Clues to the pathogenesis of familial colorectal cancer LA Aaltonen, P Peltomäki, FS Leach, P Sistonen, L Pylkkänen, JP Mecklin, ... Science 260 (5109), 812-816, 1993 | 3617 | 1993 |
Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer FS Leach, NC Nicolaides, N Papadopoulos, B Liu, J Jen, R Parsons, ... Cell 75 (6), 1215-1225, 1993 | 2938 | 1993 |
Detection and localization of surgically resectable cancers with a multi-analyte blood test JD Cohen, L Li, Y Wang, C Thoburn, B Afsari, L Danilova, C Douville, ... Science 359 (6378), 926-930, 2018 | 2504 | 2018 |
The molecular basis of Turcot's syndrome SR Hamilton, B Liu, RE Parsons, N Papadopoulos, J Jen, SM Powell, ... New England Journal of Medicine 332 (13), 839-847, 1995 | 1461 | 1995 |
Hypermutability and mismatch repair deficiency in RER+ tumor cells R Parsons, GM Li, MJ Longley, W Fang, N Papadopoulos, J Jen, ... Cell 75 (6), 1227-1236, 1993 | 1376 | 1993 |
Facile detection of mitochondrial DNA mutations in tumors and bodily fluids MS Fliss, H Usadel, OL Caballero, L Wu, MR Buta, SM Eleff, J Jen, ... Science 287 (5460), 2017-2019, 2000 | 1075 | 2000 |
Frequent Inactivation of PTEN/MMAC1 in Primary Prostate Cancer P Cairns, K Okami, S Halachmi, N Halachmi, M Esteller, JG Herman, ... Cancer research 57 (22), 4997-5000, 1997 | 1032 | 1997 |
Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences. H Kim, J Jen, B Vogelstein, SR Hamilton The American journal of pathology 145 (1), 148, 1994 | 1015 | 1994 |
Analysis of human transcriptomes VE Velculescu, SL Madden, L Zhang, AE Lash, J Yu, C Rago, A Lal, ... Nature genetics 23 (4), 387-388, 1999 | 992 | 1999 |
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability B Liu, NC Nicolaides, S Markowitz, JKV Willson, RE Parsons, J Jen, ... Nature genetics 9 (1), 48-55, 1995 | 972 | 1995 |
Molecular diagnosis of familial adenomatous polyposis SM Powell, GM Petersen, AJ Krush, S Booker, J Jen, FM Giardiello, ... New England Journal of Medicine 329 (27), 1982-1987, 1993 | 948 | 1993 |
Allelic loss of chromosome 18q and prognosis in colorectal cancer J Jen, H Kim, S Piantadosi, ZF Liu, RC Levitt, P Sistonen, KW Kinzler, ... New England Journal of Medicine 331 (4), 213-221, 1994 | 934 | 1994 |
Hypermethylation-associated Inactivation Indicates a Tumor Suppressor Role for p15INK4B JG Herman, J Jen, A Merlo, SB Baylin Cancer research 56 (4), 722-727, 1996 | 836 | 1996 |
Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival MT Landi, T Dracheva, M Rotunno, JD Figueroa, H Liu, A Dasgupta, ... PloS one 3 (2), e1651, 2008 | 765 | 2008 |
Molecular determinants of dysplasia in colorectal lesions J Jen, SM Powell, N Papadopoulos, KJ Smith, SR Hamilton, B Vogelstein, ... Cancer research 54 (21), 5523-5526, 1994 | 723 | 1994 |
Gene promoter hypermethylation in tumors and serum of head and neck cancer patients M Sanchez-Cespedes, M Esteller, L Wu, H Nawroz-Danish, GH Yoo, ... Cancer research 60 (4), 892-895, 2000 | 716 | 2000 |
MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers M Seike, A Goto, T Okano, ED Bowman, AJ Schetter, I Horikawa, ... Proceedings of the National Academy of Sciences 106 (29), 12085-12090, 2009 | 688 | 2009 |
Deletion of p16 and p15 Genes in Brain Tumors J Jen, JW Harper, SH Bigner, DD Bigner, N Papadopoulos, S Markowitz, ... Cancer research 54 (24), 6353-6358, 1994 | 662 | 1994 |
AIS is an oncogene amplified in squamous cell carcinoma K Hibi, B Trink, M Patturajan, WH Westra, OL Caballero, DE Hill, ... Proceedings of the National Academy of Sciences 97 (10), 5462-5467, 2000 | 647 | 2000 |
Promoter Hypermethylation Patterns of p16, O6-Methylguanine-DNA-methyltransferase, and Death-associated Protein Kinase in Tumors and Saliva of Head … SLB Rosas, W Koch, MGC Carvalho, L Wu, J Califano, W Westra, J Jen, ... Cancer research 61 (3), 939-942, 2001 | 513 | 2001 |