Quinol-based cyclic antioxidant mechanism in estrogen neuroprotection L Prokai, K Prokai-Tatrai, P Perjesi, AD Zharikova, EJ Perez, R Liu, ... Proceedings of the National Academy of Sciences 100 (20), 11741-11746, 2003 | 222 | 2003 |
Targeting drugs to the brain by redox chemical delivery systems L Prokai, K Prokai‐Tatrai, N Bodor Medicinal research reviews 20 (5), 367-416, 2000 | 175 | 2000 |
Hydroxy metabolites of the Alzheimer's drug candidate 3-[(2, 4-dimethoxy) benzylidene]-anabaseine dihydrochloride (GTS-21): their molecular properties, interactions with brain … WR Kem, VM Mahnir, L Prokai, RL Papke, X Cao, S LeFrancois, ... Molecular pharmacology 65 (1), 56-67, 2004 | 117 | 2004 |
Brain-targeted delivery of a leucine-enkephalin analogue by retrometabolic design K Prokai-Tatrai, L Prokai, N Bodor Journal of medicinal chemistry 39 (24), 4775-4782, 1996 | 99 | 1996 |
Mechanistic investigations on the antioxidant action of a neuroprotective estrogen derivative K Prokai-Tatrai, P Perjesi, NM Rivera-Portalatin, JW Simpkins, L Prokai Steroids 73 (3), 280-288, 2008 | 94 | 2008 |
17β-Estradiol Eye Drops Protect the Retinal Ganglion Cell Layer and Preserve Visual Function in an in Vivo Model of Glaucoma K Prokai-Tatrai, H Xin, V Nguyen, S Szarka, B Blazics, L Prokai, P Koulen Molecular pharmaceutics 10 (8), 3253-3261, 2013 | 88 | 2013 |
Neuroprotective Effects of a Novel Non–Receptor-Binding Estrogen Analogue: In Vitro and In Vivo Analysis R Liu, SH Yang, E Perez, KD Yi, SS Wu, K Eberst, L Prokai, ... Stroke 33 (10), 2485-2491, 2002 | 87 | 2002 |
Anabaseine derivatives useful in the treatment of degenerative diseases of the nervous system WR Kem, JA Zoltewicz, EM Meyer, K Prokai-Tatrai US Patent 5,741,802, 1998 | 82 | 1998 |
Mechanistic insights into the direct antioxidant effects of estrogens L Prokai, K Prokai‐Tatrai, P Perjési, JW Simpkins Drug development research 66 (2), 118-125, 2005 | 79 | 2005 |
Factors that contribute to the misidentification of tyrosine nitration by shotgun proteomics SM Stevens, K Prokai-Tatrai, L Prokai Molecular & Cellular Proteomics 7 (12), 2442-2451, 2008 | 72 | 2008 |
Characterization of 4-hydroxy-2-nonenal-modified peptides by liquid chromatography− tandem mass spectrometry using data-dependent acquisition: Neutral loss-driven MS3 versus … N Rauniyar, SM Stevens Jr, K Prokai-Tatrai, L Prokai Analytical Chemistry 81 (2), 782-789, 2009 | 61 | 2009 |
The prodrug DHED selectively delivers 17β-estradiol to the brain for treating estrogen-responsive disorders L Prokai, V Nguyen, S Szarka, P Garg, G Sabnis, HA Bimonte-Nelson, ... Science Translational Medicine 7 (297), 297ra113-297ra113, 2015 | 58 | 2015 |
Synthesis and biological evaluation of 17β-alkoxyestra-1, 3, 5 (10)-trienes as potential neuroprotectants against oxidative stress L Prokai, SM Oon, K Prokai-Tatrai, KA Abboud, JW Simpkins Journal of medicinal chemistry 44 (1), 110-114, 2001 | 58 | 2001 |
Long range transmission of polar effects in cholinergic 3-arylidene anabaseines. Conformations calculated by molecular modelling JA Zoltewicz, K Prokai-Tatrai, LB Bloom, WR Kem Heterocycles 35, 171-179, 1993 | 58 | 1993 |
Metabolism-based brain-targeting system for a thyrotropin-releasing hormone analogue L Prokai, K Prokai-Tatrai, X Ouyang, HS Kim, WM Wu, A Zharikova, ... Journal of medicinal chemistry 42 (22), 4563-4571, 1999 | 52 | 1999 |
Pharmacokinetics and urinary excretion of DMXBA (GTS‐21), a compound enhancing cognition V Mahnir, B Lin, K Prokai‐Tatrai, WR Kem Biopharmaceutics & drug disposition 19 (3), 147-151, 1998 | 46 | 1998 |
Protein targets for carbonylation by 4-hydroxy-2-nonenal in rat liver mitochondria J Guo, K Prokai-Tatrai, V Nguyen, N Rauniyar, B Ughy, L Prokai Journal of proteomics 74 (11), 2370-2379, 2011 | 43 | 2011 |
Separation of dansylated 17β-estradiol, 17α-estradiol, and estrone on a single HPLC column for simultaneous quantitation by LC–MS/MS S Szarka, V Nguyen, L Prokai, K Prokai-Tatrai Analytical and bioanalytical chemistry 405, 3399-3406, 2013 | 42 | 2013 |
Application of screening experimental designs to assess chromatographic isotope effect upon isotope-coded derivatization for quantitative liquid chromatography–mass spectrometry S Szarka, K Prokai-Tatrai, L Prokai Analytical chemistry 86 (14), 7033-7040, 2014 | 41 | 2014 |
Centrally acting and metabolically stable thyrotropin-releasing hormone analogues by replacement of histidine with substituted pyridinium L Prokai, K Prokai-Tatrai, AD Zharikova, V Nguyen, P Perjesi, SM Stevens Journal of medicinal chemistry 47 (24), 6025-6033, 2004 | 38 | 2004 |