Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1 M Tahiliani, KP Koh, Y Shen, WA Pastor, H Bandukwala, Y Brudno, ... Science 324 (5929), 930-935, 2009 | 6390 | 2009 |
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2 M Ko, Y Huang, AM Jankowska, UJ Pape, M Tahiliani, HS Bandukwala, ... Nature 468 (7325), 839-843, 2010 | 1494 | 2010 |
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells KP Koh, A Yabuuchi, S Rao, Y Huang, K Cunniff, J Nardone, A Laiho, ... Cell stem cell 8 (2), 200-213, 2011 | 862 | 2011 |
Tumour hypoxia causes DNA hypermethylation by reducing TET activity B Thienpont, J Steinbacher, H Zhao, F D’Anna, A Kuchnio, A Ploumakis, ... Nature 537 (7618), 63-68, 2016 | 581 | 2016 |
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX M Ko, J An, HS Bandukwala, L Chavez, T Äijö, WA Pastor, MF Segal, H Li, ... Nature 497 (7447), 122-126, 2013 | 441 | 2013 |
Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening M Boretto, N Maenhoudt, X Luo, A Hennes, B Boeckx, B Bui, R Heremans, ... Nature cell biology 21 (8), 1041-1051, 2019 | 329 | 2019 |
Lineage-specific functions of TET1 in the postimplantation mouse embryo R Khoueiry, A Sohni, B Thienpont, X Luo, JV Velde, M Bartoccetti, ... Nature genetics 49 (7), 1061-1072, 2017 | 113 | 2017 |
DNA methylation and methylcytosine oxidation in cell fate decisions KP Koh, A Rao Current opinion in cell biology 25 (2), 152-161, 2013 | 104 | 2013 |
Selective oxidation of 5-methylcytosine by tet-family proteins A Rao, M Tahiliani, KP Koh, S Agarwal, A Iyer | 88 | 2010 |
Domain requirements and sequence specificity of DNA binding for the forkhead transcription factor FOXP3 KP Koh, MS Sundrud, A Rao PloS one 4 (12), e8109, 2009 | 69 | 2009 |
Dynamic Switching of Active Promoter and Enhancer Domains Regulates Tet1 and Tet2 Expression during Cell State Transitions between Pluripotency and … A Sohni, M Bartoccetti, R Khoueiry, L Spans, J Vande Velde, L De Troyer, ... Molecular and cellular biology 35 (6), 1026-1042, 2015 | 54 | 2015 |
PDGFRα+ cells in embryonic stem cell cultures represent the in vitro equivalent of the pre-implantation primitive endoderm precursors AL Nigro, A de Jaime-Soguero, R Khoueiry, DS Cho, GM Ferlazzo, ... Stem Cell Reports 8 (2), 318-333, 2017 | 30 | 2017 |
Selective oxidation of 5-methylcytosine by TET-family proteins A Rao, M Tahiliani, KP Koh, S Agarwal, A Iyer US Patent 9,447,452, 2016 | 27 | 2016 |
Selective oxidation of 5-methylcytosine by TET-family proteins A Rao, M Tahiliani, KP Koh, S Agarwal, A Iyer US Patent 10,031,131, 2018 | 23 | 2018 |
Wnt/β-catenin inhibition disrupts carboplatin resistance in isogenic models of triple-negative breast cancer WA Abreu de Oliveira, S Moens, Y El Laithy, BK van Der Veer, ... Frontiers in Oncology 11, 705384, 2021 | 22 | 2021 |
Detection of 5-hydroxymethylcytosine by glycosylation A Rao, M Tahiliani, KP Koh, S Agarwal, A Iyer US Patent 9,816,986, 2017 | 22 | 2017 |
Selective oxidation of 5-methylcytosine by tet-family proteins A Rao, M Tahiliani, KP Koh, S Agarwal, A Iyer US Patent App. 15/440,319, 2017 | 22 | 2017 |
Selective oxidation of 5-methylcytosine by TET-family proteins A Rao, M Tahiliani, KP Koh, S Agarwal, A Iyer US Patent 10,533,213, 2020 | 21 | 2020 |
Selective oxidation of 5-methylcytosine by tet-family proteins A Rao, M Tahiliani, KP Koh, S Agarwal, A Iyer US Patent App. 15/483,297, 2017 | 21 | 2017 |
Measuring a level of a 5-hydroxymethylcytosine in a sample from a subject having a cancer or suspected of having cancer A Rao, M Tahiliani, KP Koh, S Agarwal, A Iyer US Patent 10,041,938, 2018 | 20 | 2018 |