Genes involved in the osteoarthritis process identified through genome wide expression analysis in articular cartilage; the RAAK study YFM Ramos, W den Hollander, JVMG Bovée, N Bomer, ... PloS one 9 (7), e103056, 2014 | 185 | 2014 |
Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31 U Styrkarsdottir, G Thorleifsson, HT Helgadottir, N Bomer, S Metrustry, ... Nature genetics 46 (5), 498-502, 2014 | 169 | 2014 |
Metabolomics profile in depression: a pooled analysis of 230 metabolic markers in 5283 cases with depression and 10,145 controls M Bot, Y Milaneschi, T Al-Shehri, N Amin, S Garmaeva, GLJ Onderwater, ... Biological psychiatry 87 (5), 409-418, 2020 | 158 | 2020 |
Knee and hip articular cartilage have distinct epigenomic landscapes: implications for future cartilage regeneration approaches W Den Hollander, YFM Ramos, SD Bos, N Bomer, R van Der Breggen, ... Annals of the Rheumatic Diseases 73 (12), 2208-2212, 2014 | 119 | 2014 |
Selenium and outcome in heart failure N Bomer, N Grote Beverborg, MF Hoes, KW Streng, M Vermeer, ... European journal of heart failure 22 (8), 1415-1423, 2020 | 112 | 2020 |
Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis N Bomer, W den Hollander, YFM Ramos, SD Bos, R van der Breggen, ... Annals of the rheumatic diseases 74 (8), 1571-1579, 2015 | 98 | 2015 |
Heritability estimates for 361 blood metabolites across 40 genome-wide association studies FA Hagenbeek, R Pool, J van Dongen, HHM Draisma, J Jan Hottenga, ... Nature communications 11 (1), 39, 2020 | 75 | 2020 |
Modeling human cardiac hypertrophy in stem cell-derived cardiomyocytes E Ovchinnikova, M Hoes, K Ustyantsev, N Bomer, TV de Jong, ... Stem cell reports 10 (3), 794-807, 2018 | 65 | 2018 |
Dynamic loading of human engineered heart tissue enhances contractile function and drives a desmosome-linked disease phenotype JM Bliley, MCSC Vermeer, RM Duffy, I Batalov, D Kramer, JW Tashman, ... Science translational medicine 13 (603), eabd1817, 2021 | 62 | 2021 |
Transcriptional associations of osteoarthritis‐mediated loss of epigenetic control in articular cartilage W den Hollander, YFM Ramos, N Bomer, S Elzinga, R van der Breggen, ... Arthritis & rheumatology 67 (8), 2108-2116, 2015 | 62 | 2015 |
Selenium, selenoproteins, and heart failure: current knowledge and future perspective AA Al-Mubarak, P van der Meer, N Bomer Current heart failure reports 18, 122-131, 2021 | 59 | 2021 |
Metabolic Age Based on the BBMRI-NL 1H-NMR Metabolomics Repository as Biomarker of Age-related Disease EB Van Den Akker, S Trompet, JJH Barkey Wolf, M Beekman, ... Circulation: Genomic and Precision Medicine 13 (5), 541-547, 2020 | 52 | 2020 |
Concise review: the current state of human in vitro cardiac disease modeling: a focus on gene editing and tissue engineering MF Hoes, N Bomer, P Meer Stem cells translational medicine 8 (1), 66-74, 2019 | 45 | 2019 |
The effect of forced exercise on knee joints in Dio2−/− mice: type II iodothyronine deiodinase-deficient mice are less prone to develop OA-like cartilage damage upon excessive … N Bomer, FMF Cornelis, YFM Ramos, W den Hollander, L Storms, ... Annals of the rheumatic diseases 75 (3), 571-577, 2016 | 38 | 2016 |
Annotating transcriptional effects of genetic variants in disease‐relevant tissue: transcriptome‐wide allelic imbalance in osteoarthritic cartilage W den Hollander, I Pulyakhina, C Boer, N Bomer, R van der Breggen, ... Arthritis & Rheumatology 71 (4), 561-570, 2019 | 37 | 2019 |
Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy N Grote Beverborg, D Später, R Knöll, A Hidalgo, ST Yeh, Z Elbeck, ... Nature communications 12 (1), 5180, 2021 | 36 | 2021 |
Neo-cartilage engineered from primary chondrocytes is epigenetically similar to autologous cartilage, in contrast to using mesenchymal stem cells N Bomer, W den Hollander, H Suchiman, E Houtman, RC Slieker, ... Osteoarthritis and cartilage 24 (8), 1423-1430, 2016 | 36 | 2016 |
Micronutrient deficiencies in heart failure: Mitochondrial dysfunction as a common pathophysiological mechanism? N Bomer, MG Pavez‐Giani, N Grote Beverborg, JGF Cleland, ... Journal of Internal Medicine 291 (6), 713-731, 2022 | 30 | 2022 |
In peripartum cardiomyopathy plasminogen activator inhibitor-1 is a potential new biomarker with controversial roles M Ricke-Hoch, MF Hoes, TJ Pfeffer, S Schlothauer, J Nonhoff, S Haidari, ... Cardiovascular Research 116 (11), 1875-1886, 2020 | 28 | 2020 |
The role of cathepsin D in the pathophysiology of heart failure and its potentially beneficial properties: a translational approach MF Hoes, J Tromp, W Ouwerkerk, N Bomer, SU Oberdorf‐Maass, ... European journal of heart failure 22 (11), 2102-2111, 2020 | 27 | 2020 |