Control of mitochondrial physiology and cell death by the Bcl-2 family proteins Bax and Bok B D'Orsi, J Mateyka, JHM Prehn Neurochemistry International 109, 162-170, 2017 | 132 | 2017 |
Tau localises within mitochondrial sub-compartments and its caspase cleavage affects ER-mitochondria interactions and cellular Ca2+ handling D Cieri, M Vicario, F Vallese, B D'Orsi, P Berto, A Grinzato, C Catoni, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (10 …, 2018 | 105 | 2018 |
Calpains are downstream effectors of bax-dependent excitotoxic apoptosis B D'Orsi, H Bonner, LP Tuffy, H Düssmann, I Woods, MJ Courtney, ... Journal of Neuroscience 32 (5), 1847-1858, 2012 | 93 | 2012 |
KCa2 channels activation prevents [Ca2+] i deregulation and reduces neuronal death following glutamate toxicity and cerebral ischemia AM Dolga, N Terpolilli, F Kepura, IM Nijholt, HG Knaus, B D'orsi, ... Cell death & disease 2 (4), e147-e147, 2011 | 72 | 2011 |
Bax regulates neuronal Ca2+ homeostasis B D'Orsi, SM Kilbride, G Chen, SP Alvarez, HP Bonner, S Pfeiffer, ... Journal of Neuroscience 35 (4), 1706-1722, 2015 | 70 | 2015 |
Bok is not pro-apoptotic but suppresses poly ADP-ribose polymerase-dependent cell death pathways and protects against excitotoxic and seizure-induced neuronal injury B D'Orsi, T Engel, S Pfeiffer, S Nandi, T Kaufmann, DC Henshall, ... Journal of neuroscience 36 (16), 4564-4578, 2016 | 47 | 2016 |
Context-specific switch from anti-to pro-epileptogenic function of the P2Y1 receptor in experimental epilepsy M Alves, LDD Garcia, G Conte, EM Jimenez-Mateos, B D'Orsi, ... Journal of Neuroscience 39 (27), 5377-5392, 2019 | 37 | 2019 |
The BAX/BAK-like protein BOK is a prognostic marker in colorectal cancer S Carberry, B D’Orsi, N Monsefi, M Salvucci, O Bacon, J Fay, M Rehm, ... Cell death & disease 9 (2), 125, 2018 | 32 | 2018 |
Characterization of Puma-dependent and Puma-independent neuronal cell death pathways following prolonged proteasomal inhibition LP Tuffy, CG Concannon, B D'Orsi, MA King, I Woods, HJ Huber, ... Molecular and cellular biology 30 (23), 5484-5501, 2010 | 19 | 2010 |
BID mediates oxygen-glucose deprivation-induced neuronal injury in organotypic hippocampal slice cultures and modulates tissue inflammation in a transient focal cerebral … NA Martin, H Bonner, ML Elkjær, B D’Orsi, G Chen, HG König, ... Frontiers in cellular neuroscience 10, 14, 2016 | 17 | 2016 |
Computational analysis of AMPK-mediated neuroprotection suggests acute excitotoxic bioenergetics and glucose dynamics are regulated by a minimal set of critical reactions NMC Connolly, B D’Orsi, N Monsefi, HJ Huber, JHM Prehn PLoS One 11 (2), e0148326, 2016 | 14 | 2016 |
Kidins220/ARMS interacts with Pdzrn3, a protein containing multiple binding domains M Andreazzoli, G Gestri, E Landi, B D’Orsi, M Barilari, A Iervolino, ... Biochimie 94 (9), 2054-2057, 2012 | 14 | 2012 |
Zika virus induces FOXG1 nuclear displacement and downregulation in human neural progenitors G Lottini, M Baggiani, G Chesi, B D’Orsi, P Quaranta, M Lai, L Pancrazi, ... Stem Cell Reports 17 (7), 1683-1698, 2022 | 11 | 2022 |
AMPK‐regulated miRNA‐210‐3p is activated during ischaemic neuronal injury and modulates PI3K‐p70S6K signalling S Pfeiffer, A Tomašcová, U Mamrak, SJ Haunsberger, NMC Connolly, ... Journal of Neurochemistry 159 (4), 710-728, 2021 | 6 | 2021 |
Effect of TP53 deficiency and KRAS signaling on the bioenergetics of colon cancer cells in response to different substrates: A single cell study J Kealey, H Düssmann, I Llorente-Folch, N Niewidok, M Salvucci, ... Frontiers in Cell and Developmental Biology 10, 893677, 2022 | 5 | 2022 |
BOK controls ER proteostasis and physiological ER stress responses in neurons F Walter, B D’Orsi, A Jagannathan, H Dussmann, JHM Prehn Frontiers in Cell and Developmental Biology 10, 915065, 2022 | 3 | 2022 |
Mitochondrial Carrier Homolog 2 Functionally Co-operates With BH3 Interacting-Domain Death Agonist in Promoting Ca2+-Induced Neuronal Injury B D’Orsi, N Niewidok, H Düssmann, JHM Prehn Frontiers in Cell and Developmental Biology 9, 750100, 2021 | 3 | 2021 |
Targeting mitochondrial calcium to fight neurological deficits: Role of the MCU in the pathogenesis of Alzheimer's disease and status epilepticus B D’orsi, L Galla, E Greotti, E Beamer, T Engel, D De Stefani, T Pozzan, ... IBRO Reports 6, S368, 2019 | | 2019 |
Early dysfunction of astrocytic Ca2+ signaling in Alzheimer's Disease C Mazzola, B D’orsi, R Rizzuto, D De Stefani IBRO Reports 6, S257, 2019 | | 2019 |
Abstracts from the 5th International Conference for Healthcare and Medical Students (ICHAMS) Dublin, Ireland. 19-20 February 2016 Y Sweeney, H O’Neill, G Duffy, D Creegan, V Bustos, BJ Harvey, ... BMC Proceedings 10, 37-52, 2016 | | 2016 |