| Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts G Guaitoli, F Raimondi, BK Gilsbach, Y Gómez-Llorente, E Deyaert, ... Proceedings of the National Academy of Sciences 113 (30), E4357-E4366, 2016 | 157 | 2016 |
| Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations BK Gilsbach, FY Ho, IR Vetter, PJM Van Haastert, A Wittinghofer, ... Proceedings of the National Academy of Sciences 109 (26), 10322-10327, 2012 | 114 | 2012 |
| Structural biology of the LRRK2 GTPase and kinase domains: implications for regulation BK Gilsbach, A Kortholt Frontiers in molecular neuroscience 7, 32, 2014 | 108 | 2014 |
| Coordinated Ras and Rac activity shapes macropinocytic cups and enables phagocytosis of geometrically diverse bacteria CM Buckley, H Pots, A Gueho, JH Vines, CJ Munn, BA Phillips, ... Current Biology 30 (15), 2912-2926. e5, 2020 | 40 | 2020 |
| Revisiting the Roco G-protein cycle S Terheyden, FY Ho, BK Gilsbach, A Wittinghofer, A Kortholt Biochemical Journal 465 (1), 139-147, 2015 | 40 | 2015 |
| Structural characterization of LRRK2 inhibitors BK Gilsbach, AC Messias, G Ito, M Sattler, DR Alessi, A Wittinghofer, ... Journal of medicinal chemistry 58 (9), 3751-3756, 2015 | 37 | 2015 |
| Conformational heterogeneity of the Roc domains in C. tepidum Roc–COR and implications for human LRRK2 Parkinson mutations K Rudi, FY Ho, BK Gilsbach, H Pots, A Wittinghofer, A Kortholt, JP Klare Bioscience reports 35 (5), e00254, 2015 | 31 | 2015 |
| Allosteric inhibition of Parkinson’s-linked LRRK2 by constrained peptides LG Helton, A Soliman, F von Zweydorf, M Kentros, JT Manschwetus, ... ACS chemical biology 16 (11), 2326-2338, 2021 | 19 | 2021 |
| Biochemical and kinetic properties of the complex Roco G-protein cycle L Wauters, S Terheyden, BK Gilsbach, M Leemans, PS Athanasopoulos, ... Biological Chemistry 399 (12), 1447-1456, 2018 | 17 | 2018 |
| Regulation of LRRK2: insights from structural and biochemical analysis BK Gilsbach, M Eckert, CJ Gloeckner Biological chemistry 399 (7), 637-642, 2018 | 15 | 2018 |
| First model of dimeric LRRK2: the challenge of unrevealing the structure of a multidomain Parkinson's-associated protein G Guaitoli, BK Gilsbach, F Raimondi, CJ Gloeckner Biochemical Society Transactions 44 (6), 1635-1641, 2016 | 12 | 2016 |
| Dictyostelium discoideum: a model system to study LRRK2-mediated parkinson disease A Kortholt, B Gilsbach, PJM van Haastert Mechanisms in Parkinson’s Disease–Models and Treatments. Croatia: InTech …, 2012 | 8 | 2012 |
| C2GAP2 is a common regulator of Ras signaling for chemotaxis, phagocytosis, and macropinocytosis X Xu, H Pots, BK Gilsbach, D Parsons, DM Veltman, SG Ramachandra, ... Frontiers in immunology 13, 1075386, 2022 | 5 | 2022 |
| Intramolecular feedback regulation of the LRRK2 Roc G domain by a LRRK2 kinase dependent mechanism BK Gilsbach, FY Ho, B Riebenbauer, X Zhang, G Guaitoli, A Kortholt, ... BioRxiv, 2023.07. 31.549909, 2023 | 3 | 2023 |
