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Jane Endicott
Jane Endicott
Professor of Cancer Structural Biology, Newcastle University
Verified email at ncl.ac.uk - Homepage
Title
Cited by
Cited by
Year
The biochemistry of P-glycoprotein-mediated multidrug resistance
JA Endicott, V Ling
Annual review of biochemistry 58 (1), 137-171, 1989
27871989
Protein kinase inhibitors: insights into drug design from structure
MEM Noble, JA Endicott, LN Johnson
Science 303 (5665), 1800-1805, 2004
16732004
Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases
R Hoessel, S Leclerc, JA Endicott, MEM Nobel, A Lawrie, P Tunnah, ...
Nature cell biology 1 (1), 60-67, 1999
10331999
Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance
JH Gerlach, JA Endicott, PF Juranka, G Henderson, F Sarangi, ...
Nature 324 (6096), 485-489, 1986
8461986
The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases
NR Brown, MEM Noble, JA Endicott, LN Johnson
Nature cell biology 1 (7), 438-443, 1999
6931999
The structural basis for control of eukaryotic protein kinases
JA Endicott, MEM Noble, LN Johnson
Annual review of biochemistry 81, 587-613, 2012
4852012
Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2.
AM Lawrie, ME Noble, P Tunnah, NR Brown, LN Johnson, JA Endicott
Nature structural biology 4 (10), 796-801, 1997
3341997
Molecular basis for the recognition of phosphorylated and phosphoacetylated histone h3 by 14-3-3
N Macdonald, JPI Welburn, MEM Noble, A Nguyen, MB Yaffe, D Clynes, ...
Molecular cell 20 (2), 199-211, 2005
2902005
Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor
TG Davies, J Bentley, CE Arris, FT Boyle, NJ Curtin, JA Endicott, ...
Nature structural biology 9 (10), 745-749, 2002
2782002
Effects of phosphorylation of threonine 160 on cyclin-dependent kinase 2 structure and activity
NR Brown, MEM Noble, AM Lawrie, MC Morris, P Tunnah, G Divita, ...
Journal of Biological Chemistry 274 (13), 8746-8756, 1999
2741999
Identification of novel purine and pyrimidine cyclin-dependent kinase inhibitors with distinct molecular interactions and tumor cell growth inhibition profiles
CE Arris, FT Boyle, AH Calvert, NJ Curtin, JA Endicott, EF Garman, ...
Journal of medicinal chemistry 43 (15), 2797-2804, 2000
2682000
The crystal structure of cyclin A
NR Brown, MEM Noble, JA Endicott, EF Garman, S Wakatsuki, E Mitchell, ...
Structure 3 (11), 1235-1247, 1995
2561995
CR8, a potent and selective, roscovitine-derived inhibitor of cyclin-dependent kinases
K Bettayeb, N Oumata, A Echalier, Y Ferandin, JA Endicott, H Galons, ...
Oncogene 27 (44), 5797-5807, 2008
2102008
Structural insights into the functional diversity of the CDK–cyclin family
DJ Wood, JA Endicott
Open biology 8 (9), 180112, 2018
2042018
Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP
M Lu, H Breyssens, V Salter, S Zhong, Y Hu, C Baer, I Ratnayaka, ...
Cancer cell 23 (5), 618-633, 2013
1972013
Aloisines, a new family of CDK/GSK-3 inhibitors. SAR study, crystal structure in complex with CDK2, enzyme selectivity, and cellular effects
Y Mettey, M Gompel, V Thomas, M Garnier, M Leost, I Ceballos-Picot, ...
Journal of medicinal chemistry 46 (2), 222-236, 2003
1952003
Inhibitor binding to active and inactive CDK2: the crystal structure of CDK2-cyclin A/indirubin-5-sulphonate
TG Davies, P Tunnah, L Meijer, D Marko, G Eisenbrand, JA Endicott, ...
Structure 9 (5), 389-397, 2001
1872001
The cyclin box fold: protein recognition in cell-cycle and transcription control
MEM Noble, JA Endicott, NR Brown, LN Johnson
Trends in biochemical sciences 22 (12), 482-487, 1997
1851997
CDK1 structures reveal conserved and unique features of the essential cell cycle CDK
NR Brown, S Korolchuk, MP Martin, WA Stanley, R Moukhametzianov, ...
Nature communications 6 (1), 1-12, 2015
1822015
Meriolins (3-(pyrimidin-4-yl)-7-azaindoles): synthesis, kinase inhibitory activity, cellular effects, and structure of a CDK2/cyclin A/meriolin complex
A Echalier, K Bettayeb, Y Ferandin, O Lozach, M Clément, A Valette, ...
Journal of medicinal chemistry 51 (4), 737-751, 2008
1742008
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