| Single-cell fluorescence resonance energy transfer analysis demonstrates that caspase activation during apoptosis is a rapid process: role of caspase-3 M Rehm, H Dussmann, RU Janicke, JM Tavare, D Kogel, JHM Prehn Journal of Biological Chemistry 277 (27), 24506-24514, 2002 | 361 | 2002 |
| Systems analysis of effector caspase activation and its control by X‐linked inhibitor of apoptosis protein M Rehm, HJ Huber, H Dussmann, JHM Prehn The EMBO journal 25 (18), 4338-4349, 2006 | 250 | 2006 |
| Real-time single cell analysis of Smac/DIABLO release during apoptosis M Rehm, H Düßmann, JHM Prehn The Journal of cell biology 162 (6), 1031-1043, 2003 | 176 | 2003 |
| Versatile Conjugated Polymer Nanoparticles for High-Resolution O2 Imaging in Cells and 3D Tissue Models RI Dmitriev, SM Borisov, H Düssmann, S Sun, BJ Müller, J Prehn, ... ACS nano 9 (5), 5275-5288, 2015 | 163 | 2015 |
| Proteasome inhibition can induce an autophagy-dependent apical activation of caspase-8 MA Laussmann, E Passante, H Düssmann, JA Rauen, ML Würstle, ... Cell Death & Differentiation 18 (10), 1584-1597, 2011 | 153 | 2011 |
| Dynamics of outer mitochondrial membrane permeabilization during apoptosis M Rehm, HJ Huber, CT Hellwig, S Anguissola, H Dussmann, JHM Prehn Cell Death & Differentiation 16 (4), 613-623, 2009 | 152 | 2009 |
| Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases N Connolly, P Theurey, V Adam-Vizi, NG Bazan, P Bernardi, JP Bolaños, ... Cell Death & Differentiation 25 (3), 542-572, 2018 | 148 | 2018 |
| Outer mitochondrial membrane permeabilization during apoptosis triggers caspase-independent mitochondrial and caspase-dependent plasma membrane potential depolarization: a … H Düßmann, M Rehm, D Kögel, JHM Prehn Journal of cell science 116 (3), 525-536, 2003 | 141 | 2003 |
| Mitochondrial and plasma membrane potential of cultured cerebellar neurons during glutamate-induced necrosis, apoptosis, and tolerance MW Ward, HJ Huber, P Weisová, H Düssmann, DG Nicholls, JHM Prehn Journal of Neuroscience 27 (31), 8238-8249, 2007 | 135 | 2007 |
| Imaging of single cell responses to ER stress indicates that the relative dynamics of IRE1/XBP1 and PERK/ATF4 signalling rather than a switch between signalling branches … F Walter, J Schmid, H Düssmann, CG Concannon, JHM Prehn Cell Death & Differentiation 22 (9), 1502-1516, 2015 | 126 | 2015 |
| Dissipation of potassium and proton gradients inhibits mitochondrial hyperpolarization and cytochrome c release during neural apoptosis M Poppe, C Reimertz, H Düßmann, AJ Krohn, CM Luetjens, ... Journal of Neuroscience 21 (13), 4551-4563, 2001 | 120 | 2001 |
| Single-cell quantification of Bax activation and mathematical modelling suggest pore formation on minimal mitochondrial Bax accumulation H Düssmann, M Rehm, CG Concannon, S Anguissola, M Würstle, ... Cell Death & Differentiation 17 (2), 278-290, 2010 | 113 | 2010 |
| Apoptosis induced by disruption of the actin cytoskeleton is mediated via activation of CD95 (Fas/APO-1) D Kulms, H Düssmann, B Pöppelmann, S Ständer, A Schwarz, T Schwarz Cell Death & Differentiation 9 (6), 598-608, 2002 | 113 | 2002 |
| Low levels of Caspase-3 predict favourable response to 5FU-based chemotherapy in advanced colorectal cancer: Caspase-3 inhibition as a therapeutic approach L Flanagan, M Meyer, J Fay, S Curry, O Bacon, H Duessmann, K John, ... Cell death & disease 7 (2), e2087-e2087, 2016 | 108 | 2016 |
| Real time single cell analysis of Bid cleavage and Bid translocation during caspase-dependent and neuronal caspase-independent apoptosis MW Ward, M Rehm, H Duessmann, S Kacmar, CG Concannon, ... Journal of Biological chemistry 281 (9), 5837-5844, 2006 | 104 | 2006 |
| ER stress signaling has an activating transcription factor 6α (ATF6)-dependent “off-switch” F Walter, A O'Brien, CG Concannon, H Düssmann, JHM Prehn Journal of Biological Chemistry 293 (47), 18270-18284, 2018 | 99 | 2018 |
| Motoneurons secrete angiogenin to induce RNA cleavage in astroglia A Skorupa, MA King, IM Aparicio, H Dussmann, K Coughlan, B Breen, ... Journal of Neuroscience 32 (15), 5024-5038, 2012 | 93 | 2012 |
| Calpains are downstream effectors of bax-dependent excitotoxic apoptosis B D'Orsi, H Bonner, LP Tuffy, H Düssmann, I Woods, MJ Courtney, ... Journal of Neuroscience 32 (5), 1847-1858, 2012 | 93 | 2012 |
| Two-step activation of FOXO3 by AMPK generates a coherent feed-forward loop determining excitotoxic cell fate D Davila, NMC Connolly, H Bonner, P Weisova, H Dussmann, ... Cell Death & Differentiation 19 (10), 1677-1688, 2012 | 81 | 2012 |
| Novel Benzylidene-9(10H)-anthracenones as Highly Active Antimicrotubule Agents. Synthesis, Antiproliferative Activity, and Inhibition of Tubulin Polymerization H Prinz, Y Ishii, T Hirano, T Stoiber, JA Camacho Gomez, P Schmidt, ... Journal of medicinal chemistry 46 (15), 3382-3394, 2003 | 81 | 2003 |
Jochen H M PrehnRoyal College of Surgeons in Ireland University of Medicine and Health SciencesVerified email at rcsi.ie
