T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus M Shuda, H Feng, HJ Kwun, ST Rosen, O Gjoerup, PS Moore, Y Chang Proceedings of the National Academy of Sciences 105 (42), 16272-16277, 2008 | 766 | 2008 |
Human Merkel cell polyomavirus infection I. MCV T antigen expression in Merkel cell carcinoma, lymphoid tissues and lymphoid tumors M Shuda, R Arora, HJ Kwun, H Feng, R Sarid, MT Fernández‐Figueras, ... International journal of cancer 125 (6), 1243-1249, 2009 | 407 | 2009 |
Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase JJ Zhao, OV Gjoerup, RR Subramanian, Y Cheng, W Chen, TM Roberts, ... Cancer cell 3 (5), 483-495, 2003 | 350 | 2003 |
The p110α isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation JJ Zhao, H Cheng, S Jia, L Wang, OV Gjoerup, A Mikami, TM Roberts Proceedings of the National Academy of Sciences 103 (44), 16296-16300, 2006 | 271 | 2006 |
SIK1 couples LKB1 to p53-dependent anoikis and suppresses metastasis H Cheng, P Liu, ZC Wang, L Zou, S Santiago, V Garbitt, OV Gjoerup, ... Science signaling 2 (80), ra35-ra35, 2009 | 185 | 2009 |
Update on human polyomaviruses and cancer O Gjoerup, Y Chang Advances in cancer research 106, 1-51, 2010 | 155 | 2010 |
Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding J Hein, S Boichuk, J Wu, Y Cheng, R Freire, PS Jat, TM Roberts, ... Journal of virology 83 (1), 117-127, 2009 | 147 | 2009 |
Cellular and viral factors regulating Merkel cell polyomavirus replication H Feng, HJ Kwun, X Liu, O Gjoerup, DB Stolz, Y Chang, PS Moore PloS one 6 (7), e22468, 2011 | 146 | 2011 |
Protein phosphatase 2A regulates life and death decisions via Akt in a context-dependent manner S Andrabi, OV Gjoerup, JA Kean, TM Roberts, B Schaffhausen Proceedings of the National Academy of Sciences 104 (48), 19011-19016, 2007 | 145 | 2007 |
Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1 M Cotsiki, RL Lock, Y Cheng, GL Williams, J Zhao, D Perera, R Freire, ... Proceedings of the National Academy of Sciences 101 (4), 947-952, 2004 | 141 | 2004 |
Clinical and analytical validation of FoundationOne®CDx, a comprehensive genomic profiling assay for solid tumors CA Milbury, J Creeden, WK Yip, DL Smith, V Pattani, K Maxwell, ... PLoS One 17 (3), e0264138, 2022 | 132 | 2022 |
Genomic analysis of circulating tumor DNA in 3,334 patients with advanced prostate cancer identifies targetable BRCA alterations and AR resistance mechanisms H Tukachinsky, RW Madison, JH Chung, OV Gjoerup, EA Severson, ... Clinical Cancer Research 27 (11), 3094-3105, 2021 | 129 | 2021 |
Rac and Cdc42 are potent stimulators of E2F-dependent transcription capable of promoting retinoblastoma susceptibility gene product hyperphosphorylation O Gjoerup, J Lukas, J Bartek, BM Willumsen Journal of Biological Chemistry 273 (30), 18812-18818, 1998 | 105 | 1998 |
Multiple DNA damage signaling and repair pathways deregulated by simian virus 40 large T antigen S Boichuk, L Hu, J Hein, OV Gjoerup Journal of virology 84 (16), 8007-8020, 2010 | 103 | 2010 |
An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer J Li, PS Choi, CL Chaffer, K Labella, JH Hwang, AO Giacomelli, JW Kim, ... Elife 7, e37184, 2018 | 102 | 2018 |
Merkel cell polyomavirus large T antigen disrupts lysosome clustering by translocating human Vam6p from the cytoplasm to the nucleus X Liu, J Hein, SCW Richardson, PH Basse, T Toptan, PS Moore, ... Journal of Biological Chemistry 286 (19), 17079-17090, 2011 | 94 | 2011 |
Activation of p21-activated kinase 6 by MAP kinase kinase 6 and p38 MAP kinase R Kaur, X Liu, O Gjoerup, A Zhang, X Yuan, SP Balk, MC Schneider, ... Journal of Biological Chemistry 280 (5), 3323-3330, 2005 | 80 | 2005 |
Tangled webs: evidence of cross-talk between c-Raf-1 and Akt T Jun, O Gjoerup, TM Roberts Science's STKE 1999 (13), pe1-pe1, 1999 | 77 | 1999 |
Bub1: escapades in a cellular world GL Williams, TM Roberts, OV Gjoerup Cell cycle 6 (14), 1699-1704, 2007 | 76 | 2007 |
Functional connection between Rad51 and PML in homology-directed repair S Boichuk, L Hu, K Makielski, PP Pandolfi, OV Gjoerup PloS one 6 (10), e25814, 2011 | 75 | 2011 |