Metabolic signature of extracellular vesicles depends on the cell culture conditions M Palviainen, H Saari, O Kärkkäinen, J Pekkinen, S Auriola, M Yliperttula, ... Journal of extracellular vesicles 8 (1), 1596669, 2019 | 34 | 2019 |
Diets rich in whole grains increase betainized compounds associated with glucose metabolism O Kärkkäinen, MA Lankinen, M Vitale, J Jokkala, J Leppänen, V Koistinen, ... The American journal of clinical nutrition 108 (5), 971-979, 2018 | 26 | 2018 |
mGluR1/5 receptor densities in the brains of alcoholic subjects: a whole-hemisphere autoradiography study J Kupila, O Kärkkäinen, V Laukkanen, E Tupala, J Tiihonen, M Storvik Psychiatry Research: Neuroimaging 212 (3), 245-250, 2013 | 25 | 2013 |
Contribution of gut microbiota to metabolism of dietary glycine betaine in mice and in vitro colonic fermentation VM Koistinen, O Kärkkäinen, K Borewicz, I Zarei, J Jokkala, V Micard, ... Microbiome 7 (1), 1-14, 2019 | 19 | 2019 |
AMPA receptors in post-mortem brains of Cloninger type 1 and 2 alcoholics: a whole-hemisphere autoradiography study O Kärkkäinen, J Kupila, M Häkkinen, V Laukkanen, E Tupala, ... Psychiatry Research: Neuroimaging 214 (3), 429-434, 2013 | 18 | 2013 |
Heart specific PGC-1α deletion identifies metabolome of cardiac restricted metabolic heart failure O Kärkkäinen, T Tuomainen, M Mutikainen, M Lehtonen, JL Ruas, ... Cardiovascular research 115 (1), 107-118, 2019 | 15 | 2019 |
Whole grain intake associated molecule 5-aminovaleric acid betaine decreases β-oxidation of fatty acids in mouse cardiomyocytes O Kärkkäinen, T Tuomainen, V Koistinen, M Tuomainen, J Leppänen, ... Scientific reports 8 (1), 13036, 2018 | 15 | 2018 |
HX600, a synthetic agonist for RXR-Nurr1 heterodimer complex, prevents ischemia-induced neuronal damage S Loppi, N Kolosowska, O Kärkkäinen, P Korhonen, M Huuskonen, ... Brain, behavior, and immunity 73, 670-681, 2018 | 14 | 2018 |
Increased metabotropic glutamate 2/3 receptor binding in the perigenual anterior cingulate cortex of Cloninger type 2 alcoholics: a whole-hemisphere autoradiography study V Laukkanen, O Kärkkäinen, J Kupila, H Kautiainen, J Tiihonen, M Storvik Alcohol and Alcoholism 50 (1), 62-67, 2015 | 13 | 2015 |
“Notame”: Workflow for Non-Targeted LC–MS Metabolic Profiling A Klåvus, M Kokla, S Noerman, VM Koistinen, M Tuomainen, I Zarei, ... Metabolites 10 (4), 135, 2020 | 12 | 2020 |
Metabolic Profiling of High Egg Consumption and the Associated Lower Risk of Type 2 Diabetes in Middle‐Aged Finnish Men S Noerman, O Kärkkäinen, A Mattsson, J Paananen, M Lehtonen, T Nurmi, ... Molecular nutrition & food research 63 (5), 1800605, 2019 | 12 | 2019 |
Quantitative assessment of betainized compounds and associations with dietary and metabolic biomarkers in the randomized study of the healthy Nordic diet (SYSDIET) M Tuomainen, O Kärkkäinen, J Leppänen, S Auriola, M Lehtonen, ... The American journal of clinical nutrition 110 (5), 1108-1118, 2019 | 10 | 2019 |
Decreased serum total cholesterol is associated with a history of childhood physical violence in depressed outpatients SL Kraav, T Tolmunen, O Kärkkäinen, A Ruusunen, H Viinamäki, ... Psychiatry research 272, 326-333, 2019 | 10 | 2019 |
[3H] Ifenprodil binding in post-mortem brains of Cloninger type 1 and 2 alcoholics: A whole-hemisphere autoradiography study J Kupila, O Kärkkäinen, V Laukkanen, M Häkkinen, H Kautiainen, ... Psychiatry Research: Neuroimaging, 2015 | 9 | 2015 |
Changes in the serum metabolite profile correlate with decreased brain gray matter volume in moderate-to-heavy drinking young adults N Heikkinen, O Kärkkäinen, E Laukkanen, V Kekkonen, O Kaarre, ... Alcohol 75, 89-97, 2019 | 8 | 2019 |
A non-targeted LC-MS profiling reveals elevated levels of carnitine precursors and trimethylated compounds in the cord plasma of pre-eclamptic infants T Jääskeläinen, O Kärkkäinen, J Jokkala, K Litonius, S Heinonen, ... Scientific reports 8 (1), 1-12, 2018 | 8 | 2018 |
Decreased [³H] naloxone Binding in the Dentate Gyrus of Cloninger Type 1 Anxiety‐Prone Alcoholics: A Postmortem Whole‐Hemisphere Autoradiography Study V Laukkanen, O Kärkkäinen, H Kautiainen, J Tiihonen, M Storvik Alcoholism: Clinical and Experimental Research 39 (8), 1352-1359, 2015 | 8 | 2015 |
Lower [3H] Citalopram Binding in Brain Areas Related to Social Cognition in Alcoholics O Kärkkäinen, V Laukkanen, T Haukijärvi, H Kautiainen, J Tiihonen, ... Alcohol and Alcoholism 50 (1), 46-50, 2015 | 7 | 2015 |
Endogenous cannabinoids in amygdala and hippocampus in post-mortem brains of Cloninger type 1 and 2 alcoholics OK Kärkkäinen, M Lehtonen, V Laukkanen, E Tupala, P Hyytiä, ... Alcohol 47 (5), 399-403, 2013 | 7 | 2013 |
Changes in the human metabolome associated with alcohol use: a review T Voutilainen, O Kärkkäinen Alcohol and Alcoholism 54 (3), 225-234, 2019 | 6 | 2019 |