| In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy CE Nelson, CH Hakim, DG Ousterout, PI Thakore, EA Moreb, RMC Rivera, ... Science 351 (6271), 403-407, 2016 | 1320 | 2016 |
| Large-scale bioprocess competitiveness: the potential of dynamic metabolic control in two-stage fermentations JM Burg, CB Cooper, Z Ye, BR Reed, EA Moreb, MD Lynch Current Opinion in Chemical Engineering 14, 121-136, 2016 | 121 | 2016 |
| Managing the SOS Response for Enhanced CRISPR-Cas-Based Recombineering in E. coli through Transient Inhibition of Host RecA Activity EA Moreb, B Hoover, A Yaseen, N Valyasevi, Z Roecker, ... ACS Synthetic Biology 6 (12), 2209-2218, 2017 | 48 | 2017 |
| Scalable, two‐stage, autoinduction of recombinant protein expression in E. coli utilizing phosphate depletion R Menacho‐Melgar, Z Ye, EA Moreb, T Yang, JP Efromson, JS Decker, ... Biotechnology and Bioengineering, 2020 | 38 | 2020 |
| Dynamic control over feedback regulatory mechanisms improves NADPH flux and xylitol biosynthesis in engineered E. coli S Li, Z Ye, EA Moreb, JN Hennigan, DB Castellanos, T Yang, MD Lynch Metabolic Engineering 64, 26-40, 2021 | 32 | 2021 |
| Genome dependent Cas9/gRNA search time underlies sequence dependent gRNA activity EA Moreb, MD Lynch Nature Communications 12 (1), 5034, 2021 | 31 | 2021 |
| Improved two‐stage protein expression and purification via autoinduction of both autolysis and auto DNA/RNA hydrolysis conferred by phage lysozyme and DNA/RNA endonuclease R Menacho‐Melgar, EA Moreb, JP Efromson, T Yang, JN Hennigan, ... Biotechnology and bioengineering 117 (9), 2852-2860, 2020 | 29 | 2020 |
| Media Robustness and Scalability of Phosphate Regulated Promoters Useful for Two-Stage Autoinduction in E. coli EA Moreb, Z Ye, JP Efromson, JN Hennigan, R Menacho-Melgar, ... ACS Synthetic Biology 9 (6), 1483-1486, 2020 | 28 | 2020 |
| Two-stage dynamic deregulation of metabolism improves process robustness & scalability in engineered E. coli. Z Ye, S Li, JN Hennigan, J Lebeau, EA Moreb, J Wolf, MD Lynch Metabolic Engineering 68, 106-118, 2021 | 18 | 2021 |
| CRISPR-Cas “non-target” sites inhibit on-target cutting rates EA Moreb, M Hutmacher, MD Lynch The CRISPR Journal 3 (6), 550-561, 2020 | 18 | 2020 |
| Escherichia coli Cas1/2 Endonuclease Complex Modifies Self-Targeting CRISPR/Cascade Spacers Reducing Silencing Guide Stability Z Ye, EA Moreb, S Li, J Lebeau, R Menacho-Melgar, M Munson, ... ACS Synthetic Biology 10 (1), 29-37, 2020 | 8 | 2020 |
| A meta-analysis of gRNA library screens enables an improved understanding of the impact of gRNA folding and structural stability on CRISPR-Cas9 activity EA Moreb, MD Lynch The CRISPR Journal 5 (1), 146-154, 2022 | 7 | 2022 |
| Dynamic control over feedback regulation identifies pyruvate-ferredoxin oxidoreductase as a central metabolic enzyme in stationary phase E. coli S Li, Z Ye, J Lebeau, EA Moreb, MD Lynch bioRxiv, 2020.07. 26.219949, 2020 | 6 | 2020 |
| Dynamic control over feedback regulation improves stationary phase fluxes in engineered E. coli. S Li, Z Ye, J Lebeau, EA Moreb, MD Lynch bioRxiv [Preprint], 2020 | 4 | 2020 |
| An analysis of gRNA sequence dependent cleavage highlights the importance of genomic context on CRISPR-Cas activity EA Moreb, MD Lynch BioRxiv, 2021.05. 06.442929, 2021 | 2 | 2021 |
| The E. coli Cas1/2 endonuclease complex reduces CRISPR/Cascade guide array stability Z Ye, J Lebeau, EA Moreb, R Menacho-Melgar, MD Lynch bioRxiv, 2020.07. 27.223214, 2020 | 1 | 2020 |
| 397. Correction of the Dystrophin Gene By the CRISPR/Cas9 System in a Mouse Model of Muscular Dystrophy CE Nelson, DG Ousterout, JN Robinson-Hamm, EA Moreb, ... Molecular Therapy 23, S157-S158, 2015 | 1 | 2015 |
| 2-Stage microfermentations S Li, Z Ye, EA Moreb, R Menacho-Melgar, M Golovsky, MD Lynch Metabolic Engineering Communications, e00233, 2024 | | 2024 |
| Compositions and methods for auto-inducible cellular lysis and nucleotide hydrolysis MD Lynch, RM Melgar, EA Moreb, JP Efromson US Patent App. 17/758,477, 2023 | | 2023 |
| Composistions and methods for crispr enabled dna synthesis MD Lynch, EA Moreb, T Yang US Patent App. 17/758,480, 2023 | | 2023 |
