| Genetic mechanisms of critical illness in COVID-19 E Pairo-Castineira, S Clohisey, L Klaric, AD Bretherick, K Rawlik, D Pasko, ... Nature 591 (7848), 92-98, 2021 | 1316 | 2021 |
| Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 725 | 2021 |
| Differential roles for interleukin-23 and interleukin-17 in intestinal immunoregulation JR Maxwell, Y Zhang, WA Brown, CL Smith, FR Byrne, M Fiorino, ... Immunity 43 (4), 739-750, 2015 | 327 | 2015 |
| CD45 ectodomain controls interaction with GEMs and Lck activity for optimal TCR signaling C Irles, A Symons, F Michel, TR Bakker, PA van der Merwe, O Acuto Nature immunology 4 (2), 189-197, 2003 | 228 | 2003 |
| Whole-genome sequencing reveals host factors underlying critical COVID-19 A Kousathanas, E Pairo-Castineira, K Rawlik, A Stuckey, CA Odhams, ... Nature 607 (7917), 97-103, 2022 | 224 | 2022 |
| Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity JF Shelton, AJ Shastri, C Ye, CH Weldon, T Filshtein-Sonmez, D Coker, ... Nature Genetics 53 (6), 801-808, 2021 | 211 | 2021 |
| MAP kinase kinase kinases and innate immunity A Symons, S Beinke, SC Ley Trends in immunology 27 (1), 40-48, 2006 | 157 | 2006 |
| TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNFα in LPS-stimulated macrophages S Rousseau, M Papoutsopoulou, A Symons, D Cook, JM Lucocq, ... Journal of cell science 121 (2), 149-154, 2008 | 146 | 2008 |
| ABIN-2 forms a ternary complex with TPL-2 and NF-κB1 p105 and is essential for TPL-2 protein stability V Lang, A Symons, SJ Watton, J Janzen, Y Soneji, S Beinke, S Howell, ... Molecular and Cellular Biology 24 (12), 5235-5248, 2004 | 109 | 2004 |
| ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses S Papoutsopoulou, A Symons, T Tharmalingham, MP Belich, F Kaiser, ... Nature immunology 7 (6), 606-615, 2006 | 101 | 2006 |
| Characterization of the interaction between galectin-1 and lymphocyte glycoproteins CD45 and Thy-1 A Symons, D N. Cooper, AN Barclay Glycobiology 10 (6), 559-563, 2000 | 82 | 2000 |
| GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19 E Pairo-Castineira, K Rawlik, AD Bretherick, T Qi, Y Wu, I Nassiri, ... Nature 617 (7962), 764-768, 2023 | 58 | 2023 |
| Trans-ethnic analysis reveals genetic and non-genetic associations with COVID-19 susceptibility and severity JF Shelton, AJ Shastri, C Ye, CH Weldon, T Filshtein-Somnez, D Coker, ... MedRxiv, 2020.09. 04.20188318, 2020 | 50 | 2020 |
| The 23andMe COVID-19 Team; Aslibekyan, S.; et al. Trans-ancestry analysis reveals genetic and nongenetic associations with COVID-19 susceptibility and severity JF Shelton, AJ Shastri, C Ye, CH Weldon, T Filshtein-Sonmez, D Coker, ... Nat. Genet 53, 801-808, 2021 | 43 | 2021 |
| Are Th17 cells in the gut pathogenic or protective? A Symons, AL Budelsky, JE Towne Mucosal immunology 5 (1), 4-6, 2012 | 39 | 2012 |
| Domain organization of the extracellular region of CD45 A Symons, AC Willis, AN Barclay Protein engineering 12 (10), 885-892, 1999 | 31 | 1999 |
| Il-17 receptor a is required for il-17c biology AL Budelsky, JE Towne, Y Zhang, L Siegel, A Symons US Patent App. 14/234,064, 2014 | 21 | 2014 |
| STARTRAC analyses of scRNAseq data from tumor models reveal T cell dynamics and therapeutic targets D Bhatt, B Kang, D Sawant, L Zheng, K Perez, Z Huang, L Sekirov, ... Journal of Experimental Medicine 218 (6), e20201329, 2021 | 17 | 2021 |
| Discovery of [1,2,4]Triazolo[1,5-a]pyridine Derivatives as Potent and Orally Bioavailable RORγt Inverse Agonists R Nakajima, H Oono, S Sugiyama, Y Matsueda, T Ida, S Kakuda, J Hirata, ... ACS Medicinal Chemistry Letters 11 (4), 528-534, 2020 | 17 | 2020 |
| A second update on mapping the human genetic architecture of COVID-19 M Kanai, SJ Andrews, M Cordioli, C Stevens, BM Neale, M Daly, A Ganna, ... Nature 621 (7977), E7-E26, 2023 | 15 | 2023 |
