Optimization of the allylic oxidation in the synthesis of 7-keto-Δ5-steroidal substrates ES Arsenou, AI Koutsourea, MA Fousteris, SS Nikolaropoulos Steroids 68 (5), 407-414, 2003 | 69 | 2003 |
Improved chromium-catalyzed allylic oxidation of Δ5-steroids with t-butyl hydroperoxide MA Fousteris, AI Koutsourea, SS Nikolaropoulos, A Riahi, J Muzart Journal of Molecular Catalysis A: Chemical 250 (1-2), 70-74, 2006 | 60 | 2006 |
Pyrrolo[2,3-a]carbazoles as Potential Cyclin Dependent Kinase 1 (CDK1) Inhibitors. Synthesis, Biological Evaluation, and Binding Mode through Docking Simulations MA Fousteris, A Papakyriakou, A Koutsourea, M Manioudaki, ... Journal of medicinal chemistry 51 (4), 1048-1052, 2008 | 51 | 2008 |
Rational design, synthesis, and in vivo evaluation of the antileukemic activity of six new alkylating steroidal esters AI Koutsourea, MA Fousteris, ES Arsenou, A Papageorgiou, GN Pairas, ... Bioorganic & medicinal chemistry 16 (9), 5207-5215, 2008 | 45 | 2008 |
Synthetic approaches for the synthesis of a cytostatic steroidal B–D bilactam AI Koutsourea, ES Arsenou, MA Fousteris, SS Nikolaropoulos Steroids 68 (7-8), 659-666, 2003 | 39 | 2003 |
The allylic 7-ketone at the steroidal skeleton is crucial for the antileukemic potency of chlorambucil's active metabolite steroidal esters ES Arsenou, MA Fousteris, AI Koutsourea, A Papageorgiou, V Karayianni, ... Anti-cancer drugs 15 (10), 983-990, 2004 | 33 | 2004 |
Synthesis and cytotoxic activity of new artemisinin hybrid molecules against human leukemia cells AS Letis, EJ Seo, SS Nikolaropoulos, T Efferth, A Giannis, MA Fousteris Bioorganic & Medicinal Chemistry 25 (13), 3357-3367, 2017 | 32 | 2017 |
20-Aminosteroids as a novel class of selective and complete androgen receptor antagonists and inhibitors of prostate cancer cell growth MA Fousteris, U Schubert, D Roell, J Roediger, N Bailis, ... Bioorganic & medicinal chemistry 18 (19), 6960-6969, 2010 | 31 | 2010 |
Genotoxic, cytostatic, antineoplastic and apoptotic effects of newly synthesized antitumour steroidal esters I Karapidaki, A Bakopoulou, A Papageorgiou, Z Iakovidou, E Mioglou, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 675 (1-2 …, 2009 | 28 | 2009 |
Steroidal isoxazoles, isoxazolines and isoxazolidines C Camoutsis, S Nikolaropoulos Journal of heterocyclic chemistry 35 (4), 731-759, 1998 | 28 | 1998 |
7-Keto hybrid steroidal esters of nitrogen mustard: cytogenetic and antineoplastic effects V Karayianni, A Papageorgiou, E Mioglou, Z Iakovidou, D Mourelatos, ... Anti-cancer drugs 13 (6), 637-643, 2002 | 27 | 2002 |
Aneugenic potential of the nitrogen mustard analogues melphalan, chlorambucil and pN, N-bis (2-chloroethyl) aminophenylacetic acid in cell cultures in vitro M Efthimiou, C Andrianopoulos, G Stephanou, NA Demopoulos, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 617 (1 …, 2007 | 26 | 2007 |
Structure–anti-leukemic activity relationship study of B-and D-ring modified and non-modified steroidal esters of chlorambucil's active metabolite A Papageorgiou, AI Koutsourea, ES Arsenou, MA Fousteris, D Mourelatos, ... Anti-cancer drugs 16 (10), 1075-1082, 2005 | 25 | 2005 |
7-keto-delta (5)-steroids: key-molecules owning particular biological and chemical interest. ES Arsenou, MA Fousteris, AI Koutsourea, SS Nikolaropoulos Mini reviews in medicinal chemistry 3 (6), 557-567, 2003 | 24 | 2003 |
Cyclin-dependent kinase 5 mediates pleiotrophin-induced endothelial cell migration E Lampropoulou, I Logoviti, M Koutsioumpa, M Hatziapostolou, ... Scientific Reports 8 (1), 5893, 2018 | 21 | 2018 |
3D-Quantitative structure–activity relationships of synthetic antileishmanial ring-substituted ether phospholipids A Kapou, NP Benetis, N Avlonitis, T Calogeropoulou, M Koufaki, ... Bioorganic & medicinal chemistry 15 (3), 1252-1265, 2007 | 21 | 2007 |
A new approach for evaluating in vivo anti-leukemic activity using the SCE assay: An application on three newly synthesised anti-tumour steroidal esters V Karayianni, E Mioglou, Z Iakovidou, D Mourelatos, M Fousteris, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 535 (1 …, 2003 | 21 | 2003 |
Tricyclic indole and dihydroindole derivatives as new inhibitors of soluble guanylate cyclase K Spyridonidou, M Fousteris, M Antonia, A Chatzianastasiou, ... Bioorganic & medicinal chemistry letters 19 (16), 4810-4813, 2009 | 18 | 2009 |
Structure–anti-leukemic activity relationship study of B-and D-ring modified and non-modified steroidal esters of chlorambucil MA Fousteris, AI Koutsourea, ES Arsenou, A Papageorgiou, D Mourelatos, ... Anti-cancer drugs 17 (5), 511-519, 2006 | 18 | 2006 |
Antileukemic and cytogenetic effects of modified and non-modified esteric steroidal derivatives of 4-methyl-3-bis (2-chloroethyl) amino benzoic acid (4-Me-CABA). MA Fousteris, AI Koutsourea, ES Arsenou, A Papageorgiou, D Mourelato, ... Anticancer research 22 (4), 2293-2299, 2002 | 17 | 2002 |