| Anti-PD-1 and anti-CTLA-4 therapies in cancer: mechanisms of action, efficacy, and limitations JA Seidel, A Otsuka, K Kabashima Frontiers in oncology 8, 86, 2018 | 1263 | 2018 |
| Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndromes via inflammasome activation FL Zhong, O Mamaï, L Sborgi, L Boussofara, R Hopkins, K Robinson, ... Cell 167 (1), 187-202. e17, 2016 | 394 | 2016 |
| Activated regulatory T cells are the major T cell type emigrating from the skin during a cutaneous immune response in mice M Tomura, T Honda, H Tanizaki, A Otsuka, G Egawa, Y Tokura, ... The Journal of clinical investigation 120 (3), 883-893, 2010 | 313 | 2010 |
| The epithelial immune microenvironment (EIME) in atopic dermatitis and psoriasis T Dainichi, A Kitoh, A Otsuka, S Nakajima, T Nomura, DH Kaplan, ... Nature immunology 19 (12), 1286-1298, 2018 | 287 | 2018 |
| Langerhans cells are critical in epicutaneous sensitization with protein antigen via thymic stromal lymphopoietin receptor signaling S Nakajima, BZ Igyártó, T Honda, G Egawa, A Otsuka, M Hara-Chikuma, ... Journal of Allergy and Clinical Immunology 129 (4), 1048-1055. e6, 2012 | 264 | 2012 |
| The Janus kinase inhibitor JTE-052 improves skin barrier function through suppressing signal transducer and activator of transcription 3 signaling W Amano, S Nakajima, H Kunugi, Y Numata, A Kitoh, G Egawa, ... Journal of Allergy and Clinical Immunology 136 (3), 667-677. e7, 2015 | 235 | 2015 |
| Perivascular leukocyte clusters are essential for efficient activation of effector T cells in the skin Y Natsuaki, G Egawa, S Nakamizo, S Ono, S Hanakawa, T Okada, ... Nature immunology 15 (11), 1064-1069, 2014 | 219 | 2014 |
| IL-17A as an inducer for Th2 immune responses in murine atopic dermatitis models S Nakajima, A Kitoh, G Egawa, Y Natsuaki, S Nakamizo, CS Moniaga, ... Journal of Investigative Dermatology 134 (8), 2122-2130, 2014 | 175 | 2014 |
| The etiopathogenesis of atopic dermatitis: barrier disruption, immunological derangement, and pruritus P Rerknimitr, A Otsuka, C Nakashima, K Kabashima Inflammation and regeneration 37, 1-15, 2017 | 170 | 2017 |
| The interplay between genetic and environmental factors in the pathogenesis of atopic dermatitis A Otsuka, T Nomura, P Rerknimitr, JA Seidel, T Honda, K Kabashima Immunological reviews 278 (1), 246-262, 2017 | 165 | 2017 |
| Requirement of interaction between mast cells and skin dendritic cells to establish contact hypersensitivity A Otsuka, M Kubo, T Honda, G Egawa, S Nakajima, H Tanizaki, B Kim, ... PloS one 6 (9), e25538, 2011 | 157 | 2011 |
| Flaky tail mouse denotes human atopic dermatitis in the steady state and by topical application with Dermatophagoides pteronyssinus extract CS Moniaga, G Egawa, H Kawasaki, M Hara-Chikuma, T Honda, ... The American journal of pathology 176 (5), 2385-2393, 2010 | 137 | 2010 |
| Tumour hypoxia promotes melanoma growth and metastasis via High Mobility Group Box-1 and M2-like macrophages R Huber, B Meier, A Otsuka, G Fenini, T Satoh, S Gehrke, D Widmer, ... Scientific reports 6 (1), 29914, 2016 | 130 | 2016 |
| Interleukin‐31 and interleukin‐31 receptor: new therapeutic targets for atopic dermatitis C Nakashima, A Otsuka, K Kabashima Experimental Dermatology 27 (4), 327-331, 2018 | 129 | 2018 |
| Basophils are required for the induction of Th2 immunity to haptens and peptide antigens A Otsuka, S Nakajima, M Kubo, G Egawa, T Honda, A Kitoh, T Nomura, ... Nature communications 4 (1), 1738, 2013 | 125 | 2013 |
| Serum level of interleukin-6 is increased in nivolumab-associated psoriasiform dermatitis and tumor necrosis factor-α is a biomarker of nivolumab recativity R Tanaka, N Okiyama, M Okune, Y Ishitsuka, R Watanabe, J Furuta, ... Journal of dermatological science 86 (1), 71-73, 2017 | 123 | 2017 |
| Cutaneous angiosarcoma: update on biology and latest treatment Y Ishida, A Otsuka, K Kabashima Current opinion in oncology 30 (2), 107-112, 2018 | 115 | 2018 |
| Resolvin E1 inhibits dendritic cell migration in the skin and attenuates contact hypersensitivity responses Y Sawada, T Honda, S Hanakawa, S Nakamizo, T Murata, ... Journal of Experimental Medicine 212 (11), 1921-1930, 2015 | 112 | 2015 |
| Hedgehog pathway inhibitors promote adaptive immune responses in basal cell carcinoma A Otsuka, J Dreier, PF Cheng, M Nägeli, H Lehmann, L Felderer, IJ Frew, ... Clinical Cancer Research 21 (6), 1289-1297, 2015 | 112 | 2015 |
| Incidence, features, and prognosis of immune-related adverse events involving the thyroid gland induced by nivolumab I Yamauchi, A Yasoda, S Matsumoto, Y Sakamori, YH Kim, M Nomura, ... PLoS One 14 (5), e0216954, 2019 | 111 | 2019 |
