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Renae M Ryan
Renae M Ryan
The University of Sydney, Australia
Verified email at sydney.edu.au
Title
Cited by
Cited by
Year
Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter
O Boudker, RM Ryan, D Yernool, K Shimamoto, E Gouaux
Nature 445 (7126), 387-393, 2007
5462007
Mechanisms of glutamate transport
RJ Vandenberg, RM Ryan
Physiological reviews 93 (4), 1621-1657, 2013
3712013
Targeting glutamine transport to suppress melanoma cell growth
Q Wang, KA Beaumont, NJ Otte, J Font, CG Bailey, M van Geldermalsen, ...
International journal of cancer 135 (5), 1060-1071, 2014
2352014
The chloride permeation pathway of a glutamate transporter and its proximity to the glutamate translocation pathway
RM Ryan, AD Mitrovic, RJ Vandenberg
Journal of Biological Chemistry 279 (20), 20742-20751, 2004
1372004
Loss-of-function mutations in the glutamate transporter SLC1A1 cause human dicarboxylic aminoaciduria
CG Bailey, RM Ryan, AD Thoeng, C Ng, K King, JM Vanslambrouck, ...
The Journal of clinical investigation 121 (1), 446-453, 2011
1322011
The uncoupled chloride conductance of a bacterial glutamate transporter homolog
RM Ryan, JA Mindell
Nature structural & molecular biology 14 (5), 365-371, 2007
1262007
Functional characterization of a Na+-dependent aspartate transporter from Pyrococcus horikoshii
RM Ryan, ELR Compton, JA Mindell
Journal of biological chemistry 284 (26), 17540-17548, 2009
1192009
Glycine transport inhibitors for the treatment of pain
RJ Vandenberg, RM Ryan, JE Carland, WL Imlach, MJ Christie
Trends in pharmacological sciences 35 (8), 423-430, 2014
862014
Position of the Third Na+ Site in the Aspartate Transporter GltPh and the Human Glutamate Transporter, EAAT1
T Bastug, G Heinzelmann, S Kuyucak, M Salim, RJ Vandenberg, ...
PloS one 7 (3), e33058, 2012
842012
Distinct conformational states mediate the transport and anion channel properties of the glutamate transporter EAAT-1
RM Ryan, RJ Vandenberg
Journal of Biological Chemistry 277 (16), 13494-13500, 2002
812002
Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5
AJ Scopelliti, J Font, RJ Vandenberg, O Boudker, RM Ryan
Nature Communications 9 (1), 38, 2018
782018
Effects of sumatriptan on rat medullary dorsal horn neurons
EA Jennings, RM Ryan, MJ Christie
Pain 111 (1), 30-37, 2004
522004
Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways
M van Geldermalsen, LE Quek, N Turner, N Freidman, A Pang, YF Guan, ...
BMC cancer 18, 1-14, 2018
512018
Glutamate transporters have a chloride channel with two hydrophobic gates
I Chen, S Pant, Q Wu, RJ Cater, M Sobti, RJ Vandenberg, AG Stewart, ...
Nature 591 (7849), 327-331, 2021
492021
Amino acid transporters and exchangers from the SLC1A family: structure, mechanism and roles in physiology and cancer
N Freidman, I Chen, Q Wu, C Briot, J Holst, J Font, R Vandenberg, R Ryan
Neurochemical Research 45, 1268-1286, 2020
472020
The domain interface of the human glutamate transporter EAAT1 mediates chloride permeation
RJ Cater, RJ Vandenberg, RM Ryan
Biophysical journal 107 (3), 621-629, 2014
472014
Structural optimization and pharmacological evaluation of inhibitors targeting dual-specificity tyrosine phosphorylation-regulated kinases (DYRK) and CDC-like kinases (CLK) in …
Q Zhou, AF Phoa, RH Abbassi, M Hoque, TA Reekie, JS Font, RM Ryan, ...
Journal of Medicinal Chemistry 60 (5), 2052-2070, 2017
462017
Monoterpene Glycoside ESK246 from Pittosporum Targets LAT3 Amino Acid Transport and Prostate Cancer Cell Growth
Q Wang, T Grkovic, J Font, S Bonham, RH Pouwer, CG Bailey, AM Moran, ...
ACS Chemical Biology 9 (6), 1369-1376, 2014
452014
Slips, leaks and channels in glutamate transporters
R Vandenberg, S Huang, R Ryan
Channels 2 (1), 51-58, 2008
422008
Molecular determinants for functional differences between alanine-serine-cysteine transporter 1 and other glutamate transporter family members
AJ Scopelliti, RM Ryan, RJ Vandenberg
Journal of Biological Chemistry 288 (12), 8250-8257, 2013
402013
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