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Kathleen (Kate) E. Prosser
Kathleen (Kate) E. Prosser
Natural Resources Canada
Verified email at nrcan-rncan.gc.ca
Title
Cited by
Cited by
Year
Expanding medicinal chemistry into 3D space: Metallofragments as 3D scaffolds for fragment-based drug discovery
CN Morrison, KE Prosser, RW Stokes, A Cordes, N Metzler-Nolte, ...
Chemical science 11 (5), 1216-1225, 2020
1232020
Anticancer copper pyridine benzimidazole complexes: ROS generation, biomolecule interactions, and cytotoxicity
KE Prosser, SW Chang, F Saraci, PH Le, CJ Walsby
Journal of inorganic biochemistry 167, 89-99, 2017
1072017
CF3 Derivatives of the Anticancer Ru(III) Complexes KP1019, NKP-1339, and Their Imidazole and Pyridine Analogues Show Enhanced Lipophilicity, Albumin …
SW Chang, AR Lewis, KE Prosser, JR Thompson, M Gladkikh, MB Bally, ...
Inorganic chemistry 55 (10), 4850-4863, 2016
722016
Lowering water oxidation overpotentials using the ionisable imidazole of copper (2-(2′-pyridyl) imidazole)
LA Stott, KE Prosser, EK Berdichevsky, CJ Walsby, JJ Warren
Chemical communications 53 (3), 651-654, 2017
662017
Activation by oxidation: Ferrocene-functionalized Ru (II)-arene complexes with anticancer, antibacterial, and antioxidant properties
C Mu, KE Prosser, S Harrypersad, GA MacNeil, R Panchmatia, ...
Inorganic Chemistry 57 (24), 15247-15261, 2018
602018
A catalytic antioxidant for limiting amyloid-beta peptide aggregation and reactive oxygen species generation
LMF Gomes, A Mahammed, KE Prosser, JR Smith, MA Silverman, ...
Chemical science 10 (6), 1634-1643, 2019
492019
Evaluation of 3-dimensionality in approved and experimental drug space
KE Prosser, RW Stokes, SM Cohen
ACS medicinal chemistry letters 11 (6), 1292-1298, 2020
462020
Induction of cytotoxicity in pyridine analogues of the anti-metastatic Ru (III) complex NAMI-A by ferrocene functionalization
C Mu, SW Chang, KE Prosser, AWY Leung, S Santacruz, T Jang, ...
Inorganic chemistry 55 (1), 177-190, 2016
412016
Electronic Structure Description of a Doubly Oxidized Bimetallic Cobalt Complex with Proradical Ligands
RM Clarke, K Hazin, JR Thompson, D Savard, KE Prosser, T Storr
Inorganic Chemistry 55 (2), 762-774, 2016
352016
Electron paramagnetic resonance as a tool for studying the mechanisms of paramagnetic anticancer metallodrugs
KE Prosser, CJ Walsby
European Journal of Inorganic Chemistry 2017 (12), 1573-1585, 2017
292017
Room temperature aqueous synthesis of UiO-66 derivatives via postsynthetic exchange
M Kalaj, KE Prosser, SM Cohen
Dalton Transactions 49 (26), 8841-8845, 2020
232020
Copper (II) pyridyl Aminophenolates: Hypoxia‐Selective, Nucleus‐Targeting Cytotoxins, and magnetic resonance probes
KE Prosser, D Xie, A Chu, GA MacNeil, BR Varju, RT Kadakia, EL Que, ...
Chemistry–A European Journal 27 (38), 9839-9849, 2021
112021
A stable open-shell redox active ditopic ligand
NM Bonanno, AJ Lough, KE Prosser, CJ Walsby, PK Poddutoori, ...
Dalton Transactions 45 (13), 5460-5463, 2016
112016
Electronic Structure Evaluation of an Oxidized Tris (methoxy)‐Substituted Ni Salen Complex
L Chiang, RM Clarke, K Herasymchuk, M Sutherland, KE Prosser, ...
European Journal of Inorganic Chemistry 2016 (1), 49-55, 2016
112016
19 F-Tagged metal binding pharmacophores for NMR screening of metalloenzymes
KE Prosser, AJ Kohlbrand, H Seo, M Kalaj, SM Cohen
Chemical Communications 57 (40), 4934-4937, 2021
82021
Transition Metal Ions Promote the Bioavailability of Hydrophobic Therapeutics: Cu and Zn Interactions with RNA Polymerase I Inhibitor CX5461
KE Prosser, AWY Leung, S Harrypersad, AR Lewis, MB Bally, CJ Walsby
Chemistry–A European Journal 24 (24), 6334-6338, 2018
72018
A novel formulation of CX-5461, a small-molecule inhibitor of rRNA synthesis, and its use for treatment of acute myeloid leukemia models
AWY Leung, M Anantha, KE Prosser, M Wehbe, CJ Walsby, MB Bally
Cancer Research 76 (14_Supplement), 1319-1319, 2016
62016
Combining a Ru (II)-arene complex with a NO-releasing nitrate-ester ligand generates cytotoxic activity
J Zhao, KE Prosser, SW Chang, SP Zakharia, CJ Walsby
Dalton Transactions 45 (45), 18079-18083, 2016
62016
Metal complexed therapeutic agents and lipid-based nanoparticulate formulations thereof
M Bally, A Leung, K Prosser, C Walsby, M Wehbe, M Anantha
US Patent App. 16/061,248, 2018
42018
Optimal electrostatic interactions between substrate and protein are essential for radical chemistry in ornithine 4, 5-aminomutase
C Makins, DA Whitelaw, M McGregor, A Petit, RG Mothersole, KE Prosser, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1865 (8), 1077-1084, 2017
42017
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