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James D Griffin
James D Griffin
Dana-Farber Cancer Institute
Verified email at dfci.harvard.edu
Title
Cited by
Cited by
Year
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
RL Levine, M Wadleigh, J Cools, BL Ebert, G Wernig, BJP Huntly, ...
Cancer cell 7 (4), 387-397, 2005
38112005
A Tyrosine Kinase Created by Fusion of the PDGFRA and FIP1L1 Genes as a Therapeutic Target of Imatinib in Idiopathic Hypereosinophilic Syndrome
J Cools, DJ DeAngelo, J Gotlib, EH Stover, RD Legare, J Cortes, J Kutok, ...
New England Journal of Medicine 348 (13), 1201-1214, 2003
21422003
The roles of FLT3 in hematopoiesis and leukemia
DG Gilliland, JD Griffin
Blood, The Journal of the American Society of Hematology 100 (5), 1532-1542, 2002
20172002
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
E Weisberg, PW Manley, W Breitenstein, J Brüggen, SW Cowan-Jacob, ...
Cancer cell 7 (2), 129-141, 2005
19122005
Nilotinib in imatinib-resistant CML and Philadelphia chromosome–positive ALL
H Kantarjian, F Giles, L Wunderle, K Bhalla, S O'Brien, B Wassmann, ...
New England Journal of Medicine 354 (24), 2542-2551, 2006
16302006
Granulocyte colony-stimulating factor and its receptor
GD Demetri, JD Griffin
13841991
The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element
JA DeCaprio, JW Ludlow, D Lynch, Y Furukawa, J Griffin, ...
Cell 58 (6), 1085-1095, 1989
11911989
STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications
DA Tuveson, NA Willis, T Jacks, JD Griffin, S Singer, CDM Fletcher, ...
Oncogene 20 (36), 5054-5058, 2001
8742001
Effect of recombinant human granulocyte-macrophage colony-stimulating factor on chemotherapy-induced myelosuppression
KS Antman, JD Griffin, A Elias, MA Socinski, L Ryan, SA Cannistra, ...
New England Journal of Medicine 319 (10), 593-598, 1988
8451988
Patients with acute myeloid leukemia and an activating mutation in FLT3 respond to a small-molecule FLT3 tyrosine kinase inhibitor, PKC412
RM Stone, DJ DeAngelo, V Klimek, I Galinsky, E Estey, SD Nimer, ...
Blood 105 (1), 54-60, 2005
8402005
Second generation inhibitors of BCR-ABL for the treatment of imatinib-resistant chronic myeloid leukaemia
E Weisberg, PW Manley, SW Cowan-Jacob, A Hochhaus, JD Griffin
Nature Reviews Cancer 7 (5), 345-356, 2007
8102007
Reduction of experimental canine myocardial reperfusion injury by a monoclonal antibody (anti-Mo1, anti-CD11b) that inhibits leukocyte adhesion.
PJ Simpson, RF Todd, JC Fantone, JK Mickelson, JD Griffin, BR Lucchesi
The Journal of clinical investigation 81 (2), 624-629, 1988
8091988
Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412
E Weisberg, C Boulton, LM Kelly, P Manley, D Fabbro, T Meyer, ...
Cancer cell 1 (5), 433-443, 2002
7332002
Granulocyte-macrophage colony stimulating factor expands the circulating haemopoietic progenitor cell compartment in man
MA Socinski, A Elias, L Schnipper, SA Cannistra, KH Antman, JD Griffin
The Lancet 331 (8596), 1194-1198, 1988
7281988
MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors
L Wu, JC Aster, SC Blacklow, R Lake, S Artavanis-Tsakonas, JD Griffin
Nature genetics 26 (4), 484-489, 2000
7222000
Expression of myeloid differentiation antigens on normal and malignant myeloid cells.
JD Griffin, J Ritz, LM Nadler, SF Schlossman
The Journal of clinical investigation 68 (4), 932-941, 1981
6281981
t (11; 19)(q21; p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway
G Tonon, S Modi, L Wu, A Kubo, AB Coxon, T Komiya, K O'Neil, K Stover, ...
Nature genetics 33 (2), 208-213, 2003
6172003
Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl.
N Carlesso, DA Frank, JD Griffin
The Journal of experimental medicine 183 (3), 811-820, 1996
6081996
AMN107 (nilotinib): a novel and selective inhibitor of BCR-ABL
E Weisberg, P Manley, J Mestan, S Cowan-Jacob, A Ray, JD Griffin
British journal of cancer 94 (12), 1765-1769, 2006
5902006
JAK2 associates with the βc chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region
FW Quelle, N Sato, BA Witthuhn, RC Inhorn, M Eder, A Miyajima, ...
Molecular and cellular biology, 1994
5901994
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