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Leia Shuhaibar
Leia Shuhaibar
Assistant Professor, University of Connecticut Health Center
Verified email at uchc.edu
Title
Cited by
Cited by
Year
Intercellular signaling via cyclic GMP diffusion through gap junctions restarts meiosis in mouse ovarian follicles
LC Shuhaibar, JR Egbert, RP Norris, PD Lampe, VO Nikolaev, ...
Proceedings of the National Academy of Sciences 112 (17), 5527-5532, 2015
1652015
Luteinizing hormone reduces the activity of the NPR2 guanylyl cyclase in mouse ovarian follicles, contributing to the cyclic GMP decrease that promotes resumption of meiosis in …
JW Robinson, M Zhang, LC Shuhaibar, RP Norris, A Geerts, F Wunder, ...
Developmental biology 366 (2), 308-316, 2012
1652012
Dephosphorylation and inactivation of NPR2 guanylyl cyclase in granulosa cells contributes to the LH-induced decrease in cGMP that causes resumption of meiosis in rat oocytes
JR Egbert, LC Shuhaibar, AB Edmund, DA Van Helden, JW Robinson, ...
Development 141 (18), 3594-3604, 2014
1132014
Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase is required for rapid resumption of oocyte meiosis in response to luteinizing hormone
LC Shuhaibar, JR Egbert, AB Edmund, TF Uliasz, DM Dickey, SP Yee, ...
Developmental biology 409 (1), 194-201, 2016
582016
Luteinizing hormone causes phosphorylation and activation of the cGMP phosphodiesterase PDE5 in rat ovarian follicles, contributing, together with PDE1 activity, to the …
JR Egbert, TF Uliasz, LC Shuhaibar, A Geerts, F Wunder, RJ Kleiman, ...
Biology of reproduction 94 (5), 110, 1-11, 2016
532016
Dephosphorylation of the NPR2 guanylyl cyclase contributes to inhibition of bone growth by fibroblast growth factor
JLA Shuhaibar LC1, Robinson JW2, Vigone G1, Shuhaibar NP1, Egbert JR1, Baena ...
eLife, 2017
312017
Multiple cAMP phosphodiesterases act together to prevent premature oocyte meiosis and ovulation
G Vigone, LC Shuhaibar, JR Egbert, TF Uliasz, MA Movsesian, LA Jaffe
Endocrinology 159 (5), 2142-2152, 2018
192018
Phosphatase inhibition by LB-100 enhances BMN-111 stimulation of bone growth
LC Shuhaibar, N Kaci, JR Egbert, T Horville, L Loisay, G Vigone, ...
JCI insight 6 (9), 2021
102021
The phosphatase inhibitor LB-100 acts synergistically with the NPR2 agonist BMN-111 to improve bone growth
LC Shuhaibar, N Kaci, JR Egbert, L Loisay, G Vigone, TF Uliasz, ...
bioRxiv, 2020.09. 10.288589, 2020
12020
Preparing for Fertilization: Intercellular Signals for Oocyte Maturation
LC Shuhaibar, DJ Carroll, LA Jaffe
Reproductive and Developmental Strategies: The Continuity of Life, 535-548, 2018
12018
Luteinizing Hormone Reduces Guanylyl Cyclase Activity in the Granulosa Cells of the Mouse Ovary, Leading to the Resumption of Meiosis in the Oocyte
JW Robinson, LC Shuhaibar, JJ Eppig, LR Potter, LA Jaffe
Molecular Biology of the Cell 22, 2011
12011
A new combination therapy for the treatment of fgfr3-related skeletal disease
L Legeai-Mallet, L Jaffe, L Shuhaibar
US Patent App. 18/003,783, 2023
2023
FGF-inhibition of NPR2-mediated Cyclic cGMP Production in Growth Plate Chondrocytes Is Reversed by the Phosphatase Inhibitor LB-100
LC Shuhaibar, G Vigone, LA Jaffe
JOURNAL OF BONE AND MINERAL RESEARCH 33, 196-197, 2018
2018
Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications: Bamberg, Germany. 23-25 June, 2017
G Todd Milne, Ironwood team, P Sandner, KA Lincoln, PC Harrison, ...
BMC Pharmacology and Toxicology 18, 1-35, 2017
2017
Luteinizing Hormone Causes Phosphorylation and Activation of the cyclic GMP Phosphodiesterase PDE5 in Rat Ovarian Follicles, Contributing, Together with PDE1 Activity, to the …
JR Egbert, TF Uliasz, LC Shuhaibar, A Geerts, F Wunder, RJ Kleiman, ...
2016
Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase regulates oocyte meiotic resumption
LC Shuhaibar, AB Edmund, JR Egbert, SP Yee, LR Potter, LA Jaffe
BMC Pharmacology and Toxicology 16, 1-2, 2015
2015
Hormonal Control of Meiosis by Cyclic GMP and the Guanylyl Cyclase NPR2 in the Mouse Ovarian Follicle
LC Shuhaibar
2015
cGMP indicator mice: Generation, characterization and first in vivo results
M Thunemann, W Lai, S Feil, B Birk, M Russwurm, L Shuhaibar, L Jaffe, ...
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY 387, S20-S20, 2014
2014
Cyclic GMP-mediated intercellular communication in mammalian ovarian follicles
LA Jaffe, JR Egbert, LC Shuhaibar, L Wen, M Thunemann, R Feil, ...
BMC Pharmacology and Toxicology 14, 1-2, 2013
2013
Regulation of MAPK and MEK During Maturation and Fertilization of the Sea Star
LC Shuhaibar
Florida Institute of Technology, 2009
2009
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Articles 1–20