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Michael Milburn
Michael Milburn
Chief Executive Officer, GeneCentric Therapeutics
Verified email at genecentric.com
Title
Cited by
Cited by
Year
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ
RT Nolte, GB Wisely, S Westin, JE Cobb, MH Lambert, R Kurokawa, ...
Nature 395 (6698), 137-143, 1998
24501998
Molecular recognition of fatty acids by peroxisome proliferator–activated receptors
HE Xu, MH Lambert, VG Montana, DJ Parks, SG Blanchard, PJ Brown, ...
Molecular cell 3 (3), 397-403, 1999
15001999
Molecular Switch for Signal Transduction: Structural Differences Between Active and Inactive Forms of Protooncogenic ras Proteins
MV Milburn, L Tong, AM DeVos, A Brünger, Z Yamaizumi, S Nishimura, ...
Science 247 (4945), 939-945, 1990
13991990
An atlas of genetic influences on human blood metabolites
SY Shin, EB Fauman, AK Petersen, J Krumsiek, R Santos, J Huang, ...
Nature genetics 46 (6), 543-550, 2014
12742014
Human metabolic individuality in biomedical and pharmaceutical research
K Suhre, SY Shin, AK Petersen, RP Mohney, D Meredith, B Wägele, ...
Nature 477 (7362), 54-60, 2011
10942011
Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation
EM McInerney, DW Rose, SE Flynn, S Westin, TM Mullen, A Krones, ...
Genes & development 12 (21), 3357-3368, 1998
7501998
Asymmetry in the PPARγ/RXRα crystal structure reveals the molecular basis of heterodimerization among nuclear receptors
RT Gampe, VG Montana, MH Lambert, AB Miller, RK Bledsoe, MV Milburn, ...
Molecular cell 5 (3), 545-555, 2000
7412000
Three-Dimensional Structure of an Oncogene Protein: Catalytic Domain of Human c-H-ras P21
AM De Vos, L Tong, MV Milburn, PM Matias, J Jancarik, S Noguchi, ...
Science 239 (4842), 888-893, 1988
6621988
Metabolic footprint of diabetes: a multiplatform metabolomics study in an epidemiological setting
K Suhre, C Meisinger, A Döring, E Altmaier, P Belcredi, C Gieger, ...
PloS one 5 (11), e13953, 2010
6612010
Molecular determinants of nuclear receptor–corepressor interaction
V Perissi, LM Staszewski, EM McInerney, R Kurokawa, A Krones, ...
Genes & development 13 (24), 3198-3208, 1999
6261999
α-Hydroxybutyrate is an early biomarker of insulin resistance and glucose intolerance in a nondiabetic population
WE Gall, K Beebe, KA Lawton, KP Adam, MW Mitchell, PJ Nakhle, ...
PloS one 5 (5), e10883, 2010
6212010
Three-dimensional structures of the ligand-binding domain of the bacterial aspartate receptor with and without a ligand
MV Milburn, GG Privé, DL Milligan, WG Scott, J Yeh, J Jancarik, ...
Science 254 (5036), 1342-1347, 1991
5421991
Analysis of the adult human plasma metabolome
KA Lawton, A Berger, M Mitchell, KE Milgram, AM Evans, L Guo, ...
Future Medicine Ltd 9 (4), 383-397, 2008
4992008
A peroxisome proliferator-activated receptor γ ligand inhibits adipocyte differentiation
JL Oberfield, JL Collins, CP Holmes, DM Goreham, JP Cooper, JE Cobb, ...
Proceedings of the National Academy of Sciences 96 (11), 6102-6106, 1999
4541999
Structural basis for the activity of drugs that inhibit phosphodiesterases
GL Card, BP England, Y Suzuki, D Fong, B Powell, B Lee, C Luu, ...
Structure 12 (12), 2233-2247, 2004
4532004
Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity
RX Xu, AM Hassell, D Vanderwall, MH Lambert, WD Holmes, MA Luther, ...
Science 288 (5472), 1822-1825, 2000
4392000
Interactions controlling the assembly of nuclear-receptor heterodimers and co-activators
S Westin, R Kurokawa, RT Nolte, GB Wisely, EM McInerney, DW Rose, ...
Nature 395 (6698), 199-202, 1998
4331998
Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance
E Ferrannini, A Natali, S Camastra, M Nannipieri, A Mari, KP Adam, ...
Diabetes 62 (5), 1730-1737, 2013
3732013
A novel dimer configuration revealed by the crystal structure at 2.4 Å resolution of human interleukin-5
MV Milburn, AM Hassell, MH Lambert, SR Jordan, AEI Proudfoot, ...
Nature 363 (6425), 172-176, 1993
3651993
A glutamine switch mechanism for nucleotide selectivity by phosphodiesterases
KYJ Zhang, GL Card, Y Suzuki, DR Artis, D Fong, S Gillette, D Hsieh, ...
Molecular cell 15 (2), 279-286, 2004
3532004
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