C. Dirk Keene, MD, PhD
C. Dirk Keene, MD, PhD
Nancy and Buster Alvord Endowed Chair and Director of Neuropathology, University of Washington
Vahvistettu sähköpostiosoite verkkotunnuksessa uw.edu - Kotisivu
Nimike
Viittaukset
Viittaukset
Vuosi
Pluripotency of mesenchymal stem cells derived from adult marrow
Y Jiang, BN Jahagirdar, RL Reinhardt, RE Schwartz, CD Keene, ...
Nature 418 (6893), 41-49, 2002
77182002
Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats
LR Zhao, WM Duan, M Reyes, CD Keene, C Verfaillie, WC Low
Experimental neurology 174 (1), 11-20, 2002
11822002
The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy
AC McKee, NJ Cairns, DW Dickson, RD Folkerth, CD Keene, I Litvan, ...
Acta neuropathologica 131 (1), 75-86, 2016
4782016
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ...
Nature genetics 49 (9), 1373-1384, 2017
3682017
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
3282019
TREM2 haplodeficiency in mice and humans impairs the microglia barrier function leading to decreased amyloid compaction and severe axonal dystrophy
P Yuan, C Condello, CD Keene, Y Wang, TD Bird, SM Paul, W Luo, ...
Neuron 90 (4), 724-739, 2016
2762016
Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease
CD Keene, CMP Rodrigues, T Eich, MS Chhabra, CJ Steer, WC Low
Proceedings of the National Academy of Sciences 99 (16), 10671-10676, 2002
2622002
Association of traumatic brain injury with late-life neurodegenerative conditions and neuropathologic findings
PK Crane, LE Gibbons, K Dams-O’Connor, E Trittschuh, JB Leverenz, ...
JAMA neurology 73 (9), 1062-1069, 2016
2032016
Highly resolved in vivo 1H NMR spectroscopy of the mouse brain at 9.4 T
I Tkáč, PG Henry, P Andersen, CD Keene, WC Low, R Gruetter
Magnetic Resonance in Medicine: An Official Journal of the International …, 2004
2022004
Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis
DJ Irwin, M Grossman, D Weintraub, HI Hurtig, JE Duda, SX Xie, EB Lee, ...
The Lancet Neurology 16 (1), 55-65, 2017
1962017
Conserved cell types with divergent features in human versus mouse cortex
RD Hodge, TE Bakken, JA Miller, KA Smith, ER Barkan, LT Graybuck, ...
Nature 573 (7772), 61-68, 2019
1792019
Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report
PT Nelson, DW Dickson, JQ Trojanowski, CR Jack, PA Boyle, K Arfanakis, ...
Brain 142 (6), 1503-1527, 2019
1652019
Thymidine analogs are transferred from prelabeled donor to host cells in the central nervous system after transplantation: a word of caution
TC Burns, XR Ortiz‐González, M Gutiérrez‐Pérez, CD Keene, R Sharda, ...
Stem cells 24 (4), 1121-1127, 2006
1602006
Orbital neoplasms in adults: clinical, radiologic, and pathologic review
TD Tailor, D Gupta, RW Dalley, CD Keene, Y Anzai
Radiographics 33 (6), 1739-1758, 2013
1422013
Neural differentiation and incorporation of bone marrow-derived multipotent adult progenitor cells after single cell transplantation into blastocyst stage mouse embryos
CD Keene, XR Ortiz-Gonzalez, Y Jiang, DA Largaespada, CM Verfaillie, ...
Cell transplantation 12 (3), 201-213, 2003
1392003
Tauroursodeoxycholic acid partially prevents apoptosis induced by 3‐nitropropionic acid: evidence for a mitochondrial pathway independent of the permeability transition
CMP Rodrigues, CL Stieers, CD Keene, X Ma, BT Kren, WC Low, ...
Journal of neurochemistry 75 (6), 2368-2379, 2000
1212000
Neural transplantation in Huntington disease: long-term grafts in two patients
CD Keene, JA Sonnen, PD Swanson, O Kopyov, JB Leverenz, TD Bird, ...
Neurology 68 (24), 2093-2098, 2007
1152007
A bile acid protects against motor and cognitive deficits and reduces striatal degeneration in the 3-nitropropionic acid model of Huntington's disease
CD Keene, CMP Rodrigues, T Eich, C Linehan-Stieers, A Abt, BT Kren, ...
Experimental neurology 171 (2), 351-360, 2001
1112001
Neurochemical changes in Huntington R6/2 mouse striatum detected by in vivo1H NMR spectroscopy
I Tkac, JM Dubinsky, CD Keene, R Gruetter, WC Low
Journal of neurochemistry 100 (5), 1397-1406, 2007
1082007
Therapeutic targets in prostaglandin E2 signaling for neurologic disease
PJ Cimino, CD Keene, RM Breyer, KS Montine, TJ Montine
Current medicinal chemistry 15 (19), 1863-1869, 2008
1052008
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Artikkelit 1–20