Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET EB Rankin, KC Fuh, L Castellini, K Viswanathan, EC Finger, AN Diep, ... Proceedings of the National Academy of Sciences 111 (37), 13373-13378, 2014 | 271 | 2014 |
Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys MS Kariolis, RC Wells, JA Getz, W Kwan, CS Mahon, R Tong, DJ Kim, ... Science translational medicine 12 (545), eaay1359, 2020 | 218 | 2020 |
Reprogramming the immunological microenvironment through radiation and targeting Axl TA Aguilera, M Rafat, L Castellini, H Shehade, MS Kariolis, ABY Hui, ... Nature communications 7 (1), 13898, 2016 | 168 | 2016 |
Carbon nanotubes increase the electrical conductivity of fibroblast-seeded collagen hydrogels RA MacDonald, CM Voge, M Kariolis, JP Stegemann Acta biomaterialia 4 (6), 1583-1592, 2008 | 160 | 2008 |
An engineered Axl'decoy receptor'effectively silences the Gas6-Axl signaling axis MS Kariolis, YR Miao, DS Jones, S Kapur, II Mathews, AJ Giaccia, ... Nature chemical biology 10 (11), 977-983, 2014 | 147 | 2014 |
Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice JC Ullman, A Arguello, JA Getz, A Bhalla, CS Mahon, J Wang, T Giese, ... Science Translational Medicine 12 (545), eaay1163, 2020 | 143 | 2020 |
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic T Logan, MJ Simon, A Rana, GM Cherf, A Srivastava, SS Davis, RLY Low, ... Cell 184 (18), 4651-4668. e25, 2021 | 113 | 2021 |
Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies MS Kariolis, YR Miao, A Diep, SE Nash, MM Olcina, D Jiang, DS Jones, ... The Journal of clinical investigation 127 (1), 183-198, 2017 | 111 | 2017 |
Directional conductivity in SWNT‐collagen‐fibrin composite biomaterials through strain‐induced matrix alignment CM Voge, M Kariolis, RA MacDonald, JP Stegemann Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2008 | 80 | 2008 |
Beyond antibodies: using biological principles to guide the development of next-generation protein therapeutics MS Kariolis, S Kapur, JR Cochran Current opinion in biotechnology 24 (6), 1072-1077, 2013 | 57 | 2013 |
Inhibition of AXL signaling in anti-metastatic therapy AJ Giaccia, EB Rankin, JR Cochran, D Jones, M Kariolis, K Fuh, Y Miao US Patent 8,618,254, 2013 | 54 | 2013 |
Cystine‐knot peptides engineered with specificities for αIIbβ3 or αIIbβ3 and αvβ3 integrins are potent inhibitors of platelet aggregation AP Silverman, MS Kariolis, JR Cochran Journal of Molecular Recognition 24 (1), 127-135, 2011 | 47 | 2011 |
Molecular architecture determines brain delivery of a transferrin receptor–targeted lysosomal enzyme A Arguello, CS Mahon, MEK Calvert, D Chan, JC Dugas, ME Pizzo, ... Journal of Experimental Medicine 219 (3), e20211057, 2022 | 43 | 2022 |
Neutralization of PD-L2 is essential for overcoming immune checkpoint blockade resistance in ovarian cancer YR Miao, KN Thakkar, J Qian, MS Kariolis, W Huang, S Nandagopal, ... Clinical cancer research 27 (15), 4435-4448, 2021 | 43 | 2021 |
Engineering high affinity protein–protein interactions using a high-throughput microcapillary array platform S Lim, B Chen, MS Kariolis, IK Dimov, TM Baer, JR Cochran ACS Chemical Biology 12 (2), 336-341, 2017 | 18 | 2017 |
Engineered polypeptides X Chen, M Kariolis, RC Wells US Patent 10,457,717, 2019 | 14 | 2019 |
Cystine knot peptides binding to alpha IIb beta 3 integrins and methods of use JR Cochran, AP Silverman, MS Kariolis US Patent 8,778,888, 2014 | 13 | 2014 |
Induced tumor heterogeneity reveals factors informing radiation and immunotherapy combinations TA Aguilera, EA Elghonaimy, H Shehade, M Rafat, L Castellini, D Jiang, ... Clinical Cancer Research 26 (12), 2972-2985, 2020 | 12 | 2020 |
31st annual meeting and associated programs of the society for immunotherapy of cancer (Sitc 2016): Part two: National harbor, md, USA. 9-13 November 2016 C Ager, M Reilley, C Nicholas, T Bartkowiak, A Jaiswal, M Curran, ... Journal for ImmunoTherapy of Cancer 4, 107-221, 2016 | 12 | 2016 |
Inhibition of AXL signaling in anti-metastatic therapy AJ Giaccia, EB Rankin, JR Cochran, D Jones, M Kariolis, K Fuh, Y Miao US Patent 9,074,192, 2015 | 12 | 2015 |