| Antidepressant drugs act by directly binding to TRKB neurotrophin receptors PC Casarotto, M Girych, SM Fred, V Kovaleva, R Moliner, G Enkavi, ... Cell 184 (5), 1299-1313. e19, 2021 | 401 | 2021 |
| Pharmacologically diverse antidepressants rapidly activate brain-derived neurotrophic factor receptor TrkB and induce phospholipase-Cγ signaling pathways in mouse brain T Rantamäki, P Hendolin, A Kankaanpää, J Mijatovic, P Piepponen, ... Neuropsychopharmacology 32 (10), 2152-2162, 2007 | 357 | 2007 |
| Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson’s disease G Mudo, J Mäkelä, VD Liberto, TV Tselykh, M Olivieri, P Piepponen, ... Cellular and Molecular Life Sciences 69, 1153-1165, 2012 | 330 | 2012 |
| Mesolimbic dopamine release is linked to symptom severity in pathological gambling J Joutsa, J Johansson, S Niemelä, A Ollikainen, MM Hirvonen, ... Neuroimage 60 (4), 1992-1999, 2012 | 235 | 2012 |
| Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons M Palgi, R Lindström, J Peränen, TP Piepponen, M Saarma, TI Heino Proceedings of the National Academy of Sciences 106 (7), 2429-2434, 2009 | 181 | 2009 |
| Analysis of acetylcholine and choline in microdialysis samples by liquid chromatography/tandem mass spectrometry P Uutela, R Reinilä, P Piepponen, RA Ketola, R Kostiainen Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2005 | 126 | 2005 |
| GDNF overexpression from the native locus reveals its role in the nigrostriatal dopaminergic system function A Kumar, J Kopra, K Varendi, LL Porokuokka, A Panhelainen, S Kuure, ... PLoS genetics 11 (12), e1005710, 2015 | 122 | 2015 |
| Rapid and sensitive step gradient assays of glutamate, glycine, taurine and γ-aminobutyric acid by high-performance liquid chromatography–fluorescence detection with o … TP Piepponen, A Skujins Journal of Chromatography B: Biomedical Sciences and Applications 757 (2 …, 2001 | 115 | 2001 |
| Dicer and microRNAs protect adult dopamine neurons P Chmielarz, J Konovalova, SS Najam, H Alter, TP Piepponen, H Erfle, ... Cell death & disease 8 (5), e2813-e2813, 2017 | 99 | 2017 |
| Constitutive Ret activity in knock-in multiple endocrine neoplasia type B mice induces profound elevation of brain dopamine concentration via enhanced synthesis and increases … J Mijatovic, M Airavaara, A Planken, P Auvinen, A Raasmaja, ... Journal of Neuroscience 27 (18), 4799-4809, 2007 | 88 | 2007 |
| Discovery of dopamine glucuronide in rat and mouse brain microdialysis samples using liquid chromatography tandem mass spectrometry P Uutela, L Karhu, P Piepponen, M Kaenmaki, RA Ketola, R Kostiainen Analytical chemistry 81 (1), 427-434, 2009 | 83 | 2009 |
| Analysis of intact glucuronides and sulfates of serotonin, dopamine, and their phase I metabolites in rat brain microdialysates by liquid chromatography− tandem mass spectrometry P Uutela, R Reinila, K Harju, P Piepponen, RA Ketola, R Kostiainen Analytical chemistry 81 (20), 8417-8425, 2009 | 82 | 2009 |
| Comparison of different amino acid derivatives and analysis of rat brain microdialysates by liquid chromatography tandem mass spectrometry P Uutela, RA Ketola, P Piepponen, R Kostiainen Analytica chimica acta 633 (2), 223-231, 2009 | 79 | 2009 |
| The effect of lipopolysaccharide (LPS) on inflammatory markers in blood and brain and on behavior in individually-housed pigs J Nordgreen, C Munsterhjelm, F Aae, A Popova, P Boysen, B Ranheim, ... Physiology & behavior 195, 98-111, 2018 | 73 | 2018 |
| GDNF is not required for catecholaminergic neuron survival in vivo J Kopra, C Vilenius, S Grealish, MA Härma, K Varendi, J Lindholm, ... Nature neuroscience 18 (3), 319-322, 2015 | 72 | 2015 |
| Increased extracellular dopamine concentrations and FosB/ΔFosB expression in striatal brain areas of heterozygous GDNF knockout mice M Airavaara, A Planken, H Gäddnäs, TP Piepponen, M Saarma, L Ahtee European Journal of Neuroscience 20 (9), 2336-2344, 2004 | 70 | 2004 |
| In heterozygous GDNF knockout mice the response of striatal dopaminergic system to acute morphine is altered M Airavaara, J Mijatovic, T Vihavainen, TP Piepponen, M Saarma, ... Synapse 59 (6), 321-329, 2006 | 67 | 2006 |
| Effects of ethanol on the accumbal output of dopamine, GABA and glutamate in alcohol-tolerant and alcohol-nontolerant rats TP Piepponen, K Kiianmaa, L Ahtee Pharmacology Biochemistry and Behavior 74 (1), 21-30, 2002 | 63 | 2002 |
| Involvement of opioid μ1-receptors in opioid-induced acceleration of striatal and limbic dopaminergic transmission TP Piepponen, A Honkanen, T Kivastik, A Zharkovsky, A Turtia, ... Pharmacology Biochemistry and Behavior 63 (2), 245-252, 1999 | 61 | 1999 |
| Involvement of opioid μ1 receptors in morphine-induced conditioned place preference in rats TP Piepponen, T Kivastik, J Katajamäki, A Zharkovsky, L Ahtee Pharmacology Biochemistry and Behavior 58 (1), 275-279, 1997 | 61 | 1997 |
jaan-olle andressooDepartment of Pharmacology/Helsinki Institute of Life Science, University of Helsinki, FinlandVahvistettu sähköpostiosoite verkkotunnuksessa helsinki.fi
