Philippe Froguel
Philippe Froguel
Imperial College London and CNRS-Lille univ
Vahvistettu sähköpostiosoite verkkotunnuksessa
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
T Yamauchi, J Kamon, H Waki, Y Terauchi, N Kubota, K Hara, Y Mori, ...
Nature medicine 7 (8), 941, 2001
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase
T Yamauchi, J Kamon, Y Minokoshi, Y Ito, H Waki, S Uchida, S Yamashita, ...
Nature medicine 8 (11), 1288, 2002
Cloning of adiponectin receptors that mediate antidiabetic metabolic effects
T Yamauchi, J Kamon, Y Ito, A Tsuchida, T Yokomizo, S Kita, T Sugiyama, ...
Nature 423 (6941), 762, 2003
A genome-wide association study identifies novel risk loci for type 2 diabetes
R Sladek, G Rocheleau, J Rung, C Dina, L Shen, D Serre, P Boutin, ...
Nature 445 (7130), 881, 2007
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
K Clement, C Vaisse, N Lahlou, S Cabrol, V Pelloux, D Cassuto, ...
Nature 392 (6674), 398, 1998
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, ...
Nature genetics 42 (11), 937, 2010
Genetic studies of body mass index yield new insights for obesity biology
AE Locke, B Kahali, SI Berndt, AE Justice, TH Pers, FR Day, C Powell, ...
Nature 518 (7538), 197, 2015
Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3)
K Yamagata, N Oda, PJ Kaisaki, S Menzel, H Furuta, M Vaxillaire, ...
Nature 384 (6608), 455, 1996
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
J Dupuis, C Langenberg, I Prokopenko, R Saxena, N Soranzo, ...
Nature genetics 42 (2), 105, 2010
Disruption of adiponectin causes insulin resistance and neointimal formation
N Kubota, Y Terauchi, T Yamauchi, T Kubota, M Moroi, J Matsui, K Eto, ...
Journal of Biological Chemistry 277 (29), 25863-25866, 2002
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
BF Voight, LJ Scott, V Steinthorsdottir, AP Morris, C Dina, RP Welch, ...
Nature genetics 42 (7), 579, 2010
Translating the A1C assay into estimated average glucose values
DM Nathan, J Kuenen, R Borg, H Zheng, D Schoenfeld, RJ Heine
Diabetes care 31 (8), 1473-1478, 2008
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
AP Morris, BF Voight, TM Teslovich, T Ferreira, AV Segre, ...
Nature genetics 44 (9), 981, 2012
Variation in FTO contributes to childhood obesity and severe adult obesity
C Dina, D Meyre, S Gallina, E Durand, A Körner, P Jacobson, ...
Nature genetics 39 (6), 724, 2007
Common variants near MC4R are associated with fat mass, weight and risk of obesity
RJF Loos, CM Lindgren, S Li, E Wheeler, JH Zhao, I Prokopenko, ...
Nature genetics 40 (6), 768, 2008
Defining the role of common variation in the genomic and biological architecture of adult human height
AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ...
Nature genetics 46 (11), 1173, 2014
Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions
T Yamauchi, Y Nio, T Maki, M Kobayashi, T Takazawa, M Iwabu, ...
Nature medicine 13 (3), 332, 2007
Globular adiponectin protected ob/ob mice from diabetes and ApoE-deficient mice from atherosclerosis
T Yamauchi, J Kamon, H Waki, Y Imai, N Shimozawa, K Hioki, S Uchida, ...
Journal of Biological Chemistry 278 (4), 2461-2468, 2003
Genetic associations with human longevity at the APOE and ACE loci
F Schächter, L Faure-Delanef, F Guénot, H Rouger, P Froguel, ...
Nature genetics 6 (1), 29, 1994
Impaired multimerization of human adiponectin mutants associated with diabetes molecular structure and multimer formation of adiponectin
H Waki, T Yamauchi, J Kamon, Y Ito, S Uchida, S Kita, K Hara, Y Hada, ...
Journal of Biological Chemistry 278 (41), 40352-40363, 2003
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Artikkelit 1–20