| N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis VC Willis, AM Gizinski, NK Banda, CP Causey, B Knuckley, KN Cordova, ... The Journal of Immunology 186 (7), 4396-4404, 2011 | 323 | 2011 |
| Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential J Jones, C Causey, B Knuckley, JL Slack-Noyes, PR Thompson Current opinion in drug discovery & development 12 (5), 616, 2009 | 269 | 2009 |
| Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor AA Chumanevich, CP Causey, BA Knuckley, JE Jones, D Poudyal, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 300 (6 …, 2011 | 217 | 2011 |
| Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3 B Knuckley, CP Causey, JE Jones, M Bhatia, CJ Dreyton, TC Osborne, ... Biochemistry 49 (23), 4852-4863, 2010 | 189 | 2010 |
| Protein arginine deiminase 4: a target for an epigenetic cancer therapy JL Slack, CP Causey, PR Thompson Cellular and Molecular Life Sciences 68, 709-720, 2011 | 128 | 2011 |
| Genome-Wide Analysis Reveals PADI4 Cooperates with Elk-1 to Activate c-Fos Expression in Breast Cancer Cells X Zhang, MJ Gamble, S Stadler, BD Cherrington, CP Causey, ... PLoS genetics 7 (6), e1002112, 2011 | 127 | 2011 |
| Identification of PADI2 as a potential breast cancer biomarker and therapeutic target JL McElwee, S Mohanan, OL Griffith, HC Breuer, LJ Anguish, ... BMC cancer 12, 1-17, 2012 | 125 | 2012 |
| Protein deiminases: new players in the developmentally regulated loss of neural regenerative ability S Lange, S Gögel, KY Leung, B Vernay, AP Nicholas, CP Causey, ... Developmental biology 355 (2), 205-214, 2011 | 123 | 2011 |
| A novel role for peptidylarginine deiminases in microvesicle release reveals therapeutic potential of PAD inhibition in sensitizing prostate cancer cells to chemotherapy S Kholia, S Jorfi, PR Thompson, CP Causey, AP Nicholas, JM Inal, ... Journal of extracellular vesicles 4 (1), 26192, 2015 | 117 | 2015 |
| Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors JE Jones, JL Slack, P Fang, X Zhang, V Subramanian, CP Causey, ... ACS chemical biology 7 (1), 160-165, 2012 | 112 | 2012 |
| A fluopol-ABPP HTS assay to identify PAD inhibitors B Knuckley, JE Jones, DA Bachovchin, J Slack, CP Causey, SJ Brown, ... Chemical communications 46 (38), 7175-7177, 2010 | 102 | 2010 |
| Citrullination of proteins: a common post-translational modification pathway induced by different nanoparticles in vitro and in vivo BM Mohamed, NK Verma, AM Davies, A McGowan, K Crosbie-Staunton, ... Nanomedicine 7 (8), 1181-1195, 2012 | 101 | 2012 |
| The development of N-α-(2-carboxyl) benzoyl-N 5-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl) benzoyl-N 5-(2-chloro-1-iminoethyl)-l-ornithine … CP Causey, JE Jones, JL Slack, D Kamei, LE Jones Jr, V Subramanian, ... Journal of medicinal chemistry 54 (19), 6919-6935, 2011 | 92 | 2011 |
| The development of N-α-(2-carboxyl) benzoyl-N 5-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl) benzoyl-N 5-(2-chloro-1-iminoethyl)-l-ornithine … CP Causey, JE Jones, JL Slack, D Kamei, LE Jones Jr, V Subramanian, ... Journal of medicinal chemistry 54 (19), 6919-6935, 2011 | 92 | 2011 |
| Anion binding by fluorescent biimidazole diamides CP Causey, WE Allen The Journal of Organic Chemistry 67 (17), 5963-5968, 2002 | 70 | 2002 |
| Haloacetamidine‐based inactivators of protein arginine deiminase 4 (PAD4): evidence that general acid catalysis promotes efficient inactivation B Knuckley, CP Causey, PJ Pellechia, PF Cook, PR Thompson Chembiochem 11 (2), 161-165, 2010 | 66 | 2010 |
| Potential role for PADI-mediated histone citrullination in preimplantation development R Kan, M Jin, V Subramanian, CP Causey, PR Thompson, SA Coonrod BMC developmental biology 12, 1-10, 2012 | 60 | 2012 |
| Molecular targeting of protein arginine deiminases to suppress colitis and prevent colon cancer EE Witalison, X Cui, CP Causey, PR Thompson, LJ Hofseth Oncotarget 6 (34), 36053, 2015 | 54 | 2015 |
| A chloroacetamidine-based inactivator of protein arginine methyltransferase 1: design, synthesis, and in vitro and in vivo evaluation O Obianyo, CP Causey, T Osborne, JE Jones, YH Lee, MR Stallcup, ... Chembiochem: a European journal of chemical biology 11 (9), 1219, 2010 | 51 | 2010 |
| Activity-based protein profiling of protein arginine methyltransferase 1 O Obianyo, CP Causey, JE Jones, PR Thompson ACS chemical biology 6 (10), 1127-1135, 2011 | 49 | 2011 |
