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Kensaku Matsunami
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Decision support method for the choice between batch and continuous technologies in solid drug product manufacturing
K Matsunami, T Miyano, H Arai, H Nakagawa, M Hirao, H Sugiyama
Industrial & Engineering Chemistry Research 57 (30), 9798-9809, 2018
562018
A large-scale experimental comparison of batch and continuous technologies in pharmaceutical tablet manufacturing using ethenzamide
K Matsunami, T Nagato, K Hasegawa, H Sugiyama
International journal of pharmaceutics 559, 210-219, 2019
392019
Determining key parameters of continuous wet granulation for tablet quality and productivity: A case in ethenzamide
K Matsunami, T Nagato, K Hasegawa, H Sugiyama
International Journal of Pharmaceutics 579, 119160, 2020
252020
Superstructure-based process synthesis and economic assessment under uncertainty for solid drug product manufacturing
K Matsunami, F Sternal, K Yaginuma, S Tanabe, H Nakagawa, ...
BMC Chemical Engineering 2, 1-16, 2020
172020
Analysis of the effects of process parameters on start-up operation in continuous wet granulation
K Matsunami, A Ryckaert, M Peeters, S Badr, H Sugiyama, I Nopens, ...
Processes 9 (9), 1502, 2021
112021
Evaluation of the influence of material properties and process parameters on granule porosity in twin-screw wet granulation
M Peeters, AAB Jiménez, K Matsunami, F Stauffer, I Nopens, T De Beer
International Journal of Pharmaceutics 641, 123010, 2023
62023
Surrogate modeling of dissolution behavior toward efficient design of tablet manufacturing processes
K Matsunami, T Miura, K Yaginuma, S Tanabe, S Badr, H Sugiyama
Computers & Chemical Engineering 171, 108141, 2023
62023
Linking material properties to 1D-PBM parameters towards a generic model for twin-screw wet granulation
AAB Jiménez, K Matsunami, D Van Hauwermeiren, M Peeters, F Stauffer, ...
Chemical Engineering Research and Design 193, 713-724, 2023
52023
Process systems engineering approaches for drug product manufacturing: from tablets to injectables
H Sugiyama, K Matsunami, K Yabuta
Computer Aided Chemical Engineering 40, 2785-2790, 2017
52017
Design framework and tools for solid drug product manufacturing processes
K Matsunami, S Badr, H Sugiyama
Optimization of Pharmaceutical Processes, 393-412, 2022
42022
Exploring the effect of raw material properties on continuous twin-screw wet granulation manufacturability
M Peeters, AAB Jiménez, K Matsunami, D Van Hauwermeiren, F Stauffer, ...
International Journal of Pharmaceutics 645, 123391, 2023
32023
Partial least squares regression to calculate population balance model parameters from material properties in continuous twin-screw wet granulation
AAB Jiménez, K Matsunami, D Van Hauwermeiren, M Peeters, F Stauffer, ...
International Journal of Pharmaceutics 640, 123040, 2023
32023
Model development and calibration of two-dimensional population balance model for twin-screw wet granulation based on particle size distribution and porosity
AAB Jiménez, K Matsunami, M Ghijs, D Van Hauwermeiren, M Peeters, ...
Powder Technology 419, 118334, 2023
32023
Determination of critical decision points for COVID-19 measures in Japan
J Kim, K Matsunami, K Okamura, S Badr, H Sugiyama
Scientific Reports 11 (1), 16416, 2021
32021
T-shaped partial least squares for high-dosed new active pharmaceutical ingredients in continuous twin-screw wet granulation: Granule size prediction with limited material …
K Matsunami, J Meyer, M Rowland, N Dawson, T De Beer, ...
International Journal of Pharmaceutics 646, 123481, 2023
22023
Framework for Designing Solid Drug Product Manufacturing Processes Based on Economic and Quality Assessment
K Matsunami, S Badr, H Sugiyama
Computer Aided Chemical Engineering 49, 223-228, 2022
22022
Economic evaluation of batch and continuous manufacturing technologies for solid drug products during clinical development
K Matsunami, S Tanabe, H Nakagawa, M Hirao, H Sugiyama
Computer Aided Chemical Engineering 44, 2131-2136, 2018
22018
Analysis of the effect of formulation properties and process parameters on granule formation in twin-screw wet granulation
M Peeters, AAB Jiménez, K Matsunami, M Ghijs, E dos Santos Schultz, ...
International Journal of Pharmaceutics 650, 123671, 2024
12024
Validation of model-based design of experiments for continuous wet granulation and drying
K Matsunami, T Vandeputte, AAB Jiménez, M Peeters, M Ghijs, ...
International Journal of Pharmaceutics 646, 123493, 2023
12023
Industrial scale experiments towards the development of process evaluation models for continuous pharmaceutical tablet manufacturing
K Matsunami, T Nagato, K Hasegawa, M Hirao, H Sugiyama
Computer Aided Chemical Engineering 43, 1655-1660, 2018
12018
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Articles 1–20