| Inhibition of transient receptor potential A1 channel by phosphatidylinositol-4, 5-bisphosphate D Kim, EJ Cavanaugh, D Simkin American Journal of Physiology-Cell Physiology 295 (1), C92-C99, 2008 | 109 | 2008 |
| Aging-related hyperexcitability in CA3 pyramidal neurons is mediated by enhanced A-type K+ channel function and expression D Simkin, S Hattori, N Ybarra, TF Musial, EW Buss, H Richter, MM Oh, ... Journal of Neuroscience 35 (38), 13206-13218, 2015 | 96 | 2015 |
| Supramolecular nanostructure activates TrkB receptor signaling of neuronal cells by mimicking brain-derived neurotrophic factor AN Edelbrock, Z Àlvarez, D Simkin, T Fyrner, SM Chin, K Sato, E Kiskinis, ... Nano letters 18 (10), 6237-6247, 2018 | 92 | 2018 |
| Activation of transient receptor potential A1 channels by mustard oil, tetrahydrocannabinol and Ca2+ reveals different functional channel states EJ Cavanaugh, D Simkin, D Kim Neuroscience 154 (4), 1467-1476, 2008 | 92 | 2008 |
| Control of the single channel conductance of K2P10. 1 (TREK‐2) by the amino‐terminus: role of alternative translation initiation D Simkin, EJ Cavanaugh, D Kim The Journal of physiology 586 (23), 5651-5663, 2008 | 84 | 2008 |
| Intrinsic hippocampal excitability changes of opposite signs and different origins in CA1 and CA3 pyramidal neurons underlie aging-related cognitive deficits MM Oh, D Simkin, JF Disterhoft Frontiers in systems neuroscience 10, 52, 2016 | 65 | 2016 |
| Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls D Simkin, V Papakis, BI Bustos, CM Ambrosi, SJ Ryan, V Baru, ... Stem Cell Reports 17 (4), 993-1008, 2022 | 43 | 2022 |
| Skeletal Muscle Na+ Channel Disorders D Simkin, S Bendahhou Frontiers in pharmacology 2, 63, 2011 | 35 | 2011 |
| Cognitive aging is associated with redistribution of synaptic weights in the hippocampus EW Buss, NJ Corbett, JG Roberts, N Ybarra, TF Musial, D Simkin, ... Proceedings of the National Academy of Sciences 118 (8), e1921481118, 2021 | 29 | 2021 |
| Dyshomeostatic modulation of Ca2+-activated K+ channels in a human neuronal model of KCNQ2 encephalopathy D Simkin, KA Marshall, CG Vanoye, RR Desai, BI Bustos, BN Piyevsky, ... Elife 10, e64434, 2021 | 29 | 2021 |
| Osteogenic and chondrogenic master genes expression is dependent on the Kir2. 1 potassium channel through the bone morphogenetic protein pathway J Pini, S Giuliano, J Matonti, L Gannoun, D Simkin, M Rouleau, ... Journal of Bone and Mineral Research 33 (10), 1826-1841, 2018 | 29 | 2018 |
| Modeling pediatric epilepsy through iPSC-based technologies D Simkin, E Kiskinis Epilepsy currents 18 (4), 240-245, 2018 | 26 | 2018 |
| Mechanisms underlying Andersen's syndrome pathology in skeletal muscle are revealed in human myotubes S Sacconi, D Simkin, N Arrighi, F Chapon, MM Larroque, S Vicart, ... American Journal of Physiology-Cell Physiology 297 (4), C876-C885, 2009 | 26 | 2009 |
| Mechanisms underlying a life‐threatening skeletal muscle Na+ channel disorder D Simkin, I Léna, P Landrieu, L Lion‐François, D Sternberg, B Fontaine, ... The Journal of physiology 589 (13), 3115-3124, 2011 | 19 | 2011 |
| Evaluation of HCN2 abnormalities as a cause of juvenile audiogenic seizures in Black Swiss mice M Shin, D Simkin, GM Suyeoka, DM Chetkovich Brain research 1083 (1), 14-20, 2006 | 19 | 2006 |
| Peptide–siRNA supramolecular particles for neural cell transfection A Hernandez‐Garcia, Z Álvarez, D Simkin, A Madhan, E Pariset, ... Advanced Science 6 (3), 1801458, 2019 | 16 | 2019 |
| ‘Channeling’therapeutic discovery for epileptic encephalopathy through iPSC technologies D Simkin, C Ambrosi, KA Marshall, LA Williams, J Eisenberg, M Gharib, ... Trends in Pharmacological Sciences 43 (5), 392-405, 2022 | 13 | 2022 |
| Excitatory dysfunction drives network and calcium handling deficits in 16p11. 2 duplication schizophrenia induced pluripotent stem cell–derived neurons E Parnell, L Culotta, MP Forrest, HA Jalloul, BL Eckman, DD Loizzo, ... Biological psychiatry 94 (2), 153-163, 2023 | 10 | 2023 |
| Rescue of neuropsychiatric phenotypes in a mouse model of 16p11. 2 duplication syndrome by genetic correction of an epilepsy network hub MP Forrest, M Dos Santos, NH Piguel, YZ Wang, NA Hawkins, VA Bagchi, ... Nature communications 14 (1), 825, 2023 | 7 | 2023 |
| Andersen’s syndrome mutants produce a knockdown of inwardly rectifying K+ channel in mouse skeletal muscle in vivo D Simkin, G Robin, S Giuliano, A Vukolic, P Moceri, N Guy, KD Wagner, ... Cell and tissue research 371, 309-323, 2018 | 5 | 2018 |
