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Heikki Kuusanmäki
Heikki Kuusanmäki
Institute for Molecular Medicine Finland (FIMM), University of Helsinki
Verified email at helsinki.fi
Title
Cited by
Cited by
Year
Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia
HLM Koskela, S Eldfors, P Ellonen, AJ van Adrichem, H Kuusanmäki, ...
New England Journal of Medicine 366 (20), 1905-1913, 2012
8492012
Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia
HLM Rajala, S Eldfors, H Kuusanmäki, AJ Van Adrichem, T Olson, ...
Blood, The Journal of the American Society of Hematology 121 (22), 4541-4550, 2013
3212013
Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3
EM Haapaniemi, M Kaustio, HLM Rajala, AJ van Adrichem, L Kainulainen, ...
Blood, The Journal of the American Society of Hematology 125 (4), 639-648, 2015
2912015
Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia
H Kuusanmäki, AM Leppä, P Pölönen, M Kontro, O Dufva, D Deb, ...
Haematologica 105 (3), 708, 2020
1262020
Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target
O Dufva, M Kankainen, T Kelkka, N Sekiguchi, SA Awad, S Eldfors, ...
Nature communications 9 (1), 1567, 2018
1262018
Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia
M Kontro, H Kuusanmäki, S Eldfors, T Burmeister, EI Andersson, ...
Leukemia 28 (8), 1738-1742, 2014
1262014
Activating somatic mutations outside the SH2-domain of STAT3 in LGL leukemia
E Andersson, H Kuusanmäki, S Bortoluzzi, S Lagström, A Parsons, ...
Leukemia 30 (5), 1204-1208, 2016
902016
Implementing a functional precision medicine tumor board for acute myeloid leukemia
D Malani, A Kumar, O Brück, M Kontro, B Yadav, M Hellesøy, ...
Cancer discovery 12 (2), 388-401, 2022
852022
Idelalisib sensitivity and mechanisms of disease progression in relapsed TCF3-PBX1 acute lymphoblastic leukemia
S Eldfors, H Kuusanmäki, M Kontro, MM Majumder, A Parsons, H Edgren, ...
Leukemia 31 (1), 51-57, 2017
532017
Identification of precision treatment strategies for relapsed/refractory multiple myeloma by functional drug sensitivity testing
MM Majumder, R Silvennoinen, P Anttila, D Tamborero, S Eldfors, ...
Oncotarget 8 (34), 56338, 2017
442017
Novel drug candidates for blast phase chronic myeloid leukemia from high-throughput drug sensitivity and resistance testing
PO Pietarinen, T Pemovska, M Kontro, B Yadav, JP Mpindi, EI Andersson, ...
Blood cancer journal 5 (5), e309-e309, 2015
352015
Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia
H Kuusanmäki, O Dufva, M Vähä-Koskela, AM Leppä, J Huuhtanen, ...
Blood 141 (13), 1610-1625, 2023
322023
In silico and preclinical drug screening identifies dasatinib as a targeted therapy for T-ALL
S Laukkanen, T Grönroos, P Pölönen, H Kuusanmäki, J Mehtonen, ...
Blood cancer journal 7 (9), e604-e604, 2017
322017
Drug sensitivity profiling identifies potential therapies for lymphoproliferative disorders with overactive JAK/STAT3 signaling
H Kuusanmäki, O Dufva, E Parri, AJ van Adrichem, H Rajala, ...
Oncotarget 8 (57), 97516, 2017
302017
Patient-tailored design for selective co-inhibition of leukemic cell subpopulations
A Ianevski, J Lahtela, KK Javarappa, P Sergeev, BR Ghimire, P Gautam, ...
Science advances 7 (8), eabe4038, 2021
292021
Bayesian multi-source regression and monocyte-associated gene expression predict BCL-2 inhibitor resistance in acute myeloid leukemia
BS White, SA Khan, MJ Mason, M Ammad-Ud-Din, S Potdar, D Malani, ...
NPJ precision oncology 5 (1), 71, 2021
212021
Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors
PO Pietarinen, CA Eide, P Ayuda-Durán, S Potdar, H Kuusanmäki, ...
Oncotarget 8 (14), 22606, 2017
192017
Ex vivo venetoclax sensitivity testing predicts treatment response in acute myeloid leukemia
H Kuusanmäki, S Kytölä, I Vänttinen, T Ruokoranta, A Ranta, ...
Haematologica 108 (7), 1768, 2023
182023
Endogenous and combination retinoids are active in myelomonocytic leukemias
O Di Martino, H Niu, G Hadwiger, H Kuusanmaki, MA Ferris, A Vu, ...
haematologica 106 (4), 1008, 2021
182021
Identification of novel regulators of STAT3 activity
E Parri, H Kuusanmäki, AJ van Adrichem, M Kaustio, K Wennerberg
PloS one 15 (3), e0230819, 2020
172020
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Articles 1–20