Structure and mechanism of the M2 proton channel of influenza A virus JR Schnell, JJ Chou Nature 451 (7178), 591-595, 2008 | 1292 | 2008 |
Structure, dynamics, and catalytic function of dihydrofolate reductase JR Schnell, HJ Dyson, PE Wright Annu. Rev. Biophys. Biomol. Struct. 33, 119-140, 2004 | 647 | 2004 |
Regulation of T cell receptor activation by dynamic membrane binding of the CD3ɛ cytoplasmic tyrosine-based motif C Xu, E Gagnon, ME Call, JR Schnell, CD Schwieters, CV Carman, ... Cell 135 (4), 702-713, 2008 | 514 | 2008 |
Mechanism of drug inhibition and drug resistance of influenza A M2 channel RM Pielak, JR Schnell, JJ Chou Proceedings of the National Academy of Sciences 106 (18), 7379-7384, 2009 | 413 | 2009 |
Backbone dynamics in dihydrofolate reductase complexes: role of loop flexibility in the catalytic mechanism MJ Osborne, J Schnell, SJ Benkovic, HJ Dyson, PE Wright Biochemistry 40 (33), 9846-9859, 2001 | 315 | 2001 |
The structure of the ζζ transmembrane dimer reveals features essential for its assembly with the T cell receptor ME Call, JR Schnell, C Xu, RA Lutz, JJ Chou, KW Wucherpfennig Cell 127 (2), 355-368, 2006 | 263 | 2006 |
Defining the role of active-site loop fluctuations in dihydrofolate reductase catalysis D McElheny, JR Schnell, JC Lansing, HJ Dyson, PE Wright Proceedings of the National Academy of Sciences 102 (14), 5032-5037, 2005 | 206 | 2005 |
Perturbations of native membrane protein structure in alkyl phosphocholine detergents: a critical assessment of NMR and biophysical studies C Chipot, F Dehez, JR Schnell, N Zitzmann, E Pebay-Peyroula, LJ Catoire, ... Chemical reviews 118 (7), 3559-3607, 2018 | 167 | 2018 |
Structural model for the protein-translocating element of the twin-arginine transport system F Rodriguez, SL Rouse, CE Tait, J Harmer, A De Riso, CR Timmel, ... Proceedings of the National Academy of Sciences 110 (12), E1092-E1101, 2013 | 135 | 2013 |
Structure of a central component of the yeast kinetochore: the Spc24p/Spc25p globular domain RR Wei, JR Schnell, NA Larsen, PK Sorger, JJ Chou, SC Harrison Structure 14 (6), 1003-1009, 2006 | 126 | 2006 |
Effect of cofactor binding and loop conformation on side chain methyl dynamics in dihydrofolate reductase JR Schnell, HJ Dyson, PE Wright Biochemistry 43 (2), 374-383, 2004 | 95 | 2004 |
Amantadine partition and localization in phospholipid membrane: a solution NMR study J Wang, JR Schnell, JJ Chou Biochemical and biophysical research communications 324 (1), 212-217, 2004 | 93 | 2004 |
A distal mutation perturbs dynamic amino acid networks in dihydrofolate reductase DD Boehr, JR Schnell, D McElheny, SH Bae, BM Duggan, SJ Benkovic, ... Biochemistry 52 (27), 4605-4619, 2013 | 92 | 2013 |
Characterization of the human sigma-1 receptor chaperone domain structure and binding immunoglobulin protein (BiP) interactions JL Ortega-Roldan, F Ossa, JR Schnell Journal of Biological Chemistry 288 (29), 21448-21457, 2013 | 90 | 2013 |
Rapid and accurate structure determination of coiled‐coil domains using NMR dipolar couplings: Application to cGMP‐dependent protein kinase Iα JR Schnell, GP Zhou, M Zweckstetter, AC Rigby, JJ Chou Protein science 14 (9), 2421-2428, 2005 | 68 | 2005 |
A conserved amphipathic helix is required for membrane tubule formation by Yop1p JP Brady, JK Claridge, PG Smith, JR Schnell Proceedings of the National Academy of Sciences 112 (7), E639-E648, 2015 | 66 | 2015 |
Binding-Induced Activation of DNA Alkylation by Duocarmycin SA: Insights from the Structure of an Indole Derivative− DNA Adduct JR Schnell, RR Ketchem, DL Boger, WJ Chazin Journal of the American Chemical Society 121 (24), 5645-5652, 1999 | 61 | 1999 |
A C-terminal amphipathic helix is necessary for the in vivo tubule-shaping function of a plant reticulon E Breeze, N Dzimitrowicz, V Kriechbaumer, R Brooks, SW Botchway, ... Proceedings of the National Academy of Sciences 113 (39), 10902-10907, 2016 | 59 | 2016 |
Allosteric activation of an ion channel triggered by modification of mechanosensitive nano-pockets C Kapsalis, B Wang, H El Mkami, SJ Pitt, JR Schnell, TK Smith, JD Lippiat, ... Nature Communications 10 (1), 4619, 2019 | 54 | 2019 |
Solution NMR studies reveal the location of the second transmembrane domain of the human sigma-1 receptor JL Ortega-Roldan, F Ossa, NT Amin, JR Schnell FEBS letters 589 (5), 659-665, 2015 | 46 | 2015 |