A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis J Walters, C Pop, FL Scott, M Drag, P Swartz, C Mattos, GS Salvesen, ... Biochemical Journal 424 (3), 335-345, 2009 | 216 | 2009 |
Structural origins of redox potentials in Fe-S proteins: electrostatic potentials of crystal structures PD Swartz, BW Beck, T Ichiye Biophysical journal 71 (6), 2958-2969, 1996 | 91 | 1996 |
Role of loop bundle hydrogen bonds in the maturation and activity of (Pro) caspase-3 B Feeney, C Pop, P Swartz, C Mattos, AC Clark Biochemistry 45 (44), 13249-13263, 2006 | 68 | 2006 |
Mutagenicity in Salmonella of halonitromethanes: a recently recognized class of disinfection by-products in drinking water B Kundu, SD Richardson, PD Swartz, PP Matthews, AM Richard, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 562 (1-2 …, 2004 | 62 | 2004 |
Comparative mutagenicity of halomethanes and halonitromethanes in Salmonella TA100: structure–activity analysis and mutation spectra B Kundu, SD Richardson, CA Granville, DT Shaughnessy, NM Hanley, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 554 (1 …, 2004 | 61 | 2004 |
Multiple solvent crystal structures of ribonuclease A: an assessment of the method M Dechene, G Wink, M Smith, P Swartz, C Mattos Proteins: Structure, Function, and Bioinformatics 76 (4), 861-881, 2009 | 51 | 2009 |
DRoP: a water analysis program identifies Ras-GTP-specific pathway of communication between membrane-interacting regions and the active site BM Kearney, CW Johnson, DM Roberts, P Swartz, C Mattos Journal of molecular biology 426 (3), 611-629, 2014 | 46 | 2014 |
Pulsed-alkylation mass spectrometry for the study of protein folding and dynamics: development and application to the study of a folding/unfolding intermediate of bacterial … JL Apuy, ZY Park, PD Swartz, LJ Dangott, DH Russell, TO Baldwin Biochemistry 40 (50), 15153-15163, 2001 | 46 | 2001 |
Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection PSACC Joseph J. Maciag, Sarah H. Mackenzie, Matthew B. Tucker, Joshua L ... PNAS 113 (41), 2016 | 42* | 2016 |
Temperature Dependence of the Redox Potential of Rubredoxin from Pyrococcus furiosus: A Molecular Dynamics Study PD Swartz, T Ichiye Biochemistry 35 (43), 13772-13779, 1996 | 37 | 1996 |
Allosteric modulation of caspase 3 through mutagenesis J Walters, JL Schipper, P Swartz, C Mattos, AC Clark Bioscience Reports 32 (4), 401-411, 2012 | 32 | 2012 |
Protein contributions to redox potentials of homologous rubredoxins: an energy minimization study PD Swartz, T Ichiye Biophysical journal 73 (5), 2733-2741, 1997 | 29 | 1997 |
Modifying caspase-3 activity by altering allosteric networks C Cade, P Swartz, SH MacKenzie, AC Clark Biochemistry 53 (48), 7582-7595, 2014 | 26 | 2014 |
Modifications to a common phosphorylation network provide individualized control in caspases ME Thomas, R Grinshpon, P Swartz, AC Clark Journal of Biological Chemistry 293 (15), 5447-5461, 2018 | 25 | 2018 |
Crystallization of a fungal lytic polysaccharide monooxygenase expressed from glycoengineered Pichia pastoris for X-ray and neutron diffraction WB O'Dell, PD Swartz, KL Weiss, F Meilleur Acta Crystallographica Section F: Structural Biology Communications 73 (2 …, 2017 | 24 | 2017 |
Resurrection of ancestral effector caspases identifies novel networks for evolution of substrate specificity RD Grinshpon, S Shrestha, J Titus-McQuillan, PT Hamilton, PD Swartz, ... Biochemical Journal 476 (22), 3475-3492, 2019 | 20 | 2019 |
Lengthening the intersubunit linker of procaspase 3 leads to constitutive activation SH MacKenzie, JL Schipper, EJ England, ME Thomas III, K Blackburn, ... Biochemistry 52 (36), 6219-6231, 2013 | 18 | 2013 |
Phage display and structural studies reveal plasticity in substrate specificity of caspase‐3a from zebrafish MB Tucker, SH MacKenzie, JJ Maciag, H Dirscherl Ackerman, P Swartz, ... Protein Science 25 (11), 2076-2088, 2016 | 16 | 2016 |
Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro) caspase-3 J Walters, P Swartz, C Mattos, AC Clark Archives of biochemistry and biophysics 508 (1), 31-38, 2011 | 16 | 2011 |
The role of T56 in controlling the flexibility of the distal histidine in dehaloperoxidase-hemoglobin from Amphitrite ornata S Jiang, I Wright, P Swartz, S Franzen Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (10), 2020-2029, 2013 | 14 | 2013 |