| Attenuation of c GAS‐STING signaling is mediated by a p62/SQSTM 1‐dependent autophagy pathway activated by TBK1 T Prabakaran, C Bodda, C Krapp, B Zhang, MH Christensen, C Sun, ... The EMBO journal 37 (8), e97858, 2018 | 337 | 2018 |
| Lentivirus pre-packed with Cas9 protein for safer gene editing PSNM JG Choi, Y Dang, S Abraham, H Ma, J Zhang, H Guo, Y Cai, JG Mikkelsen, H Wu Gene Therapy 10 (1038), 2016 | 192* | 2016 |
| Inborn errors in RNA polymerase III underlie severe varicella zoster virus infections B Ogunjimi, SY Zhang, KB Sørensen, KA Skipper, M Carter-Timofte, ... The Journal of clinical investigation 127 (9), 3543-3556, 2017 | 128 | 2017 |
| Lentiviral delivery of co-packaged Cas9 mRNA and a Vegfa-targeting guide RNA prevents wet age-related macular degeneration in mice S Ling, S Yang, X Hu, D Yin, Y Dai, X Qian, D Wang, X Pan, J Hong, ... Nature Biomedical Engineering, 1-13, 2021 | 110 | 2021 |
| Targeted genome editing by lentiviral protein transduction of zinc-finger and TAL-effector nucleases Y Cai, RO Bak, JG Mikkelsen Elife 3, e01911, 2014 | 110 | 2014 |
| Targeting herpes simplex virus with CRISPR–Cas9 cures herpetic stromal keratitis in mice D Yin, S Ling, D Wang, Y Dai, H Jiang, X Zhou, SR Paludan, J Hong, ... Nature Biotechnology, 1-11, 2021 | 97 | 2021 |
| STEEP mediates STING ER exit and activation of signaling B Zhang, R Nandakumar, LS Reinert, J Huang, A Laustsen, Z Gao, C Sun, ... Nature immunology 21 (8), 868-879, 2020 | 88 | 2020 |
| In vivo knockout of the Vegfa gene by lentiviral delivery of CRISPR/Cas9 in mouse retinal pigment epithelium cells A Holmgaard, AL Askou, JNE Benckendorff, EA Thomsen, Y Cai, T Bek, ... Molecular Therapy-Nucleic Acids 9, 89-99, 2017 | 72 | 2017 |
| Efficient sleeping beauty DNA transposition from DNA minicircles N Sharma, Y Cai, RO Bak, MR Jakobsen, LD Schrøder, JG Mikkelsen Molecular Therapy-Nucleic Acids 2, 2013 | 48 | 2013 |
| An overview of development in gene therapeutics in China D Wang, K Wang, Y Cai Gene Therapy 27 (7), 338-348, 2020 | 38 | 2020 |
| DNA transposition by protein transduction of the piggyBac transposase from lentiviral Gag precursors Y Cai, RO Bak, LB Krogh, NH Staunstrup, B Moldt, TJ Corydon, ... Nucleic Acids Research 42 (4), e28-e28, 2014 | 35 | 2014 |
| Induction of cytogenetic adaptive response in spermatogonia and spermatocytes by pre-exposure of mouse testis to low-dose 12C6+ ions H Zhang, W Zhao, Y Wang, N Li, Z Wu, Y Liu, J Chen, Y Cai Mutation Research/Genetic Toxicology and Environmental Mutagenesis 653 (1-2 …, 2008 | 22 | 2008 |
| DeepAntigen: a novel method for neoantigen prioritization via 3D genome and deep sparse learning Y Shi, Z Guo, X Su, L Meng, M Zhang, J Sun, C Wu, M Zheng, X Shang, ... Bioinformatics 36 (19), 4894-4901, 2020 | 21 | 2020 |
| Cellular requirements for sensing and elimination of incoming HSV-1 DNA and capsids C Sun, S Luecke, C Bodda, KL Jønsson, Y Cai, BC Zhang, SB Jensen, ... Journal of Interferon & Cytokine Research 39 (4), 191-204, 2019 | 20 | 2019 |
| Targeted, homology-driven gene insertion in stem cells by ZFN-loaded ‘all-in-one’lentiviral vectors Y Cai, A Laustsen, Y Zhou, C Sun, MV Anderson, S Li, N Uldbjerg, Y Luo, ... Elife 5, e12213, 2016 | 20 | 2016 |
| Driving DNA transposition by lentiviral protein transduction Y Cai, JG Mikkelsen Mobile Genetic Elements 4 (3), e28, 2014 | 16 | 2014 |
| Lentiviral delivery of proteins for genome engineering Y Cai, JG Mikkelsen Current Gene Therapy 16 (3), 194-206, 2016 | 15 | 2016 |
| Essential role of autophagy in restricting poliovirus infection revealed by identification of an ATG7 defect in a poliomyelitis patient NS Brinck Andersen, SE Jørgensen, KA Skipper, SM Larsen, J Heinz, ... Autophagy 17 (9), 2449-2464, 2021 | 12 | 2021 |
| A single dose SARS-CoV-2 simulating particle vaccine induces potent neutralizing activities D Yin, S Ling, X Tian, Y Li, Z Xu, H Jiang, X Zhang, X Wang, Y Shi, ... bioRxiv, 2020.05. 14.093054, 2020 | 9 | 2020 |
| In vivo CRISPR gene editing in patients with herpes stromal keratitis A Wei, D Yin, Z Zhai, S Ling, H Le, L Tian, J Xu, SR Paludan, Y Cai, ... medRxiv, 2023.02. 21.23285822, 2023 | 5 | 2023 |
Rasmus O. BakAssociate Professor, PhD, Aarhus University, Dept. of BiomedicineVahvistettu sähköpostiosoite verkkotunnuksessa biomed.au.dk
