Pasi Janne
Pasi Janne
Dana Farber Cancer Institute
Verified email at
Cited by
Cited by
EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy
JG Paez, PA Janne, JC Lee, S Tracy, H Greulich, S Gabriel, P Herman, ...
Science 304 (5676), 1497-1500, 2004
MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling
JA Engelman, K Zejnullahu, T Mitsudomi, Y Song, C Hyland, JO Park, ...
science 316 (5827), 1039-1043, 2007
Anaplastic lymphoma kinase inhibition in non–small-cell lung cancer
EL Kwak, YJ Bang, DR Camidge, AT Shaw, B Solomon, RG Maki, SHI Ou, ...
New England Journal of Medicine 363 (18), 1693-1703, 2010
EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib
S Kobayashi, TJ Boggon, T Dayaram, PA Jšnne, O Kocher, M Meyerson, ...
New England Journal of Medicine 352 (8), 786-792, 2005
The landscape of somatic copy-number alteration across human cancers
R Beroukhim, CH Mermel, D Porter, G Wei, S Raychaudhuri, J Donovan, ...
Nature 463 (7283), 899-905, 2010
Crizotinib versus Chemotherapy in Advanced ALK-Positive Lung Cancer
AT Shaw, DW Kim, K Nakagawa, T Seto, L Crinů, MJ Ahn, T De Pas, ...
New England Journal of Medicine 368 (25), 2385-2394, 2013
AZD9291 in EGFR inhibitor–resistant non–small-cell lung cancer
PA Jšnne, JCH Yang, DW Kim, D Planchard, Y Ohe, SS Ramalingam, ...
New England Journal of Medicine 372 (18), 1689-1699, 2015
Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing
M Imielinski, AH Berger, PS Hammerman, B Hernandez, TJ Pugh, ...
Cell 150 (6), 1107-1120, 2012
Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non–small-cell lung cancer treated with chemotherapy†…
DA Eberhard, BE Johnson, LC Amler, AD Goddard, SL Heldens, ...
Journal of clinical oncology 23 (25), 5900-5909, 2005
Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study
DR Camidge, YJ Bang, EL Kwak, AJ Iafrate, M Varella-Garcia, SB Fox, ...
The lancet oncology 13 (10), 1011-1019, 2012
Acquired EGFR C797S mutation mediates resistance to AZD9291 in non–small cell lung cancer harboring EGFR T790M
KS Thress, CP Paweletz, E Felip, BC Cho, D Stetson, B Dougherty, Z Lai, ...
Nature medicine 21 (6), 560-562, 2015
Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints
S Koyama, EA Akbay, YY Li, GS Herter-Sprie, KA Buczkowski, ...
Nature communications 7 (1), 10501, 2016
Activation of the PD-1 Pathway Contributes to Immune Escape in EGFR-Driven Lung TumorsImmune Escape of EGFR-Mutant Tumors through PD-1
EA Akbay, S Koyama, J Carretero, A Altabef, JH Tchaicha, ...
Cancer discovery 3 (12), 1355-1363, 2013
Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC
AB Turke, K Zejnullahu, YL Wu, Y Song, D Dias-Santagata, E Lifshits, ...
Cancer cell 17 (1), 77-88, 2010
EML4-ALK Fusion Gene and Efficacy of an ALK Kinase Inhibitor in Lung Cancer
JP Koivunen, C Mermel, K Zejnullahu, C Murphy, E Lifshits, AJ Holmes, ...
Clinical cancer research 14 (13), 4275-4283, 2008
LKB1 modulates lung cancer differentiation and metastasis
H Ji, MR Ramsey, DN Hayes, C Fan, K McNamara, P Kozlowski, C Torrice, ...
Nature 448 (7155), 807-810, 2007
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
W Zhou, D Ercan, L Chen, CH Yun, D Li, M Capelletti, AB Cortot, ...
Nature 462 (7276), 1070-1074, 2009
STK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant Lung AdenocarcinomaSTK11/LKB1 Mutations and PD-1 Inhibitor Resistance in KRAS-Mutant LUAC
F Skoulidis, ME Goldberg, DM Greenawalt, MD Hellmann, MM Awad, ...
Cancer discovery 8 (7), 822-835, 2018
First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations
LV Sequist, RG Martins, D Spigel, SM Grunberg, A Spira, PA Janne, ...
Journal of clinical oncology 26 (15), 2442-2449, 2008
The quest to overcome resistance to EGFR-targeted therapies in cancer
CR Chong, PA Jšnne
Nature medicine 19 (11), 1389-1400, 2013
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