| Enrichment-triggered prodrug activation demonstrated through mitochondria-targeted delivery of doxorubicin and carbon monoxide Y Zheng, X Ji, B Yu, K Ji, D Gallo, E Csizmadia, M Zhu, MR Choudhury, ... Nature chemistry 10 (7), 787-794, 2018 | 235 | 2018 |
| Click and release: bioorthogonal approaches to “on-demand” activation of prodrugs X Ji, Z Pan, B Yu, LK De La Cruz, Y Zheng, B Ke, B Wang Chemical Society Reviews 48 (4), 1077-1094, 2019 | 231 | 2019 |
| Toward hydrogen sulfide based therapeutics: critical drug delivery and developability issues Y Zheng, B Yu, LK De La Cruz, M Roy Choudhury, A Anifowose, B Wang Medicinal Research Reviews 38 (1), 57-100, 2018 | 166 | 2018 |
| Strategies to target the Hedgehog signaling pathway for cancer therapy M Xin, X Ji, LK De La Cruz, S Thareja, B Wang Medicinal Research Reviews 38 (3), 870-913, 2018 | 101 | 2018 |
| Toward direct protein S-persulfidation: a prodrug approach that directly delivers hydrogen persulfide B Yu, Y Zheng, Z Yuan, S Li, H Zhu, LK De La Cruz, J Zhang, K Ji, S Wang, ... Journal of the American Chemical Society 140 (1), 30-33, 2018 | 77 | 2018 |
| pH-Sensitive metal-free carbon monoxide prodrugs with tunable and predictable release rates X Ji, LKC De La Cruz, Z Pan, V Chittavong, B Wang Chemical communications 53 (69), 9628-9631, 2017 | 71 | 2017 |
| Esterase-sensitive and pH-controlled carbon monoxide prodrugs for treating systemic inflammation X Ji, Z Pan, C Li, T Kang, LKC De La Cruz, L Yang, Z Yuan, B Ke, B Wang Journal of Medicinal Chemistry 62 (6), 3163-3168, 2019 | 61 | 2019 |
| Click, release, and fluoresce: a chemical strategy for a cascade prodrug system for codelivery of carbon monoxide, a drug payload, and a fluorescent reporter LKC De La Cruz, SL Benoit, Z Pan, B Yu, RJ Maier, X Ji, B Wang Organic letters 20 (4), 897-900, 2018 | 53 | 2018 |
| Role of carbon monoxide in host–gut microbiome communication CP Hopper, LK De La Cruz, KV Lyles, LK Wareham, JA Gilbert, ... Chemical Reviews 120 (24), 13273-13311, 2020 | 50 | 2020 |
| Nitro reduction-based fluorescent probes for carbon monoxide require reactivity involving a ruthenium carbonyl moiety Z Yuan, X Yang, LK De La Cruz, B Wang Chemical communications 56 (14), 2190-2193, 2020 | 49 | 2020 |
| Click and release: a high-content bioorthogonal prodrug with multiple outputs X Ji, RE Aghoghovbia, LKC De La Cruz, Z Pan, X Yang, B Yu, B Wang Organic letters 21 (10), 3649-3652, 2019 | 34 | 2019 |
| Towards “CO in a pill”: Pharmacokinetic studies of carbon monoxide prodrugs in mice M Wang, X Yang, Z Pan, Y Wang, LK De La Cruz, B Wang, C Tan Journal of controlled release 327, 174-185, 2020 | 30 | 2020 |
| Adapting decarbonylation chemistry for the development of prodrugs capable of in vivo delivery of carbon monoxide utilizing sweeteners as carrier molecules LK De La Cruz, X Yang, A Menshikh, M Brewer, W Lu, M Wang, S Wang, ... Chemical Science 12 (31), 10649-10654, 2021 | 28 | 2021 |
| Carbon monoxide signaling: Examining its engagement with various molecular targets in the context of binding affinity, concentration, and biologic response Z Yuan, LK De La Cruz, X Yang, B Wang Pharmacological Reviews 74 (3), 825-875, 2022 | 17 | 2022 |
| Upregulation of p53 through induction of MDM2 degradation: Anthraquinone analogs AB Draganov, X Yang, A Anifowose, LKC De La Cruz, C Dai, N Ni, ... Bioorganic & medicinal chemistry 27 (17), 3860-3865, 2019 | 16 | 2019 |
| Activated charcoal dispersion of carbon monoxide prodrugs for oral delivery of CO in a pill X Yang, W Lu, M Wang, LK De La Cruz, C Tan, B Wang International journal of pharmaceutics 618, 121650, 2022 | 7 | 2022 |
| Light-activated CO donor as a universal CO surrogate for Pd-catalyzed and light-mediated carbonylation LK De La Cruz, N Bauer, A Cachuela, WS Tam, R Tripathi, X Yang, ... Organic letters 24 (27), 4902-4907, 2022 | 6 | 2022 |
| Click, release, and fluoresce: in-vivo generation of CO with concomitant synthesis of a fluorescent reporter LK De La Cruz, X Ji, X Yang, B Wang Bioorganic & Medicinal Chemistry 44, 116297, 2021 | 3 | 2021 |
| Endogenous CO production in sickness and in health LK De La Cruz, B Wang Carbon Monoxide in Drug Discovery: Basics, Pharmacology, and Therapeutic …, 2022 | 1 | 2022 |
| Caging Carbon Monoxide For Therapeutic Applications And Carbonylation Reactions LKC De La Cruz | | 2020 |
