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Bryan Knuckley
Bryan Knuckley
Verified email at unf.edu
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Cited by
Year
Inhibitors and Inactivators of Protein Arginine Deiminase 4:  Functional and Structural Characterization,
Y Luo, K Arita, M Bhatia, B Knuckley, YH Lee, MR Stallcup, M Sato, ...
Biochemistry 45 (39), 11727-11736, 2006
3272006
N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis
VC Willis, AM Gizinski, NK Banda, CP Causey, B Knuckley, KN Cordova, ...
The Journal of Immunology 186 (7), 4396-4404, 2011
3232011
Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential
J Jones, C Causey, B Knuckley, JL Slack-Noyes, PR Thompson
Current opinion in drug discovery & development 12 (5), 616, 2009
2692009
Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor
AA Chumanevich, CP Causey, BA Knuckley, JE Jones, D Poudyal, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 300 (6 …, 2011
2172011
Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3
B Knuckley, CP Causey, JE Jones, M Bhatia, CJ Dreyton, TC Osborne, ...
Biochemistry 49 (23), 4852-4863, 2010
1892010
A fluoroacetamidine-based inactivator of protein arginine deiminase 4: design, synthesis, and in vitro and in vivo evaluation
Y Luo, B Knuckley, YH Lee, MR Stallcup, PR Thompson
Journal of the American Chemical Society 128 (4), 1092-1093, 2006
1722006
Felty's syndrome autoantibodies bind to deiminated histones and neutrophil extracellular chromatin traps
N Dwivedi, J Upadhyay, I Neeli, S Khan, D Pattanaik, L Myers, KA Kirou, ...
Arthritis & rheumatism 64 (4), 982-992, 2012
1562012
Protein arginine deiminase 4: evidence for a reverse protonation mechanism
B Knuckley, M Bhatia, PR Thompson
Biochemistry 46 (22), 6578-6587, 2007
1132007
Profiling Protein Arginine Deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors
B Knuckley, Y Luo, PR Thompson
Bioorganic & medicinal chemistry 16 (2), 739-745, 2008
1062008
A fluopol-ABPP HTS assay to identify PAD inhibitors
B Knuckley, JE Jones, DA Bachovchin, J Slack, CP Causey, SJ Brown, ...
Chemical communications 46 (38), 7175-7177, 2010
1022010
The development of N-α-(2-carboxyl) benzoyl-N 5-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl) benzoyl-N 5-(2-chloro-1-iminoethyl)-l-ornithine …
CP Causey, JE Jones, JL Slack, D Kamei, LE Jones Jr, V Subramanian, ...
Journal of medicinal chemistry 54 (19), 6919-6935, 2011
922011
Activity-based protein profiling reagents for protein arginine deiminase 4 (PAD4): synthesis and in vitro evaluation of a fluorescently labeled probe
Y Luo, B Knuckley, M Bhatia, PJ Pellechia, PR Thompson
Journal of the American Chemical Society 128 (45), 14468-14469, 2006
852006
Haloacetamidine‐based inactivators of protein arginine deiminase 4 (PAD4): evidence that general acid catalysis promotes efficient inactivation
B Knuckley, CP Causey, PJ Pellechia, PF Cook, PR Thompson
Chembiochem 11 (2), 161-165, 2010
662010
Post-training lesions of the medial prefrontal cortex interfere with subsequent performance of trace eyeblink conditioning
B Simon, B Knuckley, J Churchwell, DA Powell
Journal of Neuroscience 25 (46), 10740-10746, 2005
512005
Mechanistic studies of protein arginine deiminase 2: evidence for a substrate-assisted mechanism
CJ Dreyton, B Knuckley, JE Jones, DM Lewallen, PR Thompson
Biochemistry 53 (27), 4426-4433, 2014
432014
Prefrontal control of trace versus delay eyeblink conditioning: role of the unconditioned stimulus in rabbits (Oryctolagus cuniculus).
B Oswald, B Knuckley, K Mahan, C Sanders, DA Powell
Behavioral neuroscience 120 (5), 1033, 2006
422006
Two distinct cyclodipeptide synthases from a marine actinomycete catalyze biosynthesis of the same diketopiperazine natural product
ED James, B Knuckley, N Alqahtani, S Porwal, J Ban, JA Karty, ...
ACS Synthetic Biology 5 (7), 547-553, 2016
382016
Probing adenylation: using a fluorescently labelled ATP probe to directly label and immunoprecipitate VopS substrates
DM Lewallen, CJ Steckler, B Knuckley, MJ Chalmers, PR Thompson
Molecular BioSystems 8 (6), 1701-1706, 2012
372012
Characterization and inactivation of an agmatine deiminase from Helicobacter pylori
JE Jones, CP Causey, L Lovelace, B Knuckley, H Flick, L Lebioda, ...
Bioorganic chemistry 38 (2), 62-73, 2010
282010
Galantamine facilitates acquisition of a trace-conditioned eyeblink response in healthy, young rabbits
BB Simon, B Knuckley, DA Powell
Learning & Memory 11 (1), 116-122, 2004
272004
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