Samuel Deutsch
Samuel Deutsch
Nutcracker Therapeutics
Vahvistettu sähköpostiosoite verkkotunnuksessa
Chromosome 21 and down syndrome: from genomics to pathophysiology
SE Antonarakis, R Lyle, ET Dermitzakis, A Reymond, S Deutsch
Nature reviews genetics 5 (10), 725-738, 2004
Common regulatory variation impacts gene expression in a cell type–dependent manner
AS Dimas, S Deutsch, BE Stranger, SB Montgomery, C Borel, ...
Science 325 (5945), 1246-1250, 2009
Genome-wide associations of gene expression variation in humans
BE Stranger, MS Forrest, AG Clark, MJ Minichiello, S Deutsch, R Lyle, ...
PLoS genetics 1 (6), e78, 2005
Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3′ untranslated region: a mechanism for functional single-nucleotide …
P Sethupathy, C Borel, M Gagnebin, GR Grant, S Deutsch, TS Elton, ...
The American Journal of Human Genetics 81 (2), 405-413, 2007
Genetic structure of Europeans: a view from the North–East
M Nelis, T Esko, R Mägi, F Zimprich, A Zimprich, D Toncheva, ...
PloS one 4 (5), e5472, 2009
Methane yield phenotypes linked to differential gene expression in the sheep rumen microbiome
W Shi, CD Moon, SC Leahy, D Kang, J Froula, S Kittelmann, C Fan, ...
Genome research 24 (9), 1517-1525, 2014
Domains of genome-wide gene expression dysregulation in Down’s syndrome
A Letourneau, FA Santoni, X Bonilla, MR Sailani, D Gonzalez, J Kind, ...
Nature 508 (7496), 345-350, 2014
Numerous potentially functional but non-genic conserved sequences on human chromosome 21
ET Dermitzakis, A Reymond, R Lyle, N Scamuffa, C Ucla, S Deutsch, ...
Nature 420 (6915), 578-582, 2002
Polymorphisms in the low-density lipoprotein receptor–related protein 5 (LRP5) gene are associated with variation in vertebral bone mass, vertebral bone size, and stature in whites
SL Ferrari, S Deutsch, U Choudhury, T Chevalley, JP Bonjour, ...
The American Journal of Human Genetics 74 (5), 866-875, 2004
Natural gene-expression variation in Down syndrome modulates the outcome of gene-dosage imbalance
P Prandini, S Deutsch, R Lyle, M Gagnebin, CD Vivier, M Delorenzi, ...
The American Journal of Human Genetics 81 (2), 252-263, 2007
Gene expression from the aneuploid chromosome in a trisomy mouse model of down syndrome
R Lyle, C Gehrig, C Neergaard-Henrichsen, S Deutsch, SE Antonarakis
Genome research 14 (7), 1268-1274, 2004
DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome
C Canzonetta, C Mulligan, S Deutsch, S Ruf, A O'Doherty, R Lyle, C Borel, ...
The American Journal of Human Genetics 83 (3), 388-400, 2008
SAR11 bacteria linked to ocean anoxia and nitrogen loss
D Tsementzi, J Wu, S Deutsch, S Nath, LM Rodriguez-R, AS Burns, ...
Nature 536 (7615), 179-183, 2016
Gene expression variation and expression quantitative trait mapping of human chromosome 21 genes
S Deutsch, R Lyle, ET Dermitzakis, H Attar, L Subrahmanyan, C Gehrig, ...
Human molecular genetics 14 (23), 3741-3749, 2005
Lessons from Two Design–Build–Test–Learn Cycles of Dodecanol Production in Escherichia coli Aided by Machine Learning
P Opgenorth, Z Costello, T Okada, G Goyal, Y Chen, J Gin, V Benites, ...
ACS synthetic biology 8 (6), 1337-1351, 2019
A new mouse model for the trisomy of the Abcg1U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome
PL Pereira, L Magnol, I Sahun, V Brault, A Duchon, P Prandini, A Gruart, ...
Human molecular genetics 18 (24), 4756-4769, 2009
Detection of aneuploidies by paralogous sequence quantification
S Deutsch, U Choudhury, G Merla, C Howald, A Sylvan, SE Antonarakis
Journal of medical genetics 41 (12), 908-915, 2004
Chemical synthesis rewriting of a bacterial genome to achieve design flexibility and biological functionality
JE Venetz, L Del Medico, A Wölfle, P Schächle, Y Bucher, D Appert, ...
Proceedings of the National Academy of Sciences 116 (16), 8070-8079, 2019
CRAGE enables rapid activation of biosynthetic gene clusters in undomesticated bacteria
G Wang, Z Zhao, J Ke, Y Engel, YM Shi, D Robinson, K Bingol, Z Zhang, ...
Nature microbiology 4 (12), 2498-2510, 2019
Knobloch syndrome: Novel mutations in COL18A1, evidence for genetic heterogeneity, and a functionally impaired polymorphism in endostatin
O Menzel, RCJ Bekkeheien, A Reymond, N Fukai, E Boye, G Kosztolanyi, ...
Human mutation 23 (1), 77-84, 2004
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Artikkelit 1–20