Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKBβ) H Cho, J Mu, JK Kim, JL Thorvaldsen, Q Chu, EB Crenshaw III, ... Science 292 (5522), 1728-1731, 2001 | 2380 | 2001 |
Unified nomenclature for the winged helix/forkhead transcription factors KH Kaestner, W Knöchel, DE Martínez Genes & development 14 (2), 142-146, 2000 | 1548 | 2000 |
DNA binding of the glucocorticoid receptor is not essential for survival HM Reichardt, KH Kaestner, J Tuckermann, O Kretz, O Wessely, R Bock, ... Cell 93 (4), 531-541, 1998 | 1368 | 1998 |
Cytoplasmic chromatin triggers inflammation in senescence and cancer Z Dou, K Ghosh, MG Vizioli, J Zhu, P Sen, KJ Wangensteen, J Simithy, ... Nature 550 (7676), 402-406, 2017 | 1145 | 2017 |
Krüppel-like factor 4 regulates macrophage polarization X Liao, N Sharma, F Kapadia, G Zhou, Y Lu, H Hong, K Paruchuri, ... The Journal of clinical investigation 121 (7), 2736-2749, 2011 | 833 | 2011 |
KLF family members regulate intrinsic axon regeneration ability DL Moore, MG Blackmore, Y Hu, KH Kaestner, JL Bixby, VP Lemmon, ... Science 326 (5950), 298-301, 2009 | 799 | 2009 |
The evolution of Fox genes and their role in development and disease S Hannenhalli, KH Kaestner Nature Reviews Genetics 10 (4), 233-240, 2009 | 779 | 2009 |
Hepatocyte nuclear factor 4α controls the development of a hepatic epithelium and liver morphogenesis F Parviz, C Matullo, WD Garrison, L Savatski, JW Adamson, G Ning, ... Nature genetics 34 (3), 292-296, 2003 | 731 | 2003 |
The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon JP Katz, N Perreault, BG Goldstein, CS Lee, PA Labosky, VW Yang, ... Oxford University Press for The Company of Biologists Limited 129 (11), 2619 …, 2002 | 725 | 2002 |
The initiation of liver development is dependent on Foxa transcription factors CS Lee, JR Friedman, JT Fulmer, KH Kaestner Nature 435 (7044), 944-947, 2005 | 686 | 2005 |
Severe impairment of permatogenesis in mice lacking the CREM gene JA Blendy, KH Kaestner, GF Weinbauer, E Nieschlag, G Schütz Nature 380 (6570), 162-165, 1996 | 661 | 1996 |
Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 a, P and 7 genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm AP Monaghan, KH Kaestner, E Grau, G Schutz Development 19, 567-78, 1993 | 634* | 1993 |
Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis M Vujkovic, JM Keaton, JA Lynch, DR Miller, J Zhou, C Tcheandjieu, ... Nature genetics 52 (7), 680-691, 2020 | 604 | 2020 |
The Foxa family of transcription factors in development and metabolism JR Friedman, KH Kaestner Cellular and Molecular Life Sciences CMLS 63, 2317-2328, 2006 | 595 | 2006 |
Cdx2 ectopic expression induces gastric intestinal metaplasia in transgenic mice DG Silberg, J Sullivan, E Kang, GP Swain, J Moffett, NJ Sund, SD Sackett, ... Gastroenterology 122 (3), 689-696, 2002 | 570 | 2002 |
CCAAT/enhancer binding protein gene promoter: binding of nuclear factors during differentiation of 3T3-L1 preadipocytes. RJ Christy, KH Kaestner, DE Geiman, MD Lane Proceedings of the National Academy of Sciences 88 (6), 2593-2597, 1991 | 522 | 1991 |
Dll1-and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells L Pellegrinet, V Rodilla, Z Liu, S Chen, U Koch, L Espinosa, KH Kaestner, ... Gastroenterology 140 (4), 1230-1240. e7, 2011 | 514 | 2011 |
Subepithelial telocytes are an important source of Wnts that supports intestinal crypts M Shoshkes-Carmel, YJ Wang, KJ Wangensteen, B Tóth, A Kondo, ... Nature 557 (7704), 242-246, 2018 | 513 | 2018 |
Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase. JM Ntambi, SA Buhrow, KH Kaestner, RJ Christy, E Sibley, TJ Kelly Jr, ... Journal of Biological Chemistry 263 (33), 17291-17300, 1988 | 488 | 1988 |
Expansion of β-cell mass in response to pregnancy S Rieck, KH Kaestner Trends in Endocrinology & Metabolism 21 (3), 151-158, 2010 | 478 | 2010 |