| The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer E Kansanen, SM Kuosmanen, H Leinonen, AL Levonen Redox biology 1 (1), 45-49, 2013 | 1371 | 2013 |
| Activation of stress signaling pathways by electrophilic oxidized and nitrated lipids E Kansanen, HK Jyrkkänen, AL Levonen Free Radical Biology and Medicine 52 (6), 973-982, 2012 | 255 | 2012 |
| Redox regulation of antioxidants, autophagy, and the response to stress: implications for electrophile therapeutics AL Levonen, BG Hill, E Kansanen, J Zhang, VM Darley-Usmar Free Radical Biology and Medicine 71, 196-207, 2014 | 253 | 2014 |
| Nrf2 gene transfer induces antioxidant enzymes and suppresses smooth muscle cell growth in vitro and reduces oxidative stress in rabbit aorta in vivo AL Levonen, M Inkala, T Heikura, S Jauhiainen, HK Jyrkkänen, ... Arteriosclerosis, thrombosis, and vascular biology 27 (4), 741-747, 2007 | 225 | 2007 |
| Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism E Kansanen, G Bonacci, FJ Schopfer, SM Kuosmanen, KI Tong, ... Journal of Biological Chemistry 286 (16), 14019-14027, 2011 | 221 | 2011 |
| Role of the Keap1–Nrf2 pathway in cancer HM Leinonen, E Kansanen, P Pölönen, M Heinäniemi, AL Levonen Advances in cancer research 122, 281-320, 2014 | 186 | 2014 |
| Nrf2-dependent and-independent responses to nitro-fatty acids in human endothelial cells E Kansanen, HK Jyrkkänen, OL Volger, H Leinonen, AM Kivelä, ... Journal of Biological Chemistry 284 (48), 33233-33241, 2009 | 185 | 2009 |
| Nrf2 regulates antioxidant gene expression evoked by oxidized phospholipids in endothelial cells and murine arteries in vivo HK Jyrkkänen, E Kansanen, M Inkala, AM Kivelä, H Hurttila, ... Circulation research 103 (1), e1-e9, 2008 | 171 | 2008 |
| Regulation of Nrf2-dependent gene expression by 15-deoxy-Δ12, 14-prostaglandin J2 E Kansanen, AM Kivelä, AL Levonen Free Radical Biology and Medicine 47 (9), 1310-1317, 2009 | 157 | 2009 |
| Enhanced polyamine catabolism alters homeostatic control of white adipose tissue mass, energy expenditure, and glucose metabolism E Pirinen, T Kuulasmaa, M Pietilä, S Heikkinen, M Tusa, P Itkonen, ... Molecular and cellular biology 27 (13), 4953-4967, 2007 | 151 | 2007 |
| Simvastatin has an anti-inflammatory effect on macrophages via upregulation of an atheroprotective transcription factor, Kruppel-like factor 2 TT Tuomisto, H Lumivuori, E Kansanen, SK Häkkinen, MP Turunen, ... Cardiovascular research 78 (1), 175-184, 2008 | 146 | 2008 |
| The absence of macrophage Nrf2 promotes early atherogenesis AK Ruotsalainen, M Inkala, ME Partanen, JP Lappalainen, E Kansanen, ... Cardiovascular research 98 (1), 107-115, 2013 | 104 | 2013 |
| Novel insights into the regulation of antioxidant-response-elementmediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2 HK Jyrkkänen, S Kuosmanen, M Heinäniemi, H Laitinen, E Kansanen, ... Biochemical Journal 440 (2), 167-174, 2011 | 92 | 2011 |
| Dysregulation of the Keap1–Nrf2 pathway in cancer HM Leinonen, E Kansanen, P Pölönen, M Heinäniemi, AL Levonen Biochemical Society Transactions 43 (4), 645-649, 2015 | 83 | 2015 |
| Oxidative stress-inducible lentiviral vectors for gene therapy H Hurttila, JK Koponen, E Kansanen, HK Jyrkkänen, A Kivelä, R Kylätie, ... Gene therapy 15 (18), 1271-1279, 2008 | 66 | 2008 |
| NRF2 regulates endothelial glycolysis and proliferation with miR-93 and mediates the effects of oxidized phospholipids on endothelial activation SM Kuosmanen, E Kansanen, MU Kaikkonen, V Sihvola, K Pulkkinen, ... Nucleic Acids Research 46 (3), 1124-1138, 2018 | 62 | 2018 |
| Novel keto-phospholipids are generated by monocytes and macrophages, detected in cystic fibrosis, and activate peroxisome proliferator-activated receptor-γ VJ Hammond, AH Morgan, S Lauder, CP Thomas, S Brown, BA Freeman, ... Journal of Biological Chemistry 287 (50), 41651-41666, 2012 | 62 | 2012 |
| MicroRNA profiling reveals distinct profiles for tissue-derived and cultured endothelial cells SM Kuosmanen, E Kansanen, V Sihvola, AL Levonen Scientific reports 7 (1), 10943, 2017 | 57 | 2017 |
| Control of VEGF-A transcriptional programs by pausing and genomic compartmentalization MU Kaikkonen, H Niskanen, CE Romanoski, E Kansanen, AM Kivelä, ... Nucleic acids research 42 (20), 12570-12584, 2014 | 55 | 2014 |
| Oxidative stress-regulated lentiviral TK/GCV gene therapy for lung cancer treatment HM Leinonen, AK Ruotsalainen, AM Määttä, HM Laitinen, ... Cancer research 72 (23), 6227-6235, 2012 | 55 | 2012 |
