 112 (8), 3324-3337, 2021 | 26 | 2021 |
| Targeting bortezomib-induced aggresome formation using vinorelbine enhances the cytotoxic effect along with ER stress loading in breast cancer cell lines K Miyahara, H Kazama, H Kokuba, S Komatsu, A Hirota, J Takemura, ... International Journal of Oncology 49 (5), 1848-1858, 2016 | 24 | 2016 |
| Cytoprotective effect of imatinib mesylate in non-BCR-ABL-expressing cells along with autophagosome formation T Ohtomo, K Miyazawa, M Naito, S Moriya, M Kuroda, M Itoh, A Tomoda Biochemical and biophysical research communications 391 (1), 310-315, 2010 | 22 | 2010 |
| Macrolide antibiotics exhibit cytotoxic effect under amino acid-depleted culture condition by blocking autophagy flux in head and neck squamous cell carcinoma cell lines K Hirasawa, S Moriya, K Miyahara, H Kazama, A Hirota, J Takemura, ... PLoS One 11 (12), e0164529, 2016 | 20 | 2016 |
| Visualization of ceramide channels in lysosomes following endogenous palmitoyl-ceramide accumulation as an initial step in the induction of necrosis M Yamane, S Moriya, H Kokuba Biochemistry and Biophysics Reports 11, 174-181, 2017 | 19 | 2017 |
| D, L-Threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (DL-PDMP) increases endoplasmic reticulum stress, autophagy and apoptosis accompanying ceramide accumulation via … M Yamane, K Miyazawa, S Moriya, A Abe, S Yamane Biochimie 93 (9), 1446-1459, 2011 | 18 | 2011 |
| Macrolide antibiotics enhance the antitumor effect of lansoprazole resulting in lysosomal membrane permeabilization‑associated cell death A Takeda, N Takano, H Kokuba, H Hino, S Moriya, A Abe, M Hiramoto, ... International Journal of Oncology 57 (6), 1280-1292, 2020 | 17 | 2020 |
