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Randall J. Kimple, M.D. Ph.D.
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G-protein signaling: back to the future
CR McCudden, MD Hains, RJ Kimple, DP Siderovski, FS Willard
Cellular and molecular life sciences 62, 551-577, 2005
7282005
Enhanced radiation sensitivity in HPV-positive head and neck cancer
RJ Kimple, MA Smith, GC Blitzer, AD Torres, JA Martin, RZ Yang, CR Peet, ...
Cancer research 73 (15), 4791-4800, 2013
4302013
Translation of Polarity Cues into Asymmetric Spindle Positioning in Caenorhabditis elegans Embryos
K Colombo, SW Grill, RJ Kimple, FS Willard, DP Siderovski, P Gönczy
Science 300 (5627), 1957-1961, 2003
3612003
Structural determinants for GoLoco-induced inhibition of nucleotide release by Gα subunits
RJ Kimple, ME Kimple, L Betts, J Sondek, DP Siderovski
Nature 416 (6883), 878-881, 2002
3022002
RGS12 and RGS14 GoLoco Motifs Are GαiInteraction Sites with Guanine Nucleotide Dissociation Inhibitor Activity
RJ Kimple, L De Vries, H Tronchere, CI Behe, RA Morris, MG Farquhar, ...
Journal of Biological Chemistry 276 (31), 29275-29281, 2001
2842001
Prevalence of human papillomavirus in oropharyngeal cancer: a systematic review
AP Stein, S Saha, JL Kraninger, AD Swick, M Yu, PF Lambert, RJ Kimple
The Cancer Journal 21 (3), 138-146, 2015
2452015
Return of the GDI: the GoLoco motif in cell division
FS Willard, RJ Kimple, DP Siderovski
Annual review of biochemistry 73 (1), 925-951, 2004
2352004
AXL mediates resistance to cetuximab therapy
TM Brand, M Iida, AP Stein, KL Corrigan, CM Braverman, N Luthar, ...
Cancer research 74 (18), 5152-5164, 2014
2122014
Association of p16INK4a overexpression with improved outcomes in young patients with squamous cell cancers of the oral tongue
SL Harris, LB Thorne, WT Seaman, D Neil Hayes, ME Couch, RJ Kimple
Head & neck 33 (11), 1622-1627, 2011
1722011
Patient-derived cancer organoid cultures to predict sensitivity to chemotherapy and radiation
CA Pasch, PF Favreau, AE Yueh, CP Babiarz, AA Gillette, JT Sharick, ...
Clinical Cancer Research 25 (17), 5376-5387, 2019
1712019
Never‐smokers, never‐drinkers: unique clinical subgroup of young patients with head and neck squamous cell cancers
SL Harris, RJ Kimple, DN Hayes, ME Couch, JG Rosenman
Head & Neck: Journal for the Sciences and Specialties of the Head and Neck …, 2010
1612010
Melanoma cells show a heterogeneous range of sensitivity to ionizing radiation and are radiosensitized by inhibition of B-RAF with PLX-4032
MJ Sambade, EC Peters, NE Thomas, WK Kaufmann, RJ Kimple, ...
Radiotherapy and Oncology 98 (3), 394-399, 2011
1512011
Clinical cancer advances 2020: annual report on progress against cancer from the American Society of Clinical Oncology
MJ Markham, K Wachter, N Agarwal, MM Bertagnolli, SM Chang, W Dale, ...
Journal of Clinical Oncology 38 (10), 1081, 2020
1432020
Review of the clinical and biologic aspects of human papillomavirus-positive squamous cell carcinomas of the head and neck
GC Blitzer, MA Smith, SL Harris, RJ Kimple
International Journal of Radiation Oncology* Biology* Physics 88 (4), 761-770, 2014
1412014
Structure-based protocol for identifying mutations that enhance protein–protein binding affinities
DW Sammond, ZM Eletr, C Purbeck, RJ Kimple, DP Siderovski, ...
Journal of molecular biology 371 (5), 1392-1404, 2007
1202007
AXL is a logical molecular target in head and neck squamous cell carcinoma
TM Brand, M Iida, AP Stein, KL Corrigan, CM Braverman, JP Coan, ...
Clinical cancer research 21 (11), 2601-2612, 2015
1192015
Human papillomavirus type 16 E7 oncoprotein causes a delay in repair of DNA damage
JW Park, KP Nickel, AD Torres, D Lee, PF Lambert, RJ Kimple
Radiotherapy and Oncology 113 (3), 337-344, 2014
1052014
Development and characterization of HPV-positive and HPV-negative head and neck squamous cell carcinoma tumorgrafts
RJ Kimple, PM Harari, AD Torres, RZ Yang, BJ Soriano, M Yu, ...
Clinical Cancer Research 19 (4), 855-864, 2013
1032013
Prevalence of human papillomavirus in oropharyngeal squamous cell carcinoma in the United States across time
AP Stein, S Saha, M Yu, RJ Kimple, PF Lambert
Chemical research in toxicology 27 (4), 462-469, 2014
1002014
The future of radiobiology
DG Kirsch, M Diehn, AH Kesarwala, A Maity, MA Morgan, JK Schwarz, ...
JNCI: Journal of the National Cancer Institute 110 (4), 329-340, 2018
962018
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