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Tushar Jain
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Biophysical properties of the clinical-stage antibody landscape
T Jain, T Sun, S Durand, A Hall, NR Houston, JH Nett, B Sharkey, ...
Proceedings of the National Academy of Sciences 114 (5), 944-949, 2017
4952017
Mechanical heterogeneities in model polymer glasses at small length scales
K Yoshimoto, TS Jain, KV Workum, PF Nealey, JJ de Pablo
Physical review letters 93 (17), 175501, 2004
2922004
Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool
Y Xu, W Roach, T Sun, T Jain, B Prinz, TY Yu, J Torrey, J Thomas, ...
Protein Engineering, Design & Selection 26 (10), 663-670, 2013
2162013
High-throughput screening for developability during early-stage antibody discovery using self-interaction nanoparticle spectroscopy
Y Liu, I Caffry, J Wu, SB Geng, T Jain, T Sun, F Reid, Y Cao, P Estep, Y Yu, ...
MAbs 6 (2), 483-492, 2014
1562014
Deamidation and isomerization liability analysis of 131 clinical-stage antibodies
X Lu, RP Nobrega, H Lynaugh, T Jain, K Barlow, T Boland, ...
MAbs 11 (1), 45-57, 2019
1082019
Local dynamic mechanical properties in model free-standing polymer thin films
K Yoshimoto, TS Jain, PF Nealey, JJ De Pablo
The Journal of chemical physics 122 (14), 2005
1052005
High throughput cross-interaction measures for human IgG1 antibodies correlate with clearance rates in mice
RL Kelly, T Sun, T Jain, I Caffry, Y Yu, Y Cao, H Lynaugh, M Brown, ...
MAbs 7 (4), 770-777, 2015
982015
Monte Carlo simulation of free-standing polymer films near the glass transition temperature
TS Jain, JJ de Pablo
Macromolecules 35 (6), 2167-2176, 2002
802002
Investigation of transition states in bulk and freestanding film polymer glasses
TS Jain, JJ de Pablo
Physical review letters 92 (15), 155505, 2004
762004
Density-of-states Monte Carlo simulation of a binary glass
Q Yan, TS Jain, JJ de Pablo
Physical review letters 92 (23), 235701, 2004
682004
A biased Monte Carlo technique for calculation of the density of states of polymer films
TS Jain, JJ de Pablo
The Journal of chemical physics 116 (16), 7238-7243, 2002
652002
Rapid assessment of oxidation via middle-down LCMS correlates with methionine side-chain solvent-accessible surface area for 121 clinical stage monoclonal antibodies
R Yang, T Jain, H Lynaugh, RP Nobrega, X Lu, T Boland, I Burnina, T Sun, ...
MAbs 9 (4), 646-653, 2017
582017
An alternative assay to hydrophobic interaction chromatography for high-throughput characterization of monoclonal antibodies
P Estep, I Caffry, Y Yu, T Sun, Y Cao, H Lynaugh, T Jain, M Vásquez, ...
MAbs 7 (3), 553-561, 2015
582015
Materials and methods for creating imaging layers
PF Nealey, TS Jain, EW Edwards, JJ De Pablo
US Patent 7,514,764, 2009
582009
The entropic cost of protein-protein association: a case study on acetylcholinesterase binding to fasciculin-2
DDL Minh, JM Bui, C Chang, T Jain, JMJ Swanson, JA McCammon
Biophysical journal 89 (4), L25-L27, 2005
572005
Prediction of delayed retention of antibodies in hydrophobic interaction chromatography from sequence using machine learning
T Jain, T Boland, A Lilov, I Burnina, M Brown, Y Xu, M Vásquez
Bioinformatics 33 (23), 3758-3766, 2017
472017
Configurational‐bias sampling technique for predicting side‐chain conformations in proteins
T Jain, DS Cerutti, JA McCammon
Protein Science 15 (9), 2029-2039, 2006
472006
Influence of confinement on the vibrational density of states and the Boson peak in a polymer glass
TS Jain, JJ de Pablo
The Journal of chemical physics 120 (19), 9371-9375, 2004
422004
Role of local structure on motions on the potential energy landscape for a model supercooled polymer
TS Jain, JJ de Pablo
The Journal of chemical physics 122 (17), 2005
402005
Target-independent variable region mediated effects on antibody clearance can be FcRn independent
RL Kelly, Y Yu, T Sun, I Caffry, H Lynaugh, M Brown, T Jain, Y Xu, ...
MAbs 8 (7), 1269-1275, 2016
362016
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Articles 1–20