John Martin
John Martin
Materia Therapeutics
Vahvistettu sähköpostiosoite verkkotunnuksessa
Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner
VP Chauhan, T Stylianopoulos, JD Martin, Z Popović, O Chen, ...
Nature nanotechnology 7 (6), 383-388, 2012
Multistage nanoparticle delivery system for deep penetration into tumor tissue
C Wong, T Stylianopoulos, J Cui, J Martin, VP Chauhan, W Jiang, ...
Proceedings of the National Academy of Sciences 108 (6), 2426-2431, 2011
The role of mechanical forces in tumor growth and therapy
RK Jain, JD Martin, T Stylianopoulos
Annual review of biomedical engineering 16, 321-346, 2014
Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy
Y Huang, J Yuan, E Righi, WS Kamoun, M Ancukiewicz, J Nezivar, ...
Proceedings of the National Academy of Sciences 109 (43), 17561-17566, 2012
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels
VP Chauhan, JD Martin, H Liu, DA Lacorre, SR Jain, SV Kozin, ...
Nature communications 4, 2516, 2013
Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors
T Stylianopoulos, JD Martin, VP Chauhan, SR Jain, B Diop-Frimpong, ...
Proceedings of the National Academy of Sciences 109 (38), 15101-15108, 2012
Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges
JD Martin, H Cabral, T Stylianopoulos, RK Jain
Nature Reviews Clinical Oncology 17 (4), 251-266, 2020
Coevolution of solid stress and interstitial fluid pressure in tumors during progression: Implications for vascular collapse
T Stylianopoulos, JD Martin, M Snuderl, F Mpekris, SR Jain, RK Jain
Cancer research 73 (13), 3833-3841, 2013
Normalizing Function of Tumor Vessels: Progress, Opportunities, and Challenges
JD Martin, G Seano, RK Jain
Annual review of physiology 81, 505-534, 2019
Obesity-induced inflammation and desmoplasia promote pancreatic cancer progression and resistance to chemotherapy
J Incio, H Liu, P Suboj, SM Chin, IX Chen, M Pinter, MR Ng, HT Nia, ...
Cancer discovery 6 (8), 852-869, 2016
Solid stress and elastic energy as measures of tumour mechanopathology
HT Nia, H Liu, G Seano, M Datta, D Jones, N Rahbari, J Incio, ...
Nature Biomedical Engineering 1, 0004, 2016
Modeling the onset of symptoms of COVID-19
JR Larsen, MR Martin, JD Martin, P Kuhn, JB Hicks
Frontiers in public health 8, 551338, 2020
Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma
M Snuderl, A Batista, ND Kirkpatrick, CR de Almodovar, L Riedemann, ...
Cell 152 (5), 1065-1076, 2013
Role of vascular density and normalization in response to neoadjuvant bevacizumab and chemotherapy in breast cancer patients
SM Tolaney, Y Boucher, DG Duda, JD Martin, G Seano, M Ancukiewicz, ...
Proceedings of the National Academy of Sciences 112 (46), 14325-14330, 2015
Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases
NN Rahbari, D Kedrin, J Incio, H Liu, WW Ho, HT Nia, CM Edrich, K Jung, ...
Science Translational Medicine 8 (360), 360ra135-360ra135, 2016
Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery
M Datta, LE Via, WS Kamoun, C Liu, W Chen, G Seano, DM Weiner, ...
Proceedings of the National Academy of Sciences 112 (6), 1827-1832, 2015
Compression of Pancreatic Tumor Blood Vessels by Hyaluronan Is Caused by Solid Stress and Not Interstitial Fluid Pressure
VP Chauhan, Y Boucher, CR Ferrone, S Roberge, JD Martin, ...
Cancer Cell 26 (1), 14-15, 2014
Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy
VP Chauhan, IX Chen, R Tong, MR Ng, JD Martin, K Naxerova, MW Wu, ...
Proceedings of the National Academy of Sciences 116 (22), 10674-10680, 2019
Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity
JD Martin, D Fukumura, DG Duda, Y Boucher, RK Jain
Cold Spring Harbor Perspectives in Medicine 6 (12), a027094, 2016
TGF-β inhibition combined with cytotoxic nanomedicine normalizes triple negative breast cancer microenvironment towards anti-tumor immunity
M Panagi, C Voutouri, F Mpekris, P Papageorgis, MR Martin, JD Martin, ...
Theranostics 10 (4), 1910, 2020
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Artikkelit 1–20