| W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity JD Hulzinga, L Thuneberg, M Klüppel, J Malysz, HB Mikkelsen, ... Nature 373 (6512), 347-349, 1995 | 1673 | 1995 |
| Developmental origin and kit‐dependent development of the interstitial cells of cajal in the mammalian small intestine M Klüppel, JD Huizinga, J Malysz, A Bernstein Developmental dynamics: an official publication of the American Association …, 1998 | 285 | 1998 |
| Reporter constructs with low background activity utilizing the cat gene M Boshart, M Klüppel, A Schmidt, G Schütz, B Luckow Gene 110 (1), 129-130, 1992 | 272 | 1992 |
| Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage morphogenesis M Klüppel, TN Wight, C Chan, A Hinek, JL Wrana Oxford University Press for The Company of Biologists Limited 132 (17), 3989 …, 2005 | 221 | 2005 |
| An immunological renal disease in transgenic mice that overexpress Fli-1, a member of the ets family of transcription factor genes L Zhang, A Eddy, YT Teng, M Fritzler, M Kluppel, F Melet, A Bernstein Molecular and cellular biology, 1995 | 184 | 1995 |
| Turning it up a Notch: cross‐talk between TGFβ and Notch signaling M Klüppel, JL Wrana Bioessays 27 (2), 115-118, 2005 | 156 | 2005 |
| The mouse tyrosinase promoter is sufficient for expression in melanocytes and in the pigmented epithelium of the retina. M Klüppel, F Beermann, S Ruppert, E Schmid, E Hummler, G Schütz Proceedings of the National Academy of Sciences 88 (9), 3777-3781, 1991 | 127 | 1991 |
| Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis C Xiao, J Shim, M Klüppel, SSM Zhang, C Dong, RA Flavell, XY Fu, ... Genes & development 17 (23), 2933-2949, 2003 | 120 | 2003 |
| Targeted mutations of the juxtamembrane tyrosines in the Kit receptor tyrosine kinase selectively affect multiple cell lineages Y Kimura, N Jones, M Klüppel, M Hirashima, K Tachibana, JB Cohn, ... Proceedings of the National Academy of Sciences 101 (16), 6015-6020, 2004 | 85 | 2004 |
| Chondroitin sulfate-E is a negative regulator of a pro-tumorigenic Wnt/beta-catenin-Collagen 1 axis in breast cancer cells CM Willis, M Klüppel PLoS One 9 (8), e103966, 2014 | 67 | 2014 |
| The roles of chondroitin-4-sulfotransferase-1 in development and disease M Klüppel Progress in molecular biology and translational science 93, 113-132, 2010 | 67 | 2010 |
| Long-range genomic rearrangements upstream of Kit dysregulate the developmental pattern of Kit expression in W 57 and W banded mice … M Klüppel, DL Nagle, M Bucan, A Bernstein Development 124 (1), 65-77, 1997 | 61 | 1997 |
| Aquarius, a novel gene isolated by gene trapping with an RNA‐dependent RNA polymerase motif M Sam, W Wurst, M Klüppel, O Jin, H Heng, A Bernstein Developmental dynamics: an official publication of the American Association …, 1998 | 48 | 1998 |
| Myocardial storage of chondroitin sulfate‐containing moieties in Costello syndrome patients with severe hypertrophic cardiomyopathy A Hinek, MA Teitell, L Schoyer, W Allen, KW Gripp, R Hamilton, ... American journal of medical genetics Part A 133 (1), 1-12, 2005 | 47 | 2005 |
| Elimination of breast tumor-associated chondroitin sulfate promotes metastasis RD Prinz, CM Willis, A Viloria-Petit, M Klüppel Genet Mol Res 10 (4), 3901-3913, 2011 | 45 | 2011 |
| A high-throughput induction gene trap approach defines C4ST as a target of BMP signaling M Klüppel, KA Vallis, JL Wrana Mechanisms of development 118 (1-2), 77-89, 2002 | 40 | 2002 |
| Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/β-catenin signaling RD Prinz, CM Willis, TH Van Kuppevelt, M Klüppel PloS one 9 (3), e92381, 2014 | 39 | 2014 |
| C4ST-1/CHST11-controlled chondroitin sulfation interferes with oncogenic HRAS signaling in Costello syndrome M Klüppel, P Samavarchi-Tehrani, K Liu, JL Wrana, A Hinek European journal of human genetics 20 (8), 870-877, 2012 | 29 | 2012 |
| Inhibition by chondroitin sulfate E can specify functional Wnt/β-catenin signaling thresholds in NIH3T3 fibroblasts CM Willis, M Klüppel Journal of Biological Chemistry 287 (44), 37042-37056, 2012 | 25 | 2012 |
| Identification and characterization of TGFbeta-dependent and-independent cis-regulatory modules in the C4ST-1/CHST11 locus CM Willis, JL Wrana, M Klüppel Genet Mol Res 8 (4), 1331-43, 2009 | 18 | 2009 |
