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Luuk van Hooren
Luuk van Hooren
Unknown affiliation
Verified email at sanofi.com
Title
Cited by
Cited by
Year
Vascular targeting to increase the efficiency of immune checkpoint blockade in cancer
M Georganaki, L van Hooren, A Dimberg
Frontiers in immunology 9, 427486, 2018
1272018
Local checkpoint inhibition of CTLA‐4 as a monotherapy or in combination with anti‐PD1 prevents the growth of murine bladder cancer
L van Hooren, LC Sandin, I Moskalev, P Ellmark, A Dimberg, P Black, ...
European journal of immunology 47 (2), 385-393, 2017
742017
Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma
L van Hooren, A Vaccaro, M Ramachandran, K Vazaios, S Libard, ...
Nature Communications 12 (1), 4127, 2021
702021
Platelet-specific PDGFB ablation impairs tumor vessel integrity and promotes metastasis
Y Zhang, J Cedervall, A Hamidi, M Herre, K Viitaniemi, G D'Amico, Z Miao, ...
Cancer Research 80 (16), 3345-3358, 2020
432020
Sunitinib enhances the antitumor responses of agonistic CD40-antibody by reducing MDSCs and synergistically improving endothelial activation and T-cell recruitment
L van Hooren, M Georganaki, H Huang, SM Mangsbo, A Dimberg
Oncotarget 7 (31), 50277, 2016
412016
Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy
M Georganaki, M Ramachandran, S Tuit, NG Núñez, A Karampatzakis, ...
Oncoimmunology 9 (1), 1730538, 2020
282020
CD103+ regulatory T cells underlie resistance to radio-immunotherapy and impair CD8+ T cell activation in glioblastoma
L van Hooren, SM Handgraaf, DJ Kloosterman, E Karimi, LWHG van Mil, ...
Nature Cancer 4 (5), 665-681, 2023
192023
Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma
M Ramachandran, A Vaccaro, T van de Walle, M Georganaki, R Lugano, ...
Cancer Cell 41 (6), 1134-1151. e10, 2023
162023
Vaccination against galectin-1 promotes cytotoxic T-cell infiltration in melanoma and reduces tumor burden
J Femel, L van Hooren, M Herre, J Cedervall, F Saupe, EJM Huijbers, ...
Cancer Immunology, Immunotherapy 71 (8), 2029-2040, 2022
152022
ELTD1 deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma
H Huang, M Georganaki, LL Conze, B Laviña, L van Hooren, K Vemuri, ...
Neuro-oncology 24 (3), 398-411, 2022
102022
Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations
IK Kerzeli, M Lord, M Doroszko, R Elgendy, A Chourlia, I Stepanek, ...
Plos one 16 (7), e0253178, 2021
52021
Correction to: Vaccination against galectin-1 promotes cytotoxic T-cell infiltration in melanoma and reduces tumor burden
J Femel, L van Hooren, M Herre, J Cedervall, F Saupe, EJM Huijbers, ...
Cancer Immunology, Immunotherapy 71 (10), 2581-2581, 2022
22022
Agonistic CD40 antibody therapy induces tertiary lymphoid structures but impairs the response to immune checkpoint blockade in glioma
L van Hooren, A Vaccaro, M Ramachandran, K Vazaios, S Libard, ...
bioRxiv, 2021.01. 05.425377, 2021
22021
Abstract B103: Intralesional administration of CTLA-4 blocking monoclonal antibodies as a means to optimize bladder cancer therapy
L Hooren, L Sandin, I Moskalev, P Ellmark, A Dimberg, P Black, ...
Cancer Immunology Research 4 (11_Supplement), B103-B103, 2016
12016
CD93 maintains endothelial barrier function and limits metastatic dissemination
K Vemuri, B de Alves Pereira, P Fuenzalida, Y Subashi, S Barbera, ...
JCI insight 9 (7), 2024
2024
CD93 limits VEGFR2 activation and preserves endothelial barrier function in metastatic cancer
K Vemuri, B de Alves Pereira, P Fuenzalida, Y Subashi, L van Hooren, ...
2022
Development and characterization of a novel autochthonous semi-spontaneous bladder cancer model by pathological evaluation, single cell sequencing and proteomic profiling
IK Kerzeli, M Lord, I Stepanek, A Chourlia, E Larsson, R Elgendy, ...
Urologic Oncology: Seminars and Original Investigations 38 (12), 896, 2020
2020
Abstract A128: Tumor endothelial cells say IDO to CD40-stimulating immunotherapy
A Dimberg, A Karampatzakis, S Tuit, M Ramachandran, G Fotaki, ...
Cancer Immunology Research 7 (2_Supplement), A128-A128, 2019
2019
Abstract A159: Agonistic CD40 antibody therapy induces formation of tertiary lymphoid structures in glioma and inhibits the response to immune-checkpoint blockade
L Hooren, A Vaccaro, M Georganaki, M Ramachandran, H Huang, J Lau, ...
Cancer Immunology Research 7 (2_Supplement), A159-A159, 2019
2019
Antibody-based immunotherapy of cancer: From optimization to novel approaches
L van Hooren
Acta Universitatis Upsaliensis, 2018
2018
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