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Krishna Dev Oruganty
Krishna Dev Oruganty
Principal Scientist, Flagship Pioneering
Verified email at flagshippioneering.com
Title
Cited by
Cited by
Year
Deciphering the structural basis of eukaryotic protein kinase regulation
HS Meharena, P Chang, MM Keshwani, K Oruganty, AK Nene, N Kannan, ...
PLoS biology 11 (10), e1001680, 2013
2132013
The entropic force generated by intrinsically disordered segments tunes protein function
ND Keul, K Oruganty, ETS Bergman, NR Beattie, WE McDonald, ...
Nature 563 (7732), 584-588, 2018
1302018
Mitochondrial ADCK3 Employs an Atypical Protein Kinase-like Fold to Enable Coenzyme Q Biosynthesis
JA Stefely, AG Reidenbach, A Ulbrich, K Oruganty, BJ Floyd, A Jochem, ...
Molecular cell 57 (1), 83-94, 2015
1282015
Relation extraction from clinical texts using domain invariant convolutional neural network
NG Sunil Kumar Sahu, Ashish Anand, Krishnadev Oruganty
Proceedings of the 15th Workshop on Biomedical Natural Language Processing …, 2016
123*2016
Interaction preferences across protein-protein interfaces of obligatory and non-obligatory components are different
S De, O Krishnadev, N Srinivasan, N Rekha
BMC structural biology 5 (1), 1-16, 2005
1232005
The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner
Fiona P Bailey, Dominic P Byrne, Krishnadev Oruganty, Claire E Eyers ...
Biochem. J., 2015
902015
Prediction of protein–protein interactions between human host and a pathogen and its application to three pathogenic bacteria
O Krishnadev, N Srinivasan
International journal of biological macromolecules 48 (4), 613-619, 2011
622011
Identification of a hidden strain switch provides clues to an ancient structural mechanism in protein kinases
K Oruganty, NS Talathi, ZA Wood, N Kannan
Proceedings of the National Academy of Sciences 110 (3), 924-929, 2013
462013
Design principles underpinning the regulatory diversity of protein kinases
K Oruganty, N Kannan
Philosophical Transactions of the Royal Society B: Biological Sciences 367 …, 2012
412012
A data integration approach to predict host-pathogen protein-protein interactions: application to recognize protein interactions between human and a malarial parasite
O Krishnadev, N Srinivasan
In silico biology 8 (3-4), 235-250, 2008
402008
Hydrophobic Core Variations Provide a Structural Framework for Tyrosine Kinase Evolution and Functional Specialization
SM Krishnadev Oruganty, annie Kwon, Dominic P. Byrne, Samantha Ferries ...
PLoS Genetics 12 (2), e1005885, 2016
382016
Inhibiting EGFR dimerization using triazolyl-bridged dimerization arm mimics
LE Hanold, K Oruganty, NT Ton, AM Beedle, N Kannan, EJ Kennedy
PLoS One 10 (3), e0118796, 2015
382015
Prediction of protein–protein interactions between Helicobacter pylori and a human host
N Tyagi, O Krishnadev, N Srinivasan
Molecular bioSystems 5 (12), 1630-1635, 2009
352009
MulPSSM: a database of multiple position-specific scoring matrices of protein domain families
VS Gowri, O Krishnadev, CS Swamy, N Srinivasan
Nucleic acids research 34 (suppl_1), D243-D246, 2006
352006
A graph spectral analysis of the structural similarity network of protein chains
O Krishnadev, KV Brinda, S Vishveshwara
PROTEINS: Structure, Function, and Bioinformatics 61 (1), 152-163, 2005
232005
Co-Conserved MAPK Features Couple D-Domain Docking Groove to Distal Allosteric Sites via the C-Terminal Flanking Tail
KN Nguyen T, Ruan Z, Oruganty K
PLoS One. 10 (3), e0119636, 2015
222015
Identification and classification of small molecule kinases: insights into substrate recognition and specificity
K Oruganty, EE Talevich, AF Neuwald, N Kannan
BMC evolutionary biology 16 (1), 1-14, 2016
202016
Strategies for the effective identification of remotely related sequences in multiple PSSM search approach
VS Gowri, KG Tina, O Krishnadev, N Srinivasan
Proteins: Structure, Function, and Bioinformatics 67 (4), 789-794, 2007
182007
AlignHUSH: alignment of HMMs using structure and hydrophobicity information
O Krishnadev, N Srinivasan
BMC bioinformatics 12 (1), 1-13, 2011
142011
PRODOC: a resource for the comparison of tethered protein domain architectures with in-built information on remotely related domain families
O Krishnadev, N Rekha, SB Pandit, S Abhiman, S Mohanty, LS Swapna, ...
Nucleic acids research 33 (suppl_2), W126-W129, 2005
142005
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