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Max Jan
Max Jan
Massachusetts General Hospital
Verified email at partners.org - Homepage
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Cited by
Cited by
Year
Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma
MP Chao, AA Alizadeh, C Tang, JH Myklebust, B Varghese, S Gill, M Jan, ...
Cell 142 (5), 699-713, 2010
11482010
Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia
M Jan, TM Snyder, MR Corces-Zimmerman, P Vyas, IL Weissman, ...
Science translational medicine 4 (149), 149ra118-149ra118, 2012
8422012
Therapeutic antibody targeting of CD47 eliminates human acute lymphoblastic leukemia
MP Chao, AA Alizadeh, C Tang, M Jan, R Weissman-Tsukamoto, F Zhao, ...
Cancer research 71 (4), 1374-1384, 2011
4462011
COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis
LB Watkin, B Jessen, W Wiszniewski, TJ Vece, M Jan, Y Sha, M Thamsen, ...
Nature genetics 47 (6), 654-660, 2015
3362015
Prospective separation of normal and leukemic stem cells based on differential expression of TIM3, a human acute myeloid leukemia stem cell marker
M Jan, MP Chao, AC Cha, AA Alizadeh, AJ Gentles, IL Weissman, ...
Proceedings of the National Academy of Sciences 108 (12), 5009-5014, 2011
3182011
The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K
M Słabicki, Z Kozicka, G Petzold, YD Li, M Manojkumar, RD Bunker, ...
Nature 585 (7824), 293-297, 2020
2482020
CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours
RC Larson, MC Kann, SR Bailey, NJ Haradhvala, PM Llopis, AA Bouffard, ...
Nature 604 (7906), 563-570, 2022
1792022
Clonal evolution of acute leukemia genomes
M Jan, R Majeti
Oncogene 32 (2), 135-140, 2013
1782013
Reversible ON-and OFF-switch chimeric antigen receptors controlled by lenalidomide
M Jan, I Scarfò, RC Larson, A Walker, A Schmidts, AA Guirguis, JA Gasser, ...
Science translational medicine 13 (575), eabb6295, 2021
1582021
The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO
G Rizki, TN Iwata, J Li, CG Riedel, CL Picard, M Jan, CT Murphy, SS Lee
PLoS genetics 7 (9), e1002235, 2011
1372011
Clonal hematopoiesis
M Jan, BL Ebert, S Jaiswal
Seminars in hematology 54 (1), 43-50, 2017
1322017
Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma
NJ Haradhvala, MB Leick, K Maurer, SH Gohil, RC Larson, N Yao, ...
Nature medicine 28 (9), 1848-1859, 2022
972022
Cancer therapies based on targeted protein degradation—lessons learned with lenalidomide
M Jan, AS Sperling, BL Ebert
Nature Reviews Clinical Oncology 18 (7), 401-417, 2021
782021
Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia
MB Leick, H Silva, I Scarfò, R Larson, BD Choi, AA Bouffard, K Gallagher, ...
Cancer cell 40 (5), 494-508. e5, 2022
622022
Recurrent genetic HLA loss in AML relapsed after matched unrelated allogeneic hematopoietic cell transplantation
M Jan, MJ Leventhal, EA Morgan, JC Wengrod, A Nag, SD Drinan, ...
Blood Advances 3 (14), 2199-2204, 2019
602019
Clonal hematopoiesis in patients receiving chimeric antigen receptor T-cell therapy
PG Miller, AS Sperling, EJ Brea, MB Leick, GG Fell, M Jan, SH Gohil, ...
Blood advances 5 (15), 2982-2986, 2021
542021
Patterns of substrate affinity, competition, and degradation kinetics underlie biological activity of thalidomide analogs
AS Sperling, M Burgess, H Keshishian, JA Gasser, S Bhatt, M Jan, ...
Blood, The Journal of the American Society of Hematology 134 (2), 160-170, 2019
502019
Efficacy and Safety of Dasatinib in Patients with Chronic Myeloid Leukemia in Blast Phase Whose Disease Is Resistant or Intolerant to Imatinib: 2-Year Follow-Up Data from the …
C Gambacorti, J Cortes, DW Kim, H Dombret, C Zhu, JMA Van Tornout, ...
Blood 110 (11), 472, 2007
302007
Clonal hematopoiesis is associated with protection from Alzheimer’s disease
H Bouzid, JA Belk, M Jan, Y Qi, C Sarnowski, S Wirth, L Ma, MR Chrostek, ...
Nature Medicine 29 (7), 1662-1670, 2023
292023
Proteolysis-targeting chimeras with reduced off-targets
TM Nguyen, V Sreekanth, A Deb, P Kokkonda, PK Tiwari, KA Donovan, ...
Nature Chemistry 16 (2), 218-228, 2024
152024
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