Genetic and epigenetic stability of human pluripotent stem cells RJ Lund, E Närvä, R Lahesmaa Nature Reviews Genetics 13 (10), 732-744, 2012 | 309 | 2012 |
Gut microbiota as an epigenetic regulator: pilot study based on whole-genome methylation analysis H Kumar, R Lund, A Laiho, K Lundelin, RE Ley, E Isolauri, S Salminen MBio 5 (6), 10.1128/mbio. 02113-14, 2014 | 209 | 2014 |
Genome-wide profiling of interleukin-4 and STAT6 transcription factor regulation of human Th2 cell programming LL Elo, H Järvenpää, S Tuomela, S Raghav, H Ahlfors, K Laurila, B Gupta, ... Immunity 32 (6), 852-862, 2010 | 179 | 2010 |
Identification of novel IL-4/Stat6-regulated genes in T lymphocytes Z Chen, R Lund, T Aittokallio, M Kosonen, O Nevalainen, R Lahesmaa The Journal of Immunology 171 (7), 3627-3635, 2003 | 138 | 2003 |
Early target genes of IL-12 and STAT4 signaling in th cells RJ Lund, Z Chen, J Scheinin, R Lahesmaa The Journal of Immunology 172 (11), 6775-6782, 2004 | 127 | 2004 |
Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell-type specificity B Hrdlickova, V Kumar, K Kanduri, DV Zhernakova, S Tripathi, ... Genome medicine 6, 1-14, 2014 | 120 | 2014 |
Global chromatin state analysis reveals lineage-specific enhancers during the initiation of human T helper 1 and T helper 2 cell polarization RD Hawkins, A Larjo, SK Tripathi, U Wagner, Y Luu, T Lönnberg, ... Immunity 38 (6), 1271-1284, 2013 | 111 | 2013 |
Identification of genes involved in the initiation of human Th1 or Th2 cell commitment R Lund, H Ahlfors, E Kainonen, AM Lahesmaa, C Dixon, R Lahesmaa European journal of immunology 35 (11), 3307-3319, 2005 | 106 | 2005 |
Expression of human pim family genes is selectively up‐regulated by cytokines promoting T helper type 1, but not T helper type 2, cell differentiation TLT Aho, RJ Lund, EK Ylikoski, S Matikainen, R Lahesmaa, PJ Koskinen Immunology 116 (1), 82-88, 2005 | 105 | 2005 |
Genome-wide identification of novel genes involved in early Th1 and Th2 cell differentiation RJ Lund, M Löytömäki, T Naumanen, C Dixon, Z Chen, H Ahlfors, ... The Journal of Immunology 178 (6), 3648-3660, 2007 | 103 | 2007 |
Identification of novel genes regulated by IL-12, IL-4, or TGF-β during the early polarization of CD4+ lymphocytes R Lund, T Aittokallio, O Nevalainen, R Lahesmaa The Journal of Immunology 171 (10), 5328-5336, 2003 | 97 | 2003 |
RNA‐Binding Protein L1TD1 Interacts with LIN28 via RNA and is Required for Human Embryonic Stem Cell Self‐Renewal and Cancer Cell Proliferation E Närvä, N Rahkonen, MR Emani, R Lund, JP Pursiheimo, J Nästi, ... Stem cells 30 (3), 452-460, 2012 | 94 | 2012 |
IL‐12 up‐regulates T‐bet independently of IFN‐γ in human CD4+ T cells E Ylikoski, R Lund, M Kyläniemi, S Filén, M Kilpeläinen, J Savolainen, ... European journal of immunology 35 (11), 3297-3306, 2005 | 88 | 2005 |
DNA methylation and transcriptome changes associated with cisplatin resistance in ovarian cancer RJ Lund, K Huhtinen, J Salmi, J Rantala, EV Nguyen, R Moulder, ... Scientific reports 7 (1), 1469, 2017 | 80 | 2017 |
IFN-α and IL-12 activate IFN regulatory factor 1 (IRF-1), IRF-4, and IRF-8 gene expression in human NK and T cells A Lehtonen, R Lund, R Lahesmaa, I Julkunen, T Sareneva, S Matikainen Cytokine 24 (3), 81-90, 2003 | 78 | 2003 |
The impact of probiotic supplementation during pregnancy on DNA methylation of obesity-related genes in mothers and their children S Vähämiko, A Laiho, R Lund, E Isolauri, S Salminen, K Laitinen European journal of nutrition 58, 367-377, 2019 | 69 | 2019 |
Notch signaling regulates the differentiation of neural crest from human pluripotent stem cells P Noisa, C Lund, K Kanduri, R Lund, H Lähdesmäki, R Lahesmaa, ... Journal of Cell Science 127 (9), 2083-2094, 2014 | 59 | 2014 |
Continuous hypoxic culturing of human embryonic stem cells enhances SSEA-3 and MYC levels E Närvä, JP Pursiheimo, A Laiho, N Rahkonen, MR Emani, M Viitala, ... PloS one 8 (11), e78847, 2013 | 57 | 2013 |
Early detection of peripheral blood cell signature in children developing β-cell autoimmunity at a young age H Kallionpää, J Somani, S Tuomela, U Ullah, R De Albuquerque, ... Diabetes 68 (10), 2024-2034, 2019 | 53 | 2019 |
High-throughput karyotyping of human pluripotent stem cells RJ Lund, T Nikula, N Rahkonen, E Närvä, D Baker, N Harrison, ... Stem cell research 9 (3), 192-195, 2012 | 53 | 2012 |