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Heidi Högel
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Serum glial fibrillary acidic protein correlates with multiple sclerosis disease severity
H Högel, E Rissanen, C Barro, M Matilainen, M Nylund, J Kuhle, L Airas
Multiple Sclerosis Journal 26 (2), 210-219, 2020
1292020
Prolyl hydroxylase PHD3 activates oxygen-dependent protein aggregation
K Rantanen, J Pursiheimo, H Högel, V Himanen, E Metzen, PM Jaakkola
Molecular biology of the cell 19 (5), 2231-2240, 2008
852008
Prolyl hydroxylase PHD3 enhances the hypoxic survival and G1 to S transition of carcinoma cells
H Högel, K Rantanen, T Jokilehto, R Grenman, PM Jaakkola
PloS one 6 (11), e27112, 2011
582011
Hypoxia-inducible factor (HIF)-prolyl hydroxylase 3 (PHD3) maintains high HIF2A mRNA levels in clear cell renal cell carcinoma
P Miikkulainen, H Högel, F Seyednasrollah, K Rantanen, LL Elo, ...
Journal of Biological Chemistry 294 (10), 3760-3771, 2019
332019
p62/SQSTM1 regulates cellular oxygen sensing by attenuating PHD3 activity through aggregate sequestration and enhanced degradation
K Rantanen, JP Pursiheimo, H Högel, P Miikkulainen, J Sundström, ...
Journal of cell science 126 (5), 1144-1154, 2013
312013
Hypoxia inducible prolyl hydroxylase PHD3 maintains carcinoma cell growth by decreasing the stability of p27
H Högel, P Miikkulainen, L Bino, PM Jaakkola
Molecular cancer 14 (1), 1-14, 2015
282015
Positron emission tomography imaging in evaluation of MS pathology in vivo
H Högel, E Rissanen, A Vuorimaa, L Airas
Multiple Sclerosis, 2018
272018
HIF prolyl hydroxylase PHD3 regulates translational machinery and glucose metabolism in clear cell renal cell carcinoma
P Miikkulainen, H Högel, K Rantanen, T Suomi, P Kouvonen, LL Elo, ...
Cancer & metabolism 5 (1), 5, 2017
242017
Retention of prolyl hydroxylase PHD2 in the cytoplasm prevents PHD2-induced anchorage-independent carcinoma cell growth
T Jokilehto, H Högel, P Heikkinen, K Rantanen, K Elenius, J Sundström, ...
Experimental cell research 316 (7), 1169-1178, 2010
172010
Transportable system enabling multiple irradiation studies under simultaneous hypoxia in vitro
O Metsälä, J Kreutzer, H Högel, P Miikkulainen, P Kallio, PM Jaakkola
Radiation oncology 13 (1), 1-11, 2018
162018
Uptake of [18F] EF5 as a tracer for hypoxic and aggressive phenotype in experimental head and neck squamous cell carcinoma
J Silén, H Högel, K Kivinen, A Silvoniemi, S Forsback, E Löyttyniemi, ...
Translational oncology 7 (3), 323-330, 2014
112014
Serum GFAP Associates with Neurofilament Light and Disease Severity in Late Multiple Sclerosis (P5. 2-017)
L Airas, H Hoegel, E Rissanen, M Matilainen, M Nylund, J Kuhle
Neurology 92 (15 Supplement), P5. 2-017, 2019
2019
Life without Phd?–Phd Oxygen Sensor Proteins in Hypoxic Carcinoma Cell Survival
H Högel
2016
223: HIF prolyl hydroxylase PHD3 maintains hypoxic cell cycle through cyclin-dependent kinase inhibitor P27
H Högel, P Miikkulainen, L Bino, PM Jaakkola
European Journal of Cancer 50, S51, 2014
2014
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Articles 1–14