Doris Stoffers
Doris Stoffers
Perelman School of Medicine at the University of Pennsylvania
Verified email at
Cited by
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Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats.
G Xu, DA Stoffers, JF Habener, S Bonner-Weir
Diabetes 48 (12), 2270-2276, 1999
Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
DA Stoffers, NT Zinkin, V Stanojevic, WL Clarke, JF Habener
Nature genetics 15 (1), 106-110, 1997
Early-onset type-II diabetes mellitus (MODY4) linked to IPF1
D Stoffers, J Ferrer, W Clarke, J Habener
Nature Genetics 17 (2), 138-9, 1997
Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas.
DA Stoffers, TJ Kieffer, MA Hussain, DJ Drucker, S Bonner-Weir, ...
Diabetes 49 (5), 741-748, 2000
The biosynthesis of neuropeptides: peptide alpha-amidation
BA Eipper, DA Stoffers, RE Mains
Annual review of neuroscience 15 (1), 57-85, 1992
Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1
JH Park, DA Stoffers, RD Nicholls, RA Simmons
The Journal of clinical investigation 118 (6), 2316-2324, 2008
On the origin of the β cell
JM Oliver-Krasinski, DA Stoffers
Genes & development 22 (15), 1998-2021, 2008
Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice
N Habbe, G Shi, RA Meguid, V Fendrich, F Esni, H Chen, G Feldmann, ...
Proceedings of the National Academy of Sciences 105 (48), 18913-18918, 2008
Defective mutations in the insulin promoter factor-1 (IPF-1) gene in late-onset type 2 diabetes mellitus
DA Stoffers, JC Chèvre, E Durand, V Stanojevic, C Dina, JF Habener, ...
The Journal of clinical investigation 104 (9), R41-R48, 1999
Pancreatic epithelial plasticity mediated by acinar cell transdifferentiation and generation of nestin-positive intermediates
AL Means, IM Meszoely, K Suzuki, Y Miyamoto, AK Rustgi, RJ Coffey, ...
Development 132 (16), 3767-3776, 2005
Neonatal exendin-4 prevents the development of diabetes in the intrauterine growth retarded rat
DA Stoffers, BM Desai, DD DeLeon, RA Simmons
Diabetes 52 (3), 734-740, 2003
Preexisting pancreatic acinar cells contribute to acinar cell, but not islet β cell, regeneration
BM Desai, J Oliver-Krasinski, DD De Leon, C Farzad, N Hong, SD Leach, ...
The Journal of clinical investigation 117 (4), 971-977, 2007
Pdx1 maintains β cell identity and function by repressing an α cell program
T Gao, B McKenna, C Li, M Reichert, J Nguyen, T Singh, C Yang, ...
Cell metabolism 19 (2), 259-271, 2014
Vertical sleeve gastrectomy is effective in two genetic mouse models of glucagon-like Peptide 1 receptor deficiency
HE Wilson-Pérez, AP Chambers, KK Ryan, B Li, DA Sandoval, D Stoffers, ...
Diabetes 62 (7), 2380-2385, 2013
Role of endogenous glucagon-like peptide-1 in islet regeneration after partial pancreatectomy
DD De Leon, S Deng, R Madani, RS Ahima, DJ Drucker, DA Stoffers
Diabetes 52 (2), 365-371, 2003
Tissue-specific deletion of Foxa2 in pancreatic β cells results in hyperinsulinemic hypoglycemia
NJ Sund, MZ Vatamaniuk, M Casey, SL Ang, MA Magnuson, DA Stoffers, ...
Genes & development 15 (13), 1706-1715, 2001
Hedgehog signaling is required for effective regeneration of exocrine pancreas
V Fendrich, F Esni, MVR Garay, G Feldmann, N Habbe, JN Jensen, Y Dor, ...
Gastroenterology 135 (2), 621-631. e8, 2008
Insulin promoter factor-1 gene mutation linked to early-onset type 2 diabetes mellitus directs expression of a dominant negative isoprotein.
DA Stoffers, V Stanojevic, JF Habener
The Journal of clinical investigation 102 (1), 232-241, 1998
The mutant K-ras oncogene causes pancreatic periductal lymphocytic infiltration and gastric mucous neck cell hyperplasia in transgenic mice
FH Brembeck, FS Schreiber, TB Deramaudt, L Craig, B Rhoades, ...
Cancer research 63 (9), 2005-2009, 2003
A newly discovered role of transcription factors involved in pancreas development and the pathogenesis of diabetes mellitus.
JF Habener, DA Stoffers
Proceedings of the Association of American Physicians 110 (1), 12-21, 1998
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